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Serially coupled reversed phase-hydrophilic interaction liquid chromatography-tailored multiple reaction monitoring, a fit-for-purpose tool for large-scale targeted metabolomics of medicinal bile Journal article
ANALYTICA CHIMICA ACTA, 2018,Volume: 1037,Page: 119-129
作者:  Song, Qingqing;  Liu, Wenjing;  Chen, Xiaojia;  Li, Jun;  Li, Peng;  Yang, Fengqing;  Wang, Yitao;  Song, Yuelin;  Tu, Pengfei
Adobe PDF(1652Kb)  |  收藏  |  浏览/下载:264/3  |  提交时间:2018/10/30
Large-scale Targeted Metabolomics  Serially Coupled Rplc-hilic  Tailored Multiple Reaction Monitoring  Medicinal Bile  Bile Acids  
Chemoselective detection of alkyl halides via an iridium(III) luminescent probe Journal article
DYES AND PIGMENTS, 2018,Volume: 159,Page: 479-482
作者:  Wu, Chun;  Liu, Jin-Biao;  Li, Guodong;  Wong, Suk-Yu;  Han, Quan-Bin;  Leung, Chung-Hang;  Ma, Dik-Lung
浏览  |  Adobe PDF(687Kb)  |  收藏  |  浏览/下载:157/17  |  提交时间:2018/10/30
Alkyl Halides  Iridium  Chemosensor  
Inhibition of lung cancer by 2-methoxy-6-acetyl-7-methyljuglone (MAM) through induction of necroptosis by targeting receptor-interacting protein 1 (RIP1) Journal article
Antioxidants & Redox Signaling, 2018,Volume: 0,Issue: JA
作者:  Sun W;  Yu J;  Gao H;  Wu X;  Wang S;  Hou Y;  Lu JJ;  Chen X
收藏  |  浏览/下载:6/0  |  提交时间:2019/01/16
Dichloroacetophenones targeting at pyruvate dehydrogenase kinase 1 with improved selectivity and antiproliferative activity: Synthesis and structure-activity relationships Journal article
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2018,Volume: 28,Issue: 21,Page: 3441-3445
作者:  Zhang, Shao-Lin;  Yang, Zheng;  Hu, Xiaohui;  Tam, Kin Yip
收藏  |  浏览/下载:12/0  |  提交时间:2018/10/30
Pyruvate dehydrogenase kinase  Pyruvate dehydrogenase complex  Antiproliferative activity  Dichloroacetophenone  Kinase inhibition  
G-Quadruplex-Based Nanoscale Coordination Polymers to Modulate Tumor Hypoxia and Achieve Nuclear-Targeted Drug Delivery for Enhanced Photodynamic Therapy Journal article
Nano Letters, 2018,Volume: 18,Issue: 11,Page: 6867-6875
作者:  Yang Y.;  Zhu W.;  Feng L.;  Chao Y.;  Yi X.;  Dong Z.;  Yang K.;  Tan W.;  Liu Z.;  Chen M.W
收藏  |  浏览/下载:6/0  |  提交时间:2018/12/27
Dna Nanostructure  G-quadruplex  Nanoscale Coordination-polymers  Ncps  Photodynamic Therapy  Tumor Hypoxia  
Inhibition of pyruvate dehydrogenase kinase 1 enhances the anti-cancer effect of EGFR tyrosine kinase inhibitors in non-small cell lung cancer Journal article
EUROPEAN JOURNAL OF PHARMACOLOGY, 2018,Volume: 838,Page: 41-52
作者:  Yang, Zheng;  Zhang, Shao-Lin;  Hu, Xiaohui;  Tam, Kin Yip
收藏  |  浏览/下载:13/0  |  提交时间:2018/10/30
Dichloroacetophenone  Epidermal growth factor receptor  Tyrosine kinase inhibitor  Synergism  Hypoxia  Oxidative phosphorylation  
Fluidic shear stress increases the anti-cancer effects of ROS-generating drugs in circulating tumor cells Journal article
BREAST CANCER RESEARCH AND TREATMENT, 2018,Volume: 172,Issue: 2,Page: 297-312
作者:  Regmi S;  Fung TS;  Lim S;  Luo KQ
收藏  |  浏览/下载:7/0  |  提交时间:2018/10/30
Circulating Tumor Cells  Shear Stress  Reactive Oxygen Species  Apoptosis  Anti-cancer Drugs  Doxorubicin  
Chaetominine induces cell cycle arrest in human leukemia K562 and colon cancer SW1116 cells Journal article
ONCOLOGY LETTERS, 2018,Volume: 16,Issue: 4,Page: 4671-4678
作者:  Yao, Jingyun;  Xiao, Jianbo;  Wei, Xing;  Lu, Yanhua
收藏  |  浏览/下载:15/0  |  提交时间:2018/10/30
cell cycle arrest  cyclin  cyclin-dependent kinase  chaetominine  K562 cells  SW1116 cells  
Selective Inhibition of Lysine-Specific Demethylase 5A (KDM5A) Using a Rhodium(III) Complex for Triple-Negative Breast Cancer Therapy Journal article
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2018,Volume: 57,Issue: 40,Page: 13091-13095
作者:  Yang, Guan-Jun;  Wang, Wanhe;  Mok, Simon Wing Fai;  Wu, Chun;  Law, Betty Yuen Kwan;  Miao, Xiang-Min;  Wu, Ke-Jia;  Zhong, Hai-Jing;  Wong, Chun-Yuen;  Wong, Vincent Kam Wai;  Ma, Dik-Lung;  Leung, Chung-Hang
收藏  |  浏览/下载:28/0  |  提交时间:2018/10/30
Drug Discovery  Epigenetics  Medicinal Chemistry  Triple-negative Breast Cancer  
Andrographolide derivative as STAT3 inhibitor that protects acute liver damage in mice Journal article
BIOORGANIC & MEDICINAL CHEMISTRY, 2018,Volume: 26,Issue: 18,Page: 5053-5061
作者:  Chen, Shao-Ru;  Li, Feng;  Ding, Mo-Yu;  Wang, Decai;  Zhao, Qi;  Wang, Yitao;  Zhou, Guo-Chun;  Wang, Ying
浏览  |  Adobe PDF(2009Kb)  |  收藏  |  浏览/下载:347/49  |  提交时间:2018/10/30
Andrographolide  Stat3 Inhibitor  Acute Liver Damage  Inflammation