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Substantial Neuroprotective and Neurite Outgrowth-Promoting Activities by Bis(propyl)-cognitin via the Activation of Alpha7-nAChR, a Promising Anti-Alzheimer's Dimer Journal article
ACS Chemical Neuroscience, 2015,Volume: 6,Issue: 9,Page: 1536-1545
Authors:  Hu S.;  Cui W.;  Mak S.;  Xu D.;  Hu Y.;  Tang J.;  Choi C.;  Lee M.;  Pang Y.;  Han Y.
Favorite  |  View/Download:5/0  |  Submit date:2018/11/06
alpha7-nicotinic acetylcholine receptor  Alzheimer's disease  bis(propyl)-cognitin  extracellular signal-regulated kinase  neurite outgrowth  neuroprotection  
Robust Neuritogenesis-Promoting Activity by Bis(heptyl)-Cognitin Through the Activation of alpha7-Nicotinic Acetylcholine Receptor/ERK Pathway Journal article
CNS Neuroscience and Therapeutics, 2015,Volume: 21,Issue: 6,Page: 520-529
Authors:  Hu S.-Q.;  Cui W.;  Mak S.-H.;  Choi C.-L.;  Hu Y.-J.;  Li G.;  Tsim K.W.-K.;  Pang Y.-P.;  Han Y.-F.
Favorite  |  View/Download:1/0  |  Submit date:2018/12/28
Alpha7-nicotinic acetylcholine receptor  Bis(heptyl)-cognitin  Extracellular signal-regulated kinase  Neurite outgrowth  Neurodegenerative disorders  
Soluble NgR fusion protein modulates the proliferation of neural progenitor cells via the notch pathway Journal article
Neurochemical Research, 2011,Volume: 36,Issue: 12,Page: 2363-2372
Authors:  Li X.;  Su H.;  Fu Q.-L.;  Guo J.;  Lee D.H.S.;  So K.-F.;  Wu W.
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Myelin-associated glycoprotein  Nogo-66 receptor  NogoA  Notch1  Rat neural progenitor cells  
Oxadiazole derivatives as a novel class of antimitotic agents: Synthesis, inhibition of tubulin polymerization, and activity in tumor cell lines Journal article
Bioorganic and Medicinal Chemistry Letters, 2006,Volume: 16,Issue: 5,Page: 1191-1196
Authors:  Ouyang X.;  Piatnitski E.L.;  Pattaropong V.;  Chen X.;  He H.-Y.;  Kiselyov A.S.;  Velankar A.;  Kawakami J.;  Labelle M.;  Smith II L.;  Lohman J.;  Lee S.P.;  Malikzay A.;  Fleming J.;  Gerlak J.;  Wang Y.;  Rosler R.L.;  Zhou K.;  Mitelman S.;  Camara M.;  Surguladze D.;  Doody J.F.;  Tuma M.C.
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1,3,4-Oxadiazole  Antimitotic agent  Multiple-drug resistance  Tubulin polymerization inhibitor  
Synthesis and structure-activity relationships of 1,2,4-triazoles as a novel class of potent tubulin polymerization inhibitors Journal article
Bioorganic and Medicinal Chemistry Letters, 2005,Volume: 15,Issue: 23,Page: 5154-5159
Authors:  Ouyang X.;  Chen X.;  Piatnitski E.L.;  Kiselyov A.S.;  He H.-Y.;  Mao Y.;  Pattaropong V.;  Yu Y.;  Kim K.H.;  Kincaid J.;  Smith II L.;  Wong W.C.;  Lee S.P.;  Milligan D.L.;  Malikzay A.;  Fleming J.;  Gerlak J.;  Deevi D.;  Doody J.F.;  Chiang H.-H.;  Patel S.N.;  Wang Y.;  Rolser R.L.;  Kussie P.;  Labelle M.;  Tuma M.C.
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1,2,4-Triazole  Antimitotic  Tubulin inhibitor  Tubulin polymerization  Tumor vasculature  Vascular disrupting agent