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N-terminal α-amino group modification of antibodies using a site-selective click chemistry method Journal article
mAbs, 2018,Volume: 10,Issue: 5,Page: 712-719
Authors:  Li D.-Z.;  Han B.-N.;  Wei R.;  Yao G.-Y.;  Chen Z.;  Liu J.;  Poon T.C.W.;  Su W.;  Zhu Z.;  Dimitrov D.S.;  Zhao Q.
Favorite  |  View/Download:3/0  |  Submit date:2019/01/16
Antibody  Antibody Engineering  Antibody-drug Conjugate  Click Chemistry  Site-specific Modification  
Facile preparation of stable PEG-functionalized quantum dots with glycine-enhanced photoluminescence and their application for screening of aflatoxin B-1 in herbs Journal article
SENSORS AND ACTUATORS B-CHEMICAL, 2018,Volume: 261,Page: 188-195
Authors:  Zhang, Lei;  Dou, Xiaowen;  Zhang, Cheng;  Ying, Guangyao;  Liu, Congmin;  Luo, Jiaoyang;  Li, Qian;  Li, Peng;  Wang, Yitao;  Yang, Meihua
View  |  Adobe PDF(2226Kb)  |  Favorite  |  View/Download:122/21  |  Submit date:2018/10/30
Quantum Dots  Mpeg-hs  Fluorescence Enhancement  Aflatoxin  Medicinal Herb  Flisa  
Isotopic graphene-isolated-Au-nanocrystals with cellular Raman-silent signals for cancer cell pattern recognition Journal article
CHEMICAL SCIENCE, 2018,Volume: 9,Issue: 10,Page: 2842-2849
Authors:  Zou, Yuxiu;  Huang, Siqi;  Liao, Yixin;  Zhu, Xupeng;  Chen, Yiqin;  Chen, Long;  Liu, Fang;  Hu, Xiaoxiao;  Tu, Haijun;  Zhang, Liang;  Liu, Zhangkun;  Chen, Zhuo;  Tan, Weihong
Favorite  |  View/Download:13/0  |  Submit date:2018/10/30
Structure-based identification of a NEDD8-activating enzyme inhibitor via drug repurposing Journal article
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018,Volume: 143,Page: 1021-1027
Authors:  Wu, Ke-Jia;  Zhong, Hai-Jing;  Li, Guodong;  Liu, Chenfu;  Wang, Hui-Min David;  Ma, Dik-Lung;  Leung, Chung-Hang
Favorite  |  View/Download:11/0  |  Submit date:2018/10/30
Drug repurposing  Mitoxantrone  NEDD8  Ubiquitin  
Engineering a protein-based nanoplatform as an antibacterial agent for light activated dual-modal photothermal and photodynamic therapy of infection in both the NIR i and II windows Journal article
Journal of Materials Chemistry B, 2018,Volume: 6,Issue: 5,Page: 732-739
Authors:  Gao D.Y.;  Ji X.;  Wang J.L.;  Wang Y.T.;  Li D.L.;  Liu Y.B.;  Chang K.W.;  Qu J.L.;  Zheng J.;  Yuan Z.
Favorite  |  View/Download:2/0  |  Submit date:2018/12/17
Cleavable Multifunctional Targeting Mixed Micelles with Sequential pH-Triggered TAT Peptide Activation for Improved Antihepatocellular Carcinoma Efficacy Journal article
MOLECULAR PHARMACEUTICS, 2017,Volume: 14,Issue: 11,Page: 3644-3659
Authors:  Zhang, Jinming;  Zheng, Yifeng;  Xie, Xi;  Wang, Lan;  Su, Ziren;  Wang, Yitao;  Leong, Kam W.;  Chen, Meiwan
View  |  Adobe PDF(2484Kb)  |  Favorite  |  View/Download:220/38  |  Submit date:2018/10/30
Tumor-targeting  Glycyrrhetinic Acid  Ph-sensitive  Tat Exposure  Mixed Micelles  
Recognition-then-Reaction Enables Site-Selective Bioconjugation to Proteins on Live-Cell Surfaces Journal article
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2017,Volume: 56,Issue: 39,Page: 11954-11957
Authors:  Cui, Cheng;  Zhang, Hui;  Wang, Ruowen;  Cansiz, Sena;  Pan, Xiaoshu;  Wan, Shuo;  Hou, Weijia;  Li, Long;  Chen, Meiwan;  Liu, Yuan;  Chen, Xigao;  Liu, Qiaoling;  Tan, Weihong
Favorite  |  View/Download:18/0  |  Submit date:2018/10/30
aptamer template  cell-surface modification  protein conjugation  site-selective  
Co-delivery of paclitaxel and tetrandrine via iRGD peptide conjugated lipid-polymer hybrid nanoparticles overcome multidrug resistance in cancer cells Journal article
SCIENTIFIC REPORTS, 2017,Volume: 7
Authors:  Zhang, Jinming;  Wang, Lu;  Chan, Hon Fai;  Xie, Wei;  Chen, Sheng;  He, Chengwei;  Wang, Yitao;  Chen, Meiwan
View  |  Adobe PDF(1919Kb)  |  Favorite  |  View/Download:119/5  |  Submit date:2018/10/30
Regioselective glucuronidation of the isoflavone calycosin by human liver microsomes and recombinant human UDP-glucuronosyltransferases Journal article
Chemico-Biological Interactions, 2014,Volume: 220,Page: 231-240
Authors:  Ruan J.-Q.;  Yan R.
Favorite  |  View/Download:4/0  |  Submit date:2018/12/28
Calycosin  Glucuronidation  Metabolism  Regioselectivity  Udp-glucuronosyltransferases  
Metabolic characterization of (+/-)-praeruptorin A in vitro and in vivo by high performance liquid chromatography coupled with hybrid triple quadrupole-linear ion trap mass spectrometry and time-of-fl Journal article
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2014,Volume: 90,Issue: 5,Page: 98-110
Authors:  Song, Yue-Lin;  Jing, Wang-Hui;  Yan, Ru;  Wang, Yi-Tao
View  |  Adobe PDF(3404Kb)  |  Favorite  |  View/Download:55/7  |  Submit date:2018/11/01
(+/-)-praeruptorin a  Metabolism  Lightsight (Tm) Software  In Vivo  Peucedani Radix