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Multiple noncovalent interactions mediated one-pot therapeutic assemblies for the effective treatment of atherosclerosis Journal article
Journal of Materials Chemistry B, 2015,Volume: 3,Issue: 37,Page: 7355-7365
Authors:  Dou Y.;  Zhang X.;  Xu X.;  Zhou X.;  Han S.;  Wang R.;  Su M.;  Li X.;  Zhang J.
Favorite  |  View/Download:1/0  |  Submit date:2018/11/06
NFκB up-regulation of glucose transporter 3 is essential for hyperactive mammalian target of rapamycin-induced aerobic glycolysis and tumor growth Journal article
Cancer Letters, 2015,Volume: 359,Issue: 1,Page: 97-106
Authors:  Zha X.;  Hu Z.;  Ji S.;  Jin F.;  Jiang K.;  Li C.;  Zhao P.;  Tu Z.;  Chen X.;  Di L.;  Zhou H.;  Zhang H.
Favorite  |  View/Download:0/0  |  Submit date:2018/12/21
Aerobic glycolysis  Glut3  MTOR  NFκB  Tumorigenesis  
Deficiency of Akt1, but not Akt2, attenuates the development of pulmonary hypertension Journal article
American Journal of Physiology - Lung Cellular and Molecular Physiology, 2015,Volume: 308,Issue: 2,Page: L208-L220
Authors:  Tang H.;  Chen J.;  Fraidenburg D.R.;  Song S.;  Sysol J.R.;  Drennan A.R.;  Offermanns S.;  Ye R.D.;  Bonini M.G.;  Minshall R.D.;  Garcia J.G.N.;  Machado R.F.;  Makino A.;  Yuan J.X.-J.
Favorite  |  View/Download:1/0  |  Submit date:2018/11/07
Akt/mammalian target of rapamycin signaling  Hypoxia  Pulmonary vascular remodeling  Smooth muscle cell proliferation  
Peptidyl-prolyl isomerases: Functionality and potential therapeutic targets in cardiovascular disease Journal article
Clinical and Experimental Pharmacology and Physiology, 2015,Volume: 42,Issue: 2,Page: 117-124
Authors:  Rostam M.A.;  Piva T.J.;  Rezaei H.B.;  Kamato D.;  Little P.J.;  Zheng W.;  Osman N.
Favorite  |  View/Download:0/0  |  Submit date:2018/12/21
Atherosclerosis  Cardiovascular disease  Peptidyl-prolyl isomerase  Pin1  
Antifungal drug itraconazole targets VDAC1 to modulate the AMPK/mTOR signaling axis in endothelial cells Journal article
Proceedings of the National Academy of Sciences of the United States of America, 2015,Volume: 112,Issue: 52,Page: E7276
Authors:  Head S.A.;  Shi W.;  Zhao L.;  Gorshkov K.;  Pasunooti K.;  Chen Y.;  Deng Z.;  Li R.-J.;  Shim J.S.;  Tan W.;  Hartung T.;  Zhang J.;  Zhao Y.;  Colombini M.;  Liu J.O.
Favorite  |  View/Download:3/0  |  Submit date:2018/10/30
Angiogenesis  Itraconazole  Metabolism  Mitochondria  VDAC1  
A dual-specific anti-IGF-1/IGF-2 human monoclonal antibody alone and in combination with temsirolimus for therapy of neuroblastoma Journal article
International Journal of Cancer, 2015,Volume: 137,Issue: 9,Page: 2243-2252
Authors:  Zhao Q.;  Tran H.;  Dimitrov D.S.;  Cheung N.-K.V.
Favorite  |  View/Download:1/0  |  Submit date:2019/01/16
chemotherapy  IGF-1  IGF-2  neuroblastoma  temsirolimus  
The antifungal drug itraconazole targets VDAC1 to modulate the AMPK/mTOR signaling axis in endothelial cells Journal article
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2015,Volume: 112,Issue: 52,Page: E7276-E7285
Authors:  Sarah A. Head;  Wei Shi;  Liang Zhao;  Kirill Gorshkov;  Kalyan Pasunooti;  Yue Chen;  Zhiyou Deng;  Ruo-jing Li;  Joong Sup Shim;  Wenzhi Tan;  Thomas Hartung;  Jin Zhang;  Yingming Zhao;  Marco Colombini;  Jun O. Liu
Favorite  |  View/Download:3/0  |  Submit date:2019/01/24
Angiogenesis  Mitochondria  Metabolism  Itraconazole  Vdac1  
Inhibition of angiogenesis by selective estrogen receptor modulators through blockade of cholesterol trafficking rather than estrogen receptor antagonism Journal article
Cancer Letters, 2015,Volume: 362,Issue: 1,Page: 106-115
Authors:  Shim J.S.;  Li R.-J.;  Lv J.;  Head S.A.;  Yang E.J.;  Liu J.O.
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Angiogenesis  Cholesterol Trafficking  Selective Estrogen Receptor Modulator  Tamoxifen  
Platycodin D triggers autophagy through activation of extracellular signal-regulated kinase in hepatocellular carcinoma HepG2 cells Journal article
European Journal of Pharmacology, 2015,Volume: 749,Page: 81
Authors:  Li T.;  Tang Z.-H.;  Xu W.-S.;  Wu G.-S.;  Wang Y.-F.;  Chang L.-L.;  Zhu H.;  Chen X.-P.;  Wang Y.-T.;  Chen Y.;  Lu J.-J.
Favorite  |  View/Download:2/0  |  Submit date:2018/10/31
Autophagy  Chloroquine  Erk  Hepg2  Platycodin d  Protective  
Low doses of camptothecin induced hormetic and neuroprotective effects in PC12 cells Journal article
Dose-Response, 2015,Volume: 13,Issue: 2
Authors:  Zhang C.;  Chen S.;  Bao J.;  Zhang Y.;  Huang B.;  Jia X.;  Chen M.;  Wan J.-B.;  Su H.;  Wang Y.;  He C.
Favorite  |  View/Download:3/0  |  Submit date:2018/10/31
Hormesis  Neuroprotection  Pc12 Cells  Topoisomerase Inhibitor