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A new bispecific antibody targeting non-overlapping epitopes on IGF2: Design, in vitro characterization and pharmacokinetics in macaques Journal article
Experimental and Molecular Pathology, 2014,Volume: 97,Issue: 3,Page: 359-367
Authors:  Feng Y.;  Zhao Q.;  Chen W.;  Wang Y.;  Crowder K.;  Dimitrov D.S.
Favorite  |  View/Download:1/0  |  Submit date:2019/01/16
Bispecific Antibodies  Cynomolgus Macaques  Half-life  Igf Ligand  
Metabolic characterization of (+/-)-praeruptorin A in vitro and in vivo by high performance liquid chromatography coupled with hybrid triple quadrupole-linear ion trap mass spectrometry and time-of-fl Journal article
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2014,Volume: 90,Issue: 5,Page: 98-110
Authors:  Song, Yue-Lin;  Jing, Wang-Hui;  Yan, Ru;  Wang, Yi-Tao
View  |  Adobe PDF(3404Kb)  |  Favorite  |  View/Download:55/7  |  Submit date:2018/11/01
(+/-)-praeruptorin a  Metabolism  Lightsight (Tm) Software  In Vivo  Peucedani Radix  
Simultaneously enantiospecific determination of (+)-trans-khellactone, (+/-)-praeruptorin A, (+/-)-praeruptorin B, (+)-praeruptorin E, and their metabolites, (+/-)-cis-khellactone, in rat plasma using Journal article
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2014,Volume: 88,Issue: 1,Page: 269-277
Authors:  Song, Yuelin;  Jing, Wanghui;  Yang, Fengqing;  Shi, Zhan;  Yao, Meicun;  Yan, Ru;  Wang, Yitao
View  |  Adobe PDF(488Kb)  |  Favorite  |  View/Download:101/13  |  Submit date:2018/11/01
Online Spe  Chiral Lc-ms/ms  Enantiospecific  Peucedani Radix  Pharmacokinetics  
Simultaneously enantiospecific determination of (+)-trans-khellactone, (+/-)-praeruptorin A, (+/-)-praeruptorin B, (+)-praeruptorin E, and their metabolites, (+/-)-cis-khellactone, in rat plasma using online solid phase extraction-chiral LC-MS/MS Journal article
Journal of Pharmaceutical and Biomedical Analysis, 2014,Volume: 88,Page: 269
Authors:  Song Y.;  Jing W.;  Yang F.;  Shi Z.;  Yao M.;  Yan R.;  Wang Y.
Favorite  |  View/Download:5/0  |  Submit date:2018/10/31
Chiral LC-MS/MS  Enantiospecific  Online SPE  Peucedani Radix  Pharmacokinetics  
Effects of Nanosuspension Formulations on Transport, Pharmacokinetics, In Vivo Targeting and Efficacy for Poorly Water-soluble Drugs Journal article
Current Pharmaceutical Design, 2014,Volume: 20,Issue: 3,Page: 454 - 473
Authors:  Yancai Wang;  Xiaoqing Miao;  Lin Sun;  Ju Song;  Chao Bi;  Xiao Yang;  Ying Zheng
Favorite  |  View/Download:5/0  |  Submit date:2019/01/29
Nanosuspensions  Absorption  Pharmacokinetics  Drug Targeting  Transport  Efficacy  Toxicity  
Pharmacokinetics of anthraquinones in rat plasma after oral administration of a rhubarb extract Journal article
Biomedical Chromatography, 2014,Volume: 28,Issue: 4,Page: 564
Authors:  Wu W.;  Yan R.;  Yao M.;  Zhan Y.;  Wang Y.
Favorite  |  View/Download:8/0  |  Submit date:2018/10/30
Anthraquinones  Conjugation  Lc-ms/ms  Pharmacokinetics  Rhubarb  
Andrographolide-loaded PLGA-PEG-PLGA micelles to improve its bioavailability and anticancer efficacy Journal article
Expert Opinion on Drug Delivery, 2014,Volume: 11,Issue: 9,Page: 1367
Authors:  Zhang J.;  Li Y.;  Gao W.;  Repka M.A.;  Wang Y.;  Chen M.
Favorite  |  View/Download:1/0  |  Submit date:2018/10/31
Andrographolide  Breast Cancer Mad-mb-231 Cells  Micelles  Pharmacokinetics  Poly (d,L-lactide-co-Glycolide)-b-Poly (Ethylene Glycol)-b-Poly (d,L-lactide-co-Glycolide) Triblock coPolymer  
Regioselective glucuronidation of oxyresveratrol, a natural hydroxystilbene, by human liver and intestinal microsomes and recombinant ugts Journal article
Drug Metabolism and Pharmacokinetics, 2014,Volume: 29,Issue: 3,Page: 229
Authors:  Hu N.;  Mei M.;  Ruan J.;  Wu W.;  Wang Y.;  Yan R.
Favorite  |  View/Download:2/0  |  Submit date:2018/10/31
Glucuronidation  Kinetics  Oxyresveratrol  Oxyresveratrol-2-o-β-d-glucuronosyl  Regioselectivity  Ugt1a9  Uridine Diphospho-glucuronosyltransferase (Ugts)  
Development of enantiospecific and chemoselective methods for the determination of praeruptorin A enantiomers and their metabolites in rat plasma using chiral and achiral LC-MS/MS Journal article
Analytical Methods, 2014,Volume: 6,Issue: 13,Page: 4831
Authors:  Song Y.;  Jing W.;  Tu P.;  Wang Y.
Favorite  |  View/Download:2/0  |  Submit date:2018/10/31