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Inhibition of lung cancer by 2-methoxy-6-acetyl-7-methyljuglone (MAM) through induction of necroptosis by targeting receptor-interacting protein 1 (RIP1) Journal article
Antioxidants & Redox Signaling, 2018,Volume: 0,Issue: JA
Authors:  Sun W;  Yu J;  Gao H;  Wu X;  Wang S;  Hou Y;  Lu JJ;  Chen X
Favorite  |  View/Download:3/0  |  Submit date:2019/01/16
Toosendanin, a natural product, inhibited TGF-1-induced epithelial-mesenchymal transition through ERK/Snail pathway Journal article
PHYTOTHERAPY RESEARCH, 2018,Volume: 32,Issue: 10,Page: 2009-2020
Authors:  Luo, Weiwei;  Liu, Xin;  Sun, Wen;  Lu, Jin-Jian;  Wang, Yitao;  Chen, Xiuping
View  |  Adobe PDF(2621Kb)  |  Favorite  |  View/Download:193/21  |  Submit date:2018/10/30
Emt  Erk1/2  Snail  Lung Cancer  Toosendanin  
Downregulation of Cyclin B1 mediates nagilactone E-induced G2 phase cell cycle arrest in non-small cell lung cancer cells Journal article
EUROPEAN JOURNAL OF PHARMACOLOGY, 2018,Volume: 830,Page: 17-25
Authors:  Zhang, Le-Le;  Feng, Zhe-Ling;  Su, Min-Xia;  Jiang, Xiao-Ming;  Chen, Xiuping;  Wang, Yitao;  Li, Ao;  Lin, Li-Gen;  Lu, Jin-Jian
View  |  Adobe PDF(3226Kb)  |  Favorite  |  View/Download:124/17  |  Submit date:2018/10/30
Nagilactone e  Non-small Cell Lung Cancer  Cyclin B1  Cell Cycle  Apoptosis  
Osimertinib resistance in non-small cell lung cancer: Mechanisms and therapeutic strategies Journal article
CANCER LETTERS, 2018,Volume: 420,Page: 242-246
Authors:  Tang, Zheng-Hai;  Lu, Jin-Jian
Favorite  |  View/Download:8/0  |  Submit date:2018/10/30
Osimertinib  Azd9291  Egfr Tki  Resistant Mechanisms  Therapeutic Strategies  
Increased expression of IRE1α associates with the resistant mechanism of osimertinib (AZD9291)-resistant non-small cell lung cancer HCC827/OSIR cells Journal article
Anti-Cancer Agents in Medicinal Chemistry, 2018,Volume: 18,Issue: 4,Page: 550-555
Authors:  Tang Z.-H.;  Su M.-X.;  Guo X.;  Jiang X.-M.;  Jia L.;  Chen X.;  Lu J.-J.
Favorite  |  View/Download:3/0  |  Submit date:2018/12/28
Azd9291  Egfr  Ire1α  Lune Cancer  Nsclc  Osimertinib  
Garcinone E induces apoptosis and inhibits migration and invasion in ovarian cancer cells Journal article
SCIENTIFIC REPORTS, 2017,Volume: 7
Authors:  Xu, Xiao-Huang;  Liu, Qian-Yu;  Li, Ting;  Liu, Jian-Lin;  Chen, Xin;  Huang, Li;  Qiang, Wen-An;  Chen, Xiuping;  Wang, Yitao;  Lin, Li-Gen;  Lu, Jin-Jian
View  |  Adobe PDF(5330Kb)  |  Favorite  |  View/Download:86/9  |  Submit date:2018/10/30
Natural products to prevent drug resistance in cancer chemotherapy: a review Journal article
ANNALS OF THE NEW YORK ACADEMY OF SCIENCES, 2017,Volume: 1401,Issue: 1,Page: 19-27
Authors:  Yuan, Renyikun;  Hou, Ying;  Sun, Wen;  Yu, Jie;  Liu, Xin;  Niu, Yanan;  Lu, Jin-Jian;  Chen, Xiuping
Favorite  |  View/Download:10/0  |  Submit date:2018/10/30
Drug Resistance  Cancer  Natural Products  Nonapoptotic Cell Death  
Osthole inhibited TGF beta-induced epithelial-mesenchymal transition (EMT) by suppressing NF-kappa B mediated Snail activation in lung cancer A549 cells Journal article
CELL ADHESION & MIGRATION, 2017,Volume: 11,Issue: 5-6,Page: 464-475
Authors:  Feng, Haitao;  Lu, Jin-Jian;  Wang, Yitao;  Pei, Lixia;  Chen, Xiuping
View  |  Adobe PDF(1506Kb)  |  Favorite  |  View/Download:55/6  |  Submit date:2018/10/30
Emt  Nf-kappa b  Osthole Snail  Tgf-beta 1  
Characterization of osimertinib (AZD9291)-resistant non-small cell lung cancer NCI-H1975/OSIR cell line Journal article
Oncotarget, 2016,Volume: 7,Issue: 49,Page: 81598-81610
Authors:  Tang Z.-H.;  Jiang X.-M.;  Guo X.;  Fong C.M.V.;  Chen X.;  Lu J.-J.
Favorite  |  View/Download:2/0  |  Submit date:2018/12/28
Azd9291  Egfr  Navitoclax  Nsclc  Osimertinib  
Saponins from Chinese Medicines as Anticancer Agents Journal article
Molecules, 2016,Volume: 21,Issue: 10,Page: 1326
Authors:  Xu XH;  Li T;  Fong CMV;  Chen XP;  Chen XJ;  Wang YT;  Huang MQ;  Lu JJ
Favorite  |  View/Download:4/0  |  Submit date:2018/11/23
Triterpenoid Saponins  Steroid Saponins  Mechanism  Target  Cancer