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γ-Mangostin alleviates liver fibrosis through Sirtuin 3-superoxide-high mobility group box 1 signaling axis Journal article
Toxicology and Applied Pharmacology, 2019,Volume: 363,Page: 142-153
Authors:  Wang A.;  Zhou F.;  Li D.;  Lu J.-J.;  Wang Y.;  Lin L.
Favorite | View/Download:26/0 | TC[WOS]:3 TC[Scopus]:0 | Submit date:2018/12/28
Fibrogenesis  Hmgb1  Liver Fibrosis  Sirtuin 3  Superoxide  Γ-mangostin  
gamma-Mangostin alleviates liver fibrosis through Sirtuin 3-superoxide-high mobility group box 1 signaling axis Journal article
TOXICOLOGY AND APPLIED PHARMACOLOGY, 2019,Volume: 363,Page: 142-153
Authors:  Wang A;  Zhou F;  Li D;  Lu JJ;  Wang Y;  Lin L
Favorite | View/Download:12/0 | TC[WOS]:3 TC[Scopus]:0 | Submit date:2020/03/20
Superoxide  Gamma-mangostin  Fibrogenesis  Sirtuin 3  Liver Fibrosis  Hmgb1  
Dihydronortanshinone, a natural product, alleviates LPS-induced inflammatory response through NF-κB, mitochondrial ROS, and MAPK pathways Journal article
Toxicology and Applied Pharmacology, 2018,Volume: 355,Page: 1-8
Authors:  Xiaxia Wu;  Hongwei Gao;  Ying Hou;  Jie Yu;  Wen Sun;  Ying Wang;  Xiaoyan Chen;  Yulin Feng;  Qiong-ming Xu;  Xiuping Chen
Favorite | View/Download:39/0 | TC[WOS]:12 TC[Scopus]:0 | Submit date:2018/12/28
Dihydronortanshinone  Inflammation  Lps  Macrophage  
Sodium tanshinone IIA sulfonate promotes endothelial integrity via regulating VE-cadherin dynamics and RhoA/ROCK-mediated cellular contractility and prevents atorvastatin-induced intracerebral hemorrhage in zebrafish Journal article
TOXICOLOGY AND APPLIED PHARMACOLOGY, 2018,Volume: 350,Page: 32-42
Authors:  Zhou, Zhong-Yan;  Huang, Bin;  Li, Shang;  Huang, Xiao-Hui;  Tang, Jing-Yi;  Kwan, Yiu Wa;  Hoi, Pui Man;  Lee, Simon Ming-Yuen
Favorite | View/Download:30/0 | TC[WOS]:5 TC[Scopus]:0 | Submit date:2018/10/30
Sodium Tanshinone Iia Sulfonate  Salvia Miltiorrhiza  Hemorrhagic Stroke  Atorvastatin  Rock  
Dihydrotanshinone I, a natural product, ameliorates DSS-induced experimental ulcerative colitis in mice Journal article
TOXICOLOGY AND APPLIED PHARMACOLOGY, 2018,Volume: 344,Page: 35-45
Authors:  Guo, Yanling;  Wu, Xiaxia;  Wu, Qin;  Lu, Yuanfu;  Shi, Jingshan;  Chen, Xiuping
Favorite | View/Download:26/0 | TC[WOS]:14 TC[Scopus]:0 | Submit date:2018/10/30
15,16-dihydrotanshinone i  Ulcerative Colitis  Inflammation  Necroptosis  
Pinocembrin from Penthorum chinense Pursh suppresses hepatic stellate cells activation through a unified SIRT3-TGF-beta-Smad signaling pathway Journal article
TOXICOLOGY AND APPLIED PHARMACOLOGY, 2018,Volume: 341,Page: 38-50
Authors:  Zhou, Fayang;  Wang, Anqi;  Li, Dan;  Wang, Yitao;  Lin, Ligen
View | Adobe PDF | Favorite | View/Download:512/17 | TC[WOS]:12 TC[Scopus]:0 | Submit date:2018/10/30
Liver Fibrosis  Hepatic Stellate Cells  Penthorum Chinense Pursh  Pinocembrin  Sma- And Mad-related Proteins  Silent Mating Type Information Regulation 2 Homolog 3  
Pinocembrin from Penthorum chinense Pursh suppresses hepatic stellate cells activation through a unified SIRT3-TGF-β-Smad signaling pathway Journal article
Toxicology and Applied Pharmacology, 2018,Volume: 341,Page: 38
Authors:  Fayang Zhou;  Anqi Wang;  Dan li;  Yitao Wang;  Ligen Lin
Favorite | View/Download:19/0 | TC[WOS]:12 TC[Scopus]:0 | Submit date:2018/10/31
Hepatic Stellate Cells  Liver Fibrosis  Penthorum Chinense Pursh  Pinocembrin  Silent Mating Type Information Regulation 2 Homolog 3  Sma- And Mad-related Proteins  
Novel Hsp90 inhibitor platycodin D disrupts Hsp90/Cdc37 complex and enhances the anticancer effect of mTOR inhibitor Journal article
TOXICOLOGY AND APPLIED PHARMACOLOGY, 2017,Volume: 330,Page: 65-73
Authors:  Li, Ting;  Chen, Xin;  Dai, Xiao-Yang;  Wei, Bin;  Weng, Qin-Jie;  Chen, Xiuping;  Ouyang, De-Fang;  Yan, Ru;  Huang, Zhang-Jian;  Jiang, Hu-Lin;  Zhu, Hong;  Lu, Jin-Jian
Favorite | View/Download:24/0 | TC[WOS]:13 TC[Scopus]:0 | Submit date:2018/10/30
Everolimus  Platycodin d  Hsp90  Cdc37  Egfr  Igf1r  
Osimertinib induces autophagy and apoptosis via reactive oxygen species generation in non-small cell lung cancer cells Journal article
TOXICOLOGY AND APPLIED PHARMACOLOGY, 2017,Volume: 321,Page: 18-26
Authors:  Tang, Zheng-Hai;  Cao, Wen-Xiang;  Su, Min-Xia;  Chen, Xiuping;  Lu, Jin-Jian
Favorite | View/Download:25/0 | TC[WOS]:21 TC[Scopus]:0 | Submit date:2018/10/30
Osimertinib  Azd9291  Autophagy  Apoptosis  Ros  
Cyanidin-3-glucoside inhibits UVB-induced oxidative damage and inflammation by regulating MAP kinase and NF-kappa B signaling pathways in SKH-1 hairless mice skin Journal article
TOXICOLOGY AND APPLIED PHARMACOLOGY, 2014,Volume: 280,Issue: 1,Page: 127-137
Authors:  Pratheeshkumar, Poyil;  Son, Young-Ok;  Wang, Xin;  Divya, Sasidharan Padmaja;  Joseph, Binoy;  Hitron, John Andrew;  Wang, Lei;  Kim, Donghern;  Yin, Yuanqin;  Roy, Ram Vinod;  Lu, Jian;  Zhang, Zhuo;  Wang, Yitao;  Shi, Xiang Lin
Favorite | View/Download:7/0 | TC[WOS]:36 TC[Scopus]:0 | Submit date:2018/11/01
Cyanidin-3-glucoside  Ultraviolet Radiation  Inflammation  Cox-2  Nf-kappa b