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A native-like bispecific antibody suppresses the inflammatory cytokine response by simultaneously neutralizing tumor necrosis factor-alpha and interleukin-17A Journal article
ONCOTARGET, 2017,Volume: 8,Issue: 47,Page: 81860-81872
Authors:  Xu, Tianshu;  Ying, Tianlei;  Wang, Lili;  Zhang, Xiaohua Douglas;  Wang, Ying;  Kang, Lishan;  Huang, Tao;  Cheng, Liang;  Wang, Liping;  Zhao, Qi
Favorite  |  View/Download:10/0  |  Submit date:2018/10/30
Bispecific Antibody  Fc Heterodimerization  Tnf-alpha  Il-17  Rheumatoid Arthritis  Immunology And Microbiology Section  Immune Response  Immunity  
Development of a specific affinity-matured exosite inhibitor to MT1-MMP that efficiently inhibits tumor cell invasion in vitro and metastasis in vivo Journal article
Oncotarget, 2016,Volume: 7,Issue: 13,Page: 16773-16792
Authors:  Botkjaer K.A.;  Kwok H.F.;  Terp M.G.;  Karatt-Vellatt A.;  Santamaria S.;  McCafferty J.;  Andreasen P.A.;  Itoh Y.;  Ditzel H.J.;  Murphy G.
Favorite  |  View/Download:5/0  |  Submit date:2018/12/19
Antibody  In Vivo targetIng  Metastasis  Mt1-mmp  Non-catalytic Sites  
Targeting the sheddase activity of Adam17 by an Anti-ADAM17 antibody D1(A12) inhibits head and neck squamous cell carcinoma cell proliferation and motility via blockage of bradykinin induced HERs transactivation Journal article
International Journal of Biological Sciences, 2014,Volume: 10,Issue: 7,Page: 702-714
Authors:  Huang Y.;  Benaich N.;  Tape C.;  Kwok H.F.;  Murphy G.
Favorite  |  View/Download:4/0  |  Submit date:2018/12/19
Adam17  Cell Proliferation And Motility  Her Receptor And ligAnds  Inhibitory Antibody