UM

Browse/Search Results:  1-10 of 38 Help

Filters    
Selected(0)Clear Items/Page:    Sort:
Small molecule IVQ, as a prodrug of gluconeogenesis inhibitor QVO, efficiently ameliorates glucose homeostasis in type 2 diabetic mice Journal article
ACTA PHARMACOLOGICA SINICA, 2019,Volume: 40,Issue: 9,Page: 1193-1204
Authors:  Ting-ting Zhou;  Tong Zhao;  Fei Ma;  Yi-nan Zhang;  Jing Jiang;  Yuan Ruan;  Qiu-ying Yan;  Gai-hong Wang;  Jin Ren;  Xiao-wei Guan;  Jun Guo;  Yong-hua Zhao;  Ji-ming Ye;  Li-hong Hu;  Jing Chen;  Xu Shen
Favorite  |  View/Download:5/0  |  Submit date:2020/04/14
Type 2 Diabetes Mellitus  Hepatic Gluconeogenesis  Ampk Signaling Pathway  (e)-3-(2-(Quinoline-4-yl)Vinyl)-1h-indol-6-ol (Qvo)  4-[2-(1h-indol-3-yl)Vinyl]Quinoline (Ivq)  Prodrug  
Rapid identification of antimicrometastases drugs using integrated model systems with two dimensional monolayer, three dimensional spheroids, and zebrafish xenotransplantation tumors Journal article
BIOTECHNOLOGY AND BIOENGINEERING, 2018,Volume: 115,Issue: 11,Page: 2828-2843
Authors:  Fu, Afu;  Peh, Yu Ming;  Ngan, Weida;  Wei, Na;  Luo, Kathy Qian
Favorite  |  View/Download:7/0  |  Submit date:2019/01/17
antimetastasis drug discovery  fluorescence resonance energy transfer  PI3K  AKT pathway  three dimensional tumor spheroids  zebrafish xenograft tumor model  
Dual-functional Brij-S20-modified nanocrystal formulation enhances the intestinal transport and oral bioavailability of berberine Journal article
INTERNATIONAL JOURNAL OF NANOMEDICINE, 2018,Volume: 13,Page: 3781-3793
Authors:  Xiong, Wei;  Sang, Wei;  Linghu, Ke Gang;  Zhong, Zhang Feng;  Cheang, Wai San;  Li, Juan;  Hu, Yuan Jia;  Yu, Hua;  Wang, Yi Tao
Favorite  |  View/Download:131/0  |  Submit date:2018/10/30
Berberine  Poor Water Solubility  Pgp-mediated Drug Efflux  Brij  Nanocrystals  
Cleavable Multifunctional Targeting Mixed Micelles with Sequential pH-Triggered TAT Peptide Activation for Improved Antihepatocellular Carcinoma Efficacy Journal article
MOLECULAR PHARMACEUTICS, 2017,Volume: 14,Issue: 11,Page: 3644-3659
Authors:  Zhang, Jinming;  Zheng, Yifeng;  Xie, Xi;  Wang, Lan;  Su, Ziren;  Wang, Yitao;  Leong, Kam W.;  Chen, Meiwan
View  |  Adobe PDF(2484Kb)  |  Favorite  |  View/Download:645/48  |  Submit date:2018/10/30
Tumor-targeting  Glycyrrhetinic Acid  Ph-sensitive  Tat Exposure  Mixed Micelles  
Pharmacokinetic Comparison of Seven Major Bio-Active Components in Normal and Blood Stasis Rats after Oral Administration of Herb Pair Danggui-Honghua by UPLC-TQ/MS Journal article
MOLECULES, 2017,Volume: 22,Issue: 10
Authors:  Jin, Yi;  Tang, Yu-Ping;  Zhu, Zhen-Hua;  Shang, Er-Xin;  Pang, Han-Qing;  Shi, Xu-Qin;  Chen, Yan-Yan;  Wang, Jin;  Chang, Xing;  Kang, An;  Zhou, Gui-Sheng;  Shi, Ya-Jun;  Sun, Jin;  Tang, Zhi-Shu;  Li, Shao-Ping;  Duan, Jin-Ao
Favorite  |  View/Download:20/0  |  Submit date:2018/10/30
Danggui  Angelica sinensis  honghua  Carthamus tinctorius  herb pair  pharmacokinetics  
Simultaneous quantification six active compounds in rat plasma by UPLC-MS/MS and its application to a pharmacokinetic study of Pien-Tze-Huang Journal article
JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 2017,Volume: 1061,Page: 314-321
Authors:  Xu, Wen;  Zhang, Yiping;  Zhou, Caijie;  Tai, Yanni;  Zhang, Xiaoqing;  Liu, Jie;  Sha, Mei;  Huang, Mingqing;  Zhu, Yanlin;  Peng, Jun;  Lu, Jin-Jian
Favorite  |  View/Download:11/0  |  Submit date:2018/10/30
Pian-tze-huang  Uplc-ms/ms  Ginsenosides  Muscone  Pharmacokinetics  
Schisandrin B reverses doxorubicin resistance through inhibiting P-glycoprotein and promoting proteasome-mediated degradation of survivin Journal article
SCIENTIFIC REPORTS, 2017,Volume: 7
Authors:  Wang, Shengpeng;  Wang, Anqi;  Shao, Min;  Lin, Ligen;  Li, Peng;  Wang, Yitao
View  |  Adobe PDF(3646Kb)  |  Favorite  |  View/Download:279/4  |  Submit date:2018/10/30
Angiotensin II induces connective tissue growth factor expression in human hepatic stellate cells by a transforming growth factor beta-independent mechanism Journal article
SCIENTIFIC REPORTS, 2017,Volume: 7
Authors:  Li, Ao;  Zhang, Jingyao;  Zhang, Xiaoxun;  Wang, Jun;  Wang, Songsong;  Xiao, Xiao;  Wang, Rui;  Li, Peng;  Wang, Yitao
View  |  Adobe PDF(3646Kb)  |  Favorite  |  View/Download:299/6  |  Submit date:2018/10/30
Big data analysis of global advances in pharmaceutics and drug delivery 1980-2014 Journal article
DRUG DISCOVERY TODAY, 2017,Volume: 22,Issue: 8,Page: 1201-1208
Authors:  Zhang, Weixiang;  Zhao, Qianqian;  Deng, Junling;  Hu, Yuanjia;  Wang, Yitao;  Ouyang, Defang
View  |  Adobe PDF(3646Kb)  |  Favorite  |  View/Download:335/11  |  Submit date:2018/10/30
Co-delivery of paclitaxel and tetrandrine via iRGD peptide conjugated lipid-polymer hybrid nanoparticles overcome multidrug resistance in cancer cells Journal article
SCIENTIFIC REPORTS, 2017,Volume: 7
Authors:  Zhang, Jinming;  Wang, Lu;  Chan, Hon Fai;  Xie, Wei;  Chen, Sheng;  He, Chengwei;  Wang, Yitao;  Chen, Meiwan
View  |  Adobe PDF(1919Kb)  |  Favorite  |  View/Download:307/10  |  Submit date:2018/10/30