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Authentic compound-free strategy for simultaneous determination of primary coumarins in Peucedani Radix using offline high performance liquid chromatography-nuclear magnetic resonance spectroscopy-tandem mass spectrometry Journal article
ACTA PHARMACEUTICA SINICA B, 2018,Volume: 8,Issue: 4,Page: 645-654
Authors:  Liu, Yao;  Song, Qingqing;  Liu, Wenjing;  Li, Peng;  Li, Jun;  Zhao, Yunfang;  Zhang, Liang;  Tu, Pengfei;  Wang, Yitao;  Song, Yuelin
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Authentic Compound-independent Quantitation  Offline Lcnmrms/ms  Automated Fraction Collection Module  Quantitative H-1 Nmr  Peucedani Radix  Regio-specific Monitoring  
Integrated work-flow for quantitative metabolome profiling of plants, Peucedani Radix as a case Journal article
ANALYTICA CHIMICA ACTA, 2017,Volume: 953,Page: 40-47
Authors:  Song, Yuelin;  Song, Qingqing;  Liu, Yao;  Li, Jun;  Wan, Jian-Bo;  Wang, Yitao;  Jiang, Yong;  Tu, Pengfei
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Quantitative Metabolome  Integrated Work-flow  Offline Two Dimensional Liquid  Chromatography  Linear Range  Peucedani Radix  Isomer  
Metabolic characterization of (±)-praeruptorin A in vitro and in vivo by high performance liquid chromatography coupled with hybrid triple quadrupole-linear ion trap mass spectrometry and time-of-flight mass spectrometry Journal article
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2014,Volume: 90,Issue: 5,Page: 98-110
Authors:  Song, Yue-Lin;  Jing, Wang-Hui;  Yan, Ru;  Wang, Yi-Tao
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(+/-)-praeruptorin a  Metabolism  Lightsight (Tm) Software  In Vivo  Peucedani Radix  
H-1 nuclear magnetic resonance based-metabolomic characterization of Peucedani Radix and simultaneous determination of praeruptorin A and praeruptorin B Journal article
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2014,Volume: 93,Issue: SI,Page: 86-94
Authors:  Song, Yue-Lin;  Jing, Wang-Hui;  Chen, Yan-Gan;  Yuan, Yun-Fei;  Yan, Ru;  Wang, Yi-Tao
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Peucedani Radix  Metabolomic Profile  Quantitative H-1 Nmr  Praeruptorin a  Praeruptorin b  
Simultaneously enantiospecific determination of (+)-trans-khellactone, (+/-)-praeruptorin A, (+/-)-praeruptorin B, (+)-praeruptorin E, and their metabolites, (+/-)-cis-khellactone, in rat plasma using Journal article
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2014,Volume: 88,Issue: 1,Page: 269-277
Authors:  Song, Yuelin;  Jing, Wanghui;  Yang, Fengqing;  Shi, Zhan;  Yao, Meicun;  Yan, Ru;  Wang, Yitao
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Online Spe  Chiral Lc-ms/ms  Enantiospecific  Peucedani Radix  Pharmacokinetics  
1H nuclear magnetic resonance based-metabolomic characterization of Peucedani Radix and simultaneous determination of praeruptorin A and praeruptorin B Journal article
Journal of Pharmaceutical and Biomedical Analysis, 2014,Volume: 93,Page: 86-94
Authors:  Song Y.-L.;  Jing W.-H.;  Chen Y.-G.;  Yuan Y.-F.;  Yan R.;  Wang Y.-T.
Favorite  |  View/Download:4/0  |  Submit date:2018/12/28
Metabolomic profile  Peucedani Radix  Praeruptorin A  Praeruptorin B  
Identification of cytochrome P450 isoenzymes involved in metabolism of (+)-praeruptorin A, a calcium channel blocker, by human liver microsomes using ultra high-performance liquid chromatography coupl Journal article
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2013,Volume: 77,Page: 175-188
Authors:  Jing, Wang-Hui;  Song, Yue-Lin;  Yan, Ru;  Wang, Yi-Tao
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Angular-type Pyranocoumarins  (+)-praeruptorin a  Uhplc-qt-ms/ms  Human Liver Microsomes  Cyp 3a4  
Enantioseparation and Absolute Configuration Determination of Angular-Type Pyranocoumarins from Peucedani Radix Using Enzymatic Hydrolysis and Chiral HPLC-MS/MS Analysis Journal article
MOLECULES, 2012,Volume: 17,Issue: 4,Page: 4236-4251
Authors:  Song, YL (Song, Yue-Lin);  Zhang, QW (Zhang, Qing-Wen);  Li, YP (Li, Ya-Ping);  Yan, R (Yan, Ru);  Wang, YT (Wang, Yi-Tao)
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Absolute Configuration  Angular-type Pyranocoumarins  Chiral Lc-ms/ms  Cis-khellactone  Enzymatic Hydrolysis  
Characterization of metabolism of (+)-praeruptorin B and (+)-praeruptorin E in human and rat liver microsomes by liquid chromatography coupled with ion trap mass spectrometry and time-of-flight mass s Journal article
RAPID COMMUNICATIONS IN MASS SPECTROMETRY, 2011,Volume: 25,Issue: 6,Page: 719-730
Authors:  Song, YL (Song, Yue-Lin);  Yan, R (Yan, Ru);  Jing, WH (Jing, Wang-Hui);  Zhao, HY (Zhao, Hai-Yu);  Wang, YT (Wang, Yi-Tao)
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Regulation of human pregnane X receptor and its target gene cytochrome P450 3A4 by Chinese herbal compounds and a molecular docking study Journal article
XENOBIOTICA, 2011,Volume: 41,Issue: 4,Page: 259-280
Authors:  Liu, YH (Liu, Ya-He);  Mo, SL (Mo, Sui-Lin);  Bi, HC (Bi, Hui-Chang);  Hu, BF (Hu, Bing-Fang);  Li, CG (Li, Chun Guang);  Wang, YT (Wang, Yi-Tao);  Huang, L (Huang, Ling);  Huang, M (Huang, Min);  Duan, W (Duan, Wei);  Liu, JP (Liu, Jun-Ping);  Wei, MQ (Wei, Ming Qian);  Zhou, SF (Zhou, Shu-Feng)
Favorite  |  View/Download:11/0  |  Submit date:2018/11/01
Constitutive Androstane Receptor  Primary Human Hepatocytes  Corepressor Silencing-mediator  Hepatoma-cell Lines  Human Cyp3a4 Gene  Nuclear Receptor  Drug-metabolism  Transcriptional Activation  Xenobiotic Receptor  Interindividual Variability