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Platycodin D triggers the extracellular release of programed death Ligand-1 in lung cancer cells Journal article
FOOD AND CHEMICAL TOXICOLOGY, 2019,Volume: 131
作者:  Mu-Yang Huang;  Xiao-Ming Jiang;  Yu-Lian Xu;  Luo-Wei Yuan;  Yu-Chi Chen;  Guozhen Cui;  Run-Yue Huang;  Bo Liu;  Yitao Wang;  Xiuping Chen;  Jin-Jian Lu
收藏  |  浏览/下载:7/0  |  提交时间:2019/11/22
Programmed Death Ligand-1  Platycodin d  Extracellular Release  Natural Products  Cancer  
Nagilactone E suppresses TGF-beta 1-induced epithelial-mesenchymal transition, migration and invasion in non-small cell lung cancer cells Journal article
PHYTOMEDICINE, 2019,Volume: 52,Page: 32-39
作者:  Le-Le Zhang;  Xiao-Ming Jiang;  Mu-Yang Huang;  Zhe-Ling Feng;  Xiuping Chen;  Yitao Wang;  Hua Li;  Ao Li;  Li-Gen Lin;  Jin-Jian Lu
收藏  |  浏览/下载:4/0  |  提交时间:2020/01/09
Nagilactone e  Tgf-β1  Epithelial-mesenchymal Transitio  Smad  
Toosendanin, a natural product, inhibited TGF-1-induced epithelial-mesenchymal transition through ERK/Snail pathway Journal article
PHYTOTHERAPY RESEARCH, 2018,Volume: 32,Issue: 10,Page: 2009-2020
作者:  Luo, Weiwei;  Liu, Xin;  Sun, Wen;  Lu, Jin-Jian;  Wang, Yitao;  Chen, Xiuping
浏览  |  Adobe PDF(2621Kb)  |  收藏  |  浏览/下载:357/28  |  提交时间:2018/10/30
Emt  Erk1/2  Snail  Lung Cancer  Toosendanin  
MLKL mediates apoptosis via a mutual regulation with PERK/eIF2 alpha pathway in response to reactive oxygen species generation Journal article
APOPTOSIS, 2018,Volume: 23,Issue: 9-10,Page: 521-531
作者:  Wen‑Xiang Cao;  Ting Li;  Zheng‑Hai Tang;  Le‑Le Zhang;  Zhao‑Yu Wang;  Xia Guo;  Min‑Xia Su;  Xiuping Chen;  Jin‑Jian Lu
收藏  |  浏览/下载:0/0  |  提交时间:2020/01/09
Mlkl  Eif2α  Ros  Apoptosis  Chelerythrine  
Downregulation of Cyclin B1 mediates nagilactone E-induced G2 phase cell cycle arrest in non-small cell lung cancer cells Journal article
EUROPEAN JOURNAL OF PHARMACOLOGY, 2018,Volume: 830,Page: 17-25
作者:  Zhang, Le-Le;  Feng, Zhe-Ling;  Su, Min-Xia;  Jiang, Xiao-Ming;  Chen, Xiuping;  Wang, Yitao;  Li, Ao;  Lin, Li-Gen;  Lu, Jin-Jian
浏览  |  Adobe PDF(3226Kb)  |  收藏  |  浏览/下载:184/23  |  提交时间:2018/10/30
Nagilactone e  Non-small Cell Lung Cancer  Cyclin B1  Cell Cycle  Apoptosis  
Diethyl blechnic, a novel natural product isolated from salvia miltiorrhiza bunge, inhibits doxorubicin-induced apoptosis by inhibiting ROS and activating JNK1/2 Journal article
International Journal of Molecular Sciences, 2018,Volume: 19,Issue: 6
作者:  Yu J.;  Gao H.;  Wu C.;  Xu Q.-M.;  Lu J.-J.;  Chen X.
收藏  |  浏览/下载:5/0  |  提交时间:2018/12/28
Cardiotoxicity  Diethyl Blechnic  Dox  Jnk1/2  Ros  
Induction of ferroptosis and mitochondrial dysfunction by oxidative stress in PC12 cells Journal article
SCIENTIFIC REPORTS, 2018,Volume: 8
作者:  Wu, Chuanhong;  Zhao, Wenwen;  Yu, Jie;  Li, Shaojing;  Lin, Ligen;  Chen, Xiuping
收藏  |  浏览/下载:16/0  |  提交时间:2018/10/30
Identification of a novel autophagic inhibitor cepharanthine to enhance the anti-cancer property of dacomitinib in non-small cell lung cancer Journal article
CANCER LETTERS, 2018,Volume: 412,Page: 1-9
作者:  Tang, Zheng-Hai;  Cao, Wen-Xiang;  Guo, Xia;  Dai, Xiao-Yang;  Lu, Jia-Hong;  Chen, Xiuping;  Zhu, Hong;  Lu, Jin-Jian
收藏  |  浏览/下载:14/0  |  提交时间:2018/10/30
Cepharanthine  Autophagy  Lysosome  Dacomitinib  Nsclc  
Increased expression of IRE1α associates with the resistant mechanism of osimertinib (AZD9291)-resistant non-small cell lung cancer HCC827/OSIR cells Journal article
Anti-Cancer Agents in Medicinal Chemistry, 2018,Volume: 18,Issue: 4,Page: 550-555
作者:  Tang Z.-H.;  Su M.-X.;  Guo X.;  Jiang X.-M.;  Jia L.;  Chen X.;  Lu J.-J.
收藏  |  浏览/下载:5/0  |  提交时间:2018/12/28
Azd9291  Egfr  Ire1α  Lune Cancer  Nsclc  Osimertinib  
In situ sequestration of endogenous PDGF-BB with an ECM-mimetic sponge for accelerated wound healing Journal article
BIOMATERIALS, 2017,Volume: 148,Page: 54-68
作者:  Li, Qiu;  Niu, Yiming;  Diao, Huajia;  Wang, Lintao;  Chen, Xiuping;  Wang, Yitao;  Dong, Lei;  Wang, Chunming
浏览  |  Adobe PDF(6957Kb)  |  收藏  |  浏览/下载:152/16  |  提交时间:2018/10/30
Biomimetic Scaffolds  Extraceilular Matrix  Polysaccharides  Growth Factors  Wound Healing