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gamma-Mangostin alleviates liver fibrosis through Sirtuin 3-superoxide-high mobility group box 1 signaling axis Journal article
TOXICOLOGY AND APPLIED PHARMACOLOGY, 2019,Volume: 363,Page: 142-153
Authors:  Wang A;  Zhou F;  Li D;  Lu JJ;  Wang Y;  Lin L
Favorite | View/Download:12/0 | TC[WOS]:3 TC[Scopus]:0 | Submit date:2020/03/20
Superoxide  Gamma-mangostin  Fibrogenesis  Sirtuin 3  Liver Fibrosis  Hmgb1  
Pinocembrin from Penthorum chinense Pursh suppresses hepatic stellate cells activation through a unified SIRT3-TGF-β-Smad signaling pathway Journal article
Toxicology and Applied Pharmacology, 2018,Volume: 341,Page: 38
Authors:  Fayang Zhou;  Anqi Wang;  Dan li;  Yitao Wang;  Ligen Lin
Favorite | View/Download:19/0 | TC[WOS]:12 TC[Scopus]:0 | Submit date:2018/10/31
Hepatic Stellate Cells  Liver Fibrosis  Penthorum Chinense Pursh  Pinocembrin  Silent Mating Type Information Regulation 2 Homolog 3  Sma- And Mad-related Proteins  
Novel Hsp90 inhibitor platycodin D disrupts Hsp90/Cdc37 complex and enhances the anticancer effect of mTOR inhibitor Journal article
TOXICOLOGY AND APPLIED PHARMACOLOGY, 2017,Volume: 330,Page: 65-73
Authors:  Li, Ting;  Chen, Xin;  Dai, Xiao-Yang;  Wei, Bin;  Weng, Qin-Jie;  Chen, Xiuping;  Ouyang, De-Fang;  Yan, Ru;  Huang, Zhang-Jian;  Jiang, Hu-Lin;  Zhu, Hong;  Lu, Jin-Jian
Favorite | View/Download:24/0 | TC[WOS]:13 TC[Scopus]:0 | Submit date:2018/10/30
Everolimus  Platycodin d  Hsp90  Cdc37  Egfr  Igf1r  
Osimertinib induces autophagy and apoptosis via reactive oxygen species generation in non-small cell lung cancer cells Journal article
TOXICOLOGY AND APPLIED PHARMACOLOGY, 2017,Volume: 321,Page: 18-26
Authors:  Tang, Zheng-Hai;  Cao, Wen-Xiang;  Su, Min-Xia;  Chen, Xiuping;  Lu, Jin-Jian
Favorite | View/Download:25/0 | TC[WOS]:21 TC[Scopus]:0 | Submit date:2018/10/30
Osimertinib  Azd9291  Autophagy  Apoptosis  Ros  
VEGFR tyrosine kinase inhibitor II (VRI) induced vascular insufficiency in zebrafish as a model for studying vascular toxicity and vascular preservation Journal article
Toxicology and Applied Pharmacology, 2014,Volume: 280,Issue: 3,Page: 408-420
Authors:  Li S.;  Dang Y.Y.;  Oi Lam Che G.;  Kwan Y.W.;  Chan S.W.;  Leung G.P.H.;  Lee S.M.Y.;  Hoi M.P.M.
Favorite | View/Download:10/0 | TC[WOS]:23 TC[Scopus]:0 | Submit date:2018/11/06
Cardiovascular Protective Agents  Cardiovascular Toxicity  Vascular Insufficiency  Zebrafish Model  
Cyanidin-3-glucoside inhibits UVB-induced oxidative damage and inflammation by regulating MAP kinase and NF-kappa B signaling pathways in SKH-1 hairless mice skin Journal article
TOXICOLOGY AND APPLIED PHARMACOLOGY, 2014,Volume: 280,Issue: 1,Page: 127-137
Authors:  Pratheeshkumar, Poyil;  Son, Young-Ok;  Wang, Xin;  Divya, Sasidharan Padmaja;  Joseph, Binoy;  Hitron, John Andrew;  Wang, Lei;  Kim, Donghern;  Yin, Yuanqin;  Roy, Ram Vinod;  Lu, Jian;  Zhang, Zhuo;  Wang, Yitao;  Shi, Xiang Lin
Favorite | View/Download:7/0 | TC[WOS]:36 TC[Scopus]:0 | Submit date:2018/11/01
Cyanidin-3-glucoside  Ultraviolet Radiation  Inflammation  Cox-2  Nf-kappa b  
Luteolin inhibits Cr(VI)-induced malignant cell transformation of human lung epithelial cells by targeting ROS mediated multiple cell signaling pathways Journal article
Toxicology and Applied Pharmacology, 2014,Volume: 281,Issue: 2,Page: 230
Authors:  Pratheeshkumar P.;  Son Y.-O.;  Divya S.P.;  Roy R.V.;  Hitron J.A.;  Wang L.;  Kim D.;  Dai J.;  Asha P.;  Zhang Z.;  Wang Y.;  Shi X.
Favorite | View/Download:7/0 | TC[WOS]:41 TC[Scopus]:0 | Submit date:2018/10/30
Angiogenesis  Carcinogenesis  Hexavalent Chromium  Inflammation  Luteolin  
Cyanidin-3-glucoside inhibits UVB-induced oxidative damage and inflammation by regulating MAP kinase and NF-κB signaling pathways in SKH-1 hairless mice skin Journal article
Toxicology and Applied Pharmacology, 2014,Volume: 280,Issue: 1,Page: 127
Authors:  Pratheeshkumar P.;  Son Y.-O.;  Wang X.;  Divya S.P.;  Joseph B.;  Hitron J.A.;  Wang L.;  Kim D.;  Yin Y.;  Roy R.V.;  Lu J.;  Zhang Z.;  Wang Y.;  Shi X.
Favorite | View/Download:6/0 | TC[WOS]:36 TC[Scopus]:0 | Submit date:2018/10/30
COX-2  Cyanidin-3-glucoside  Inflammation  NF-κB  Ultraviolet radiation