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Potent Protection Against MPP+ -Induced Neurotoxicity via Activating Transcription Factor MEF2D by a Novel Derivative of Naturally Occurring Danshensu/Tetramethylpyrazine Journal article
NEUROMOLECULAR MEDICINE, 2016,Volume: 18,Issue: 4,Page: 561-572
Authors:  Shengquan Hu;  Liang Wang;  Shinghung Mak;  Zaijun Zhang;  Daping Xu;  Haitao Li;  Yide Li;  Yuanjia Hu;  Simon Ming Yuen Lee;  Yuqiang Wang;  Yifan Han
Favorite | View/Download:246/0 | TC[WOS]:5 TC[Scopus]:5 | Submit date:2020/01/16
Parkinson’s Disease  Mef2d  Neuroprotection  
Neuroprotection against glutamate-induced excitotoxicity and induction of neurite outgrowth by T-006, a novel multifunctional derivative of tetramethylpyrazine in neuronal cell models Journal article
Neurochemistry International, 2016,Volume: 99,Page: 194-205
Authors:  Xu D.;  Chen H.;  Mak S.;  Hu S.;  Tsim K.W.K.;  Hu Y.;  Sun Y.;  Zhang G.;  Wang Y.;  Zhang Z.;  Han Y.
Favorite | View/Download:12/0 | TC[WOS]:9 TC[Scopus]:13 | Submit date:2018/12/28
Alzheimer's Disease  Excitotoxicity  Neurite Outgrowth  Neuroprotection  Tetramethylpyrazine Derivative  
A New Danshensu Derivative Protects Against 6-Hydroxydopamine-Induced Neurotoxicity in Vitro and in Vivo Journal article
American Journal of Chinese Medicine, 2016,Volume: 44,Issue: 7,Page: 1349-1361
Authors:  Guozhen Cui;  Luchen Shan;  Yang Chen;  Hefeng Zhou;  Yuqiang Wang;  Simon Ming-Yuen Lee
Favorite | View/Download:10/0 | TC[WOS]:4 TC[Scopus]:4 | Submit date:2018/11/06
Anti-inflammation  Anti-oxidation  Danshensu Derivative  Neuroprotection  
Artemisinin conferred ERK mediated neuroprotection to PC12 cells and cortical neurons exposed to sodium nitroprusside-induced oxidative insult Journal article
Free Radical Biology and Medicine, 2016,Volume: 97,Page: 158-167
Authors:  Zheng W.;  Chong C.-M.;  Wang H.;  Zhou X.;  Zhang L.;  Wang R.;  Meng Q.;  Lazarovici P.;  Fang J.
Favorite | View/Download:15/0 | TC[WOS]:23 TC[Scopus]:30 | Submit date:2018/12/21
Artemisinin  Erk1/2  Neuroprotection  Pc12 Cells  Sodium Nitroprusside  
No synergism between bis(propyl)-cognitin and rasagiline on protecting dopaminergic neurons in Parkinson's disease mice Journal article
NEURAL REGENERATION RESEARCH, 2016,Volume: 11,Issue: 8,Page: 1339-1346
Authors:  Cheng-you Zheng;  Bao-jian Guo;  Wei Cai;  Wei Cui;  Shing-hung Mak;  Yu-qiang Wang;  Simon Ming-yuen Lee;  Yi-fan Han;  Zai-jun Zhang
Favorite | View/Download:246/0 | TC[WOS]:1 TC[Scopus]:0 | Submit date:2020/01/16
Nerve Regeneration  Parkinson's Disease  Bis(Propyl)-cognitin  Rasagiline  Monoamine Oxidase b  Dopamine  Multitarget  Synergism  Neuroprotection  Neural Regeneration  
Multifunction of chrysin in Parkinson's model: Anti-neuronal apoptosis, neuroprotection via activation of MEF2D, and inhibition of monoamine oxidase-B Journal article
Journal of Agricultural and Food Chemistry, 2016,Volume: 64,Issue: 26,Page: 5324-5333
Authors:  Baojian Guo;  Chengyou Zheng;  Wei Cai;  Jiehong Cheng;  Hongyu Wang;  Haitao Li;  Yewei Sun;  Wei Cui;  Yuqiang Wang;  Yifan Han;  Simon Ming-Yuen Lee;  Zaijun Zhang
Favorite | View/Download:23/0 | TC[WOS]:11 TC[Scopus]:18 | Submit date:2018/11/06
Chrysin  Mao-b  Mef2d  Neuroprotection  Parkinson's Disease  
Increased production of omega-3 fatty acids protects retinal ganglion cells after optic nerve injury in mice Journal article
Experimental Eye Research, 2016,Volume: 148,Page: 90-96
Authors:  Peng S.;  Shi Z.;  Su H.;  So K.-F.;  Cui Q.
Favorite | View/Download:12/0 | TC[WOS]:8 TC[Scopus]:8 | Submit date:2018/12/28
Camp  Erk1/2 Pathway  Omega-3 Fatty Acids  Optic Nerve Injury  Retinal Ganglion Cell  Survival  
Genipin derivatives protect RGC-5 from sodium Nitroprusside-induced Nitrosative stress Journal article
International Journal of Molecular Sciences, 2016,Volume: 17,Issue: 1
Authors:  Wang R.;  Zhao J.;  Zhang L.;  Peng L.;  Zhang X.;  Zheng W.;  Chen H.
Favorite | View/Download:6/0 | TC[WOS]:0 TC[Scopus]:4 | Submit date:2018/12/21
Apoptosis  Genipin  Neurodegeneration  Neuroprotection  Nitric oxide synthase  NO neurotoxicity  
Protection against oxygen-glucose deprivation/reperfusion injury in cortical neurons by combining omega-3 polyunsaturated acid with Lyciumbarbarum polysaccharide Journal article
Nutrients, 2016,Volume: 8,Issue: 1
Authors:  Shi Z.;  Wu D.;  Yao J.-P.;  Yao X.;  Huang Z.;  Li P.;  Wan J.-B.;  He C.;  Su H.
Favorite | View/Download:12/0 | TC[WOS]:7 TC[Scopus]:9 | Submit date:2018/12/28
Ca2++  Cortical Neurons  Dha  Lbp  Neuroprotection  Ogd/r  Trk-b  
Lithium ions attenuate serum-deprivation-induced apoptosis in PC12 cells through regulation of the Akt/FoxO1 signaling pathways Journal article
Psychopharmacology, 2016,Volume: 233,Issue: 5,Page: 785
Authors:  Zeng Z.;  Wang H.;  Shang F.;  Zhou L.;  Little P.J.;  Quirion R.;  Zheng W.
Favorite | View/Download:12/0 | TC[WOS]:16 TC[Scopus]:16 | Submit date:2018/10/30
Apoptosis  Lithium  Neuroprotection  Pi3k/akt/foxo1  Serum Deprivation