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Metformin protects PC12 cells and hippocampal neurons from H2O (2)-induced oxidative damage through activation of AMPK pathway Journal article
JOURNAL OF CELLULAR PHYSIOLOGY, 2019,Volume: 234,Issue: 9,Page: 16619-16629
Authors:  Xia Zhao;  Zhiwen Zeng;  Uma Gaur;  Jiankang Fang;  Tangming Peng;  Shuai Li;  Wenhua Zheng
Favorite  |  View/Download:8/0  |  Submit date:2020/06/11
Aging  Amp-activated Protein Kinase  Hydrogen Peroxide  Metformin  Pc12 Cells  
Mitochondrial protective effect of neferine through the modulation of nuclear factor erythroid 2-related factor 2 signalling in ischaemic stroke Journal article
BRITISH JOURNAL OF PHARMACOLOGY, 2019,Volume: 176,Issue: 3,Page: 400-415
Authors:  Chuanhong Wu;  Jianxin Chen;  Ruocong Yang;  Feipeng Duan;  Shaojing Li;  Xiuping Chen
Favorite  |  View/Download:13/0  |  Submit date:2020/01/07
Novel neurotoxic peptides from Protopalythoa variabilis virtually interact with voltage-gated sodium channel and display anti-epilepsy and neuroprotective activities in zebrafish Journal article
Archives of Toxicology, 2019,Volume: 93,Issue: 1,Page: 189-206
Authors:  Liao Q.;  Li S.;  Siu S.W.I.;  Morlighem J.-E.R.L.;  Wong C.T.T.;  Wang X.;  Radis-Baptista G.;  Lee S.M.-Y.
Favorite  |  View/Download:17/0  |  Submit date:2019/04/04
Anti-epilepsy  Disulfide Bond  Neuroactive Peptides  Neuroprotection  Protein Docking  Voltage-gated Sodium Ion Channel Blocker  
N-Propargyl Caffeamide (PACA) Ameliorates Dopaminergic Neuronal Loss and Motor Dysfunctions in MPTP Mouse Model of Parkinson's Disease and in MPP+-Induced Neurons via Promoting the Conversion of proNGF to NGF Journal article
MOLECULAR NEUROBIOLOGY, 2018,Volume: 55,Issue: 3,Page: 2258-2267
Authors:  Luo, Dan;  Zhao, Jia;  Cheng, Yuanyuan;  Lee, Simon Ming-Yuen;  Rong, Jianhui
Favorite  |  View/Download:10/0  |  Submit date:2018/10/31
Parkinson's disease  Neuroprotection  N-propargyl caffeamide (PACA)  NGF/TrkApathway  PI3K/Akt  ERK1/2  
N-Propargyl Caffeamide (PACA) Ameliorates Dopaminergic Neuronal Loss and Motor Dysfunctions in MPTP Mouse Model of Parkinson's Disease and in MPP+-Induced Neurons via Promoting the Conversion of proNGF to NGF Journal article
MOLECULAR NEUROBIOLOGY, 2018,Volume: 55,Issue: 3,Page: 2258-2267
Authors:  Luo, Dan;  Zhao, Jia;  Cheng, Yuanyuan;  Lee, Simon Ming-Yuen;  Rong, Jianhui
Favorite  |  View/Download:16/0  |  Submit date:2018/10/31
Parkinson's disease  Neuroprotection  N-propargyl caffeamide (PACA)  NGF/TrkApathway  PI3K/Akt  ERK1/2  
N-Propargyl Caffeamide (PACA) Ameliorates Dopaminergic Neuronal Loss and Motor Dysfunctions in MPTP Mouse Model of Parkinson's Disease and in MPP+-Induced Neurons via Promoting the Conversion of proNGF to NGF Journal article
MOLECULAR NEUROBIOLOGY, 2018,Volume: 55,Issue: 3,Page: 2258-2267
Authors:  Luo, Dan;  Zhao, Jia;  Cheng, Yuanyuan;  Lee, Simon Ming-Yuen;  Rong, Jianhui
Favorite  |  View/Download:10/0  |  Submit date:2018/10/30
Parkinson's disease  Neuroprotection  N-propargyl caffeamide (PACA)  NGF/TrkApathway  PI3K/Akt  ERK1/2  
Substantial protection against MPTP-associated Parkinson's neurotoxicity in vitro and in vivo by anti-cancer agent SU4312 via activation of MEF2D and inhibition of MAO-B Journal article
NEUROPHARMACOLOGY, 2017,Volume: 126,Page: 12-24
Authors:  Guo, Baojian;  Hu, Shengquan;  Zheng, Chengyou;  Wang, Hongyu;  Luo, Fangcheng;  Li, Haitao;  Cui, Wei;  Yang, Xifei;  Cui, Guozhen;  Mak, Shinghung;  Choi, Tony Chung-Lit;  Ma, Edmond Dik-Lung;  Wang, Yuqiang;  Lee, Simon Ming Yuen;  Zhang, Zaijun;  Han, Yifan
View  |  Adobe PDF(2766Kb)  |  Favorite  |  View/Download:432/9  |  Submit date:2018/10/31
Parkinson's disease  SU4312  Neuroprotection  Myocyte enhancer factor 2D  Monoamine oxidase-B  
Substantial protection against MPTP-associated Parkinson's neurotoxicity in vitro and in vivo by anti-cancer agent SU4312 via activation of MEF2D and inhibition of MAO-B Journal article
NEUROPHARMACOLOGY, 2017,Volume: 126,Page: 12-24
Authors:  Guo, Baojian;  Hu, Shengquan;  Zheng, Chengyou;  Wang, Hongyu;  Luo, Fangcheng;  Li, Haitao;  Cui, Wei;  Yang, Xifei;  Cui, Guozhen;  Mak, Shinghung;  Choi, Tony Chung-Lit;  Ma, Edmond Dik-Lung;  Wang, Yuqiang;  Lee, Simon Ming Yuen;  Zhang, Zaijun;  Han, Yifan
Favorite  |  View/Download:22/0  |  Submit date:2018/10/30
Parkinson's disease  SU4312  Neuroprotection  Myocyte enhancer factor 2D  Monoamine oxidase-B  
C-21 steroidal glycosides from Cynanchum auriculatum and their neuroprotective effects against H2O2-induced damage in PC12 cells Journal article
PHYTOCHEMISTRY, 2017,Volume: 140,Page: 1-15
Authors:  Qian, Xicheng;  Li, Baocai;  Li, Peng;  Wang, Dong;  Dai, Weifeng;  Zhang, Mi
Favorite  |  View/Download:15/0  |  Submit date:2018/10/30
Cynanchum auriculatum  Apocynaceae  C-21 steroidal glycosides  Neuroprotecton  PC12  Apoptosis  
The Atypical Antipsychotic Agent, Clozapine, Protects Against Corticosterone-Induced Death of PC12 Cells by Regulating the Akt/FoxO3a Signaling Pathway Journal article
MOLECULAR NEUROBIOLOGY, 2017,Volume: 54,Issue: 5,Page: 3395-3406
Authors:  Zeng, Zhiwen;  Wang, Xue;  Bhardwaj, Sanjeev K.;  Zhou, Xuanhe;  Little, Peter J.;  Quirion, Remi;  Srivastava, Lalit K.;  Zheng, Wenhua
Favorite  |  View/Download:18/0  |  Submit date:2018/10/30
Schizophrenia  Clozapine  Corticosterone  Pi3k/akt/foxo3a  Neuroprotection