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Nitazoxanide, an anti-parasitic drug, efficiently ameliorates learning and memory impairments in AD model mice Journal article
ACTA PHARMACOLOGICA SINICA, 2019,Volume: 40,Issue: 10,Page: 1279-1291
Authors:  Lei Fan;  Xiao-xia Qiu;  Zhi-yuan Zhu;  Jian-lu Lv;  Jian Lu;  Fei Mao;  Jin Zhu;  Jia-ying Wang;  Xiao-wei Guan;  Jing Chen;  Jin Ren;  Ji-ming Ye;  Yong-hua Zhao;  Jian Li;  Xu Shen
Favorite | View/Download:16/0 | TC[WOS]:2 TC[Scopus]:0 | Submit date:2020/04/14
App/ps1 Transgenic Mice  Alzheimer’s Disease  Autophagy  Inflammation  Nitazoxanide  
SLOH, a carbazole-based fluorophore, mitigates neuropathology and behavioral impairment in the triple-transgenic mouse model of Alzheimer's disease Journal article
NEUROPHARMACOLOGY, 2018,Volume: 131,Page: 351-363
Authors:  Wu, Xiaoli;  Kosaraju, Jayasankar;  Zhou, Wei;  Tam, Kin Yip
Favorite | View/Download:16/0 | TC[WOS]:4 TC[Scopus]:0 | Submit date:2018/10/31
Amyloid beta  Aggregation  Alzheimer's disease  3xTg-AD  Neuroprotection  SH-SY5Y  
SLM, a novel carbazole-based fluorophore attenuates okadaic acid-induced tau hyperphosphorylation via down-regulating GSK-3 beta activity in SH-SY5Y cells Conference paper
Authors:  Wu, Xiaoli;  Kosaraju, Jayasankar;  Tam, Kin Yip
Favorite | View/Download:7/0 | TC[WOS]:8 TC[Scopus]:0 | Submit date:2018/10/30
Tau hyperphosphorylation  Alzheimer's disease  SLM  Okadaic acid  Glycogen synthase kinase-3 beta  
SLM, a novel carbazole-based fluorophore attenuates okadaic acid-induced tau hyperphosphorylation via down-regulating GSK-3β activity in SH-SY5Y cells Journal article
European Journal of Pharmaceutical Sciences, 2017,Volume: 110,Page: 101-108
Authors:  Wu X.;  Kosaraju J.;  Tam K.Y.
Favorite | View/Download:23/0 | TC[WOS]:8 TC[Scopus]:0 | Submit date:2018/12/18
Alzheimer's Disease  Glycogen Synthase Kinase-3β  Okadaic Acid  Slm  Tau Hyperphosphorylation  
Chemical and Physical Approaches for the Treatment of Alzheimer's Disease Journal article
ADMET & DMPK, 2015,Volume: 3,Issue: 3,Page: 216-234
Authors:  Jing Li;  WeiZhou;  Xiaoli Wu;  KinTam
Favorite | View/Download:4/0 | TC[WOS]:1 TC[Scopus]:0 | Submit date:2019/01/07
Alzheimer’s Disease  Β-amyloid Peptide  Tau Protein  Pharmacological Strategies  Deep Brain Stimulation  Neurobiological Pathogenesis  
Multi-Target Drugs: The Trend of Drug Research and Development Journal article
PLOS ONE, 2012,Volume: 7,Issue: 6,Page: 30-46
Authors:  Lu, JJ (Lu, Jin-Jian);  Pan, W (Pan, Wei);  Hu, YJ (Hu, Yuan-Jia);  Wang, YT (Wang, Yi-Tao
View | Adobe PDF | Favorite | View/Download:499/42 | TC[WOS]:138 TC[Scopus]:0 | Submit date:2018/11/01
Cancer-therapy  Alzheimers-disease  Parkinsons-disease  Attractive Target  Natural-products  b Inhibitors  Discovery  Atherosclerosis  Acetylcholinesterase  Proliferation  
Berberine Alkaloid as a Medicament for Prophylaxis and Treatment of Alzheimer’s Disease Patent
专利类型: 发明专利, 专利号: US20130237556A1,
Authors:  Min LI;  Siva Sundara Kumar DURAIRAJAN;  Liangfeng LIU;  Jiahong LU,
Favorite | View/Download:10/0 | TC[WOS]:0 TC[Scopus]:0 | Submit date:2019/01/31