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Tanshinone IIA attenuates insulin like growth factor 1-induced cell proliferation in PC12 cells through the PI3K/Akt and MEK/ERK pathways Journal article
International Journal of Molecular Sciences, 2018,Volume: 19,Issue: 9
Authors:  Wang H.;  Su X.;  Fang J.;  Xin X.;  Zhao X.;  Gaur U.;  Wen Q.;  Xu J.;  Little P.J.;  Zheng W.
Favorite  |  View/Download:17/0  |  Submit date:2018/12/21
Akt  Antiproliferation  ERK  IGF-1R  Tanshinone IIA  
N-Propargyl Caffeamide (PACA) Ameliorates Dopaminergic Neuronal Loss and Motor Dysfunctions in MPTP Mouse Model of Parkinson’s Disease and in MPP+-Induced Neurons via Promoting the Conversion of proNGF to NGF Journal article
Molecular Neurobiology, 2018,Volume: 55,Issue: 3,Page: 2258-2267
Authors:  Luo D.;  Zhao J.;  Cheng Y.;  Lee S.M.-Y.;  Rong J.
Favorite  |  View/Download:4/0  |  Submit date:2018/11/06
ERK1/2  N-propargyl caffeamide (PACA)  Neuroprotection  NGF/TrkA pathway  Parkinson’s disease  PI3K/Akt  
Substantial protection against MPTP-associated Parkinson's neurotoxicity in vitro and in vivo by anti-cancer agent SU4312 via activation of MEF2D and inhibition of MAO-B Journal article
Neuropharmacology, 2017,Volume: 126,Page: 12-24
Authors:  Guo B.;  Hu S.;  Zheng C.;  Wang H.;  Luo F.;  Li H.;  Cui W.;  Yang X.;  Cui G.;  Mak S.;  Choi T.C.-L.;  Ma E.D.-L.;  Wang Y.;  Lee S.M.Y.;  Zhang Z.;  Han Y.
Favorite  |  View/Download:13/0  |  Submit date:2018/11/06
Monoamine oxidase-B  Myocyte enhancer factor 2D  Neuroprotection  Parkinson's disease  SU4312  
Substantial protection against MPTP-associated Parkinson's neurotoxicity in vitro and in vivo by anti-cancer agent SU4312 via activation of MEF2D and inhibition of MAO-B Journal article
Neuropharmacology, 2017,Volume: 126,Page: 12-24
Authors:  Guo B.;  Hu S.;  Zheng C.;  Wang H.;  Luo F.;  Li H.;  Cui W.;  Yang X.;  Cui G.;  Mak S.;  Choi T.C.-L.;  Ma E.D.-L.;  Wang Y.;  Lee S.M.Y.;  Zhang Z.;  Han Y.
Favorite  |  View/Download:9/0  |  Submit date:2018/11/06
Monoamine oxidase-B  Myocyte enhancer factor 2D  Neuroprotection  Parkinson's disease  SU4312  
C21 steroidal glycosides from Cynanchum auriculatum and their neuroprotective effects against H2O2-induced damage in PC12 cells Journal article
Phytochemistry, 2017,Volume: 140,Page: 1-15
Authors:  Qian X.;  Li B.;  Li P.;  Wang D.;  Dai W.;  Zhang M.
Favorite  |  View/Download:3/0  |  Submit date:2018/12/28
Apocynaceae  Apoptosis  C21 steroidal glycosides  Cynanchum auriculatum  Neuroprotecton  PC12  
Role of brain-derived neurotrophic factor and nerve growth factor in the regulation of Neuropeptide W in vitro and in vivo Journal article
Molecular and Cellular Endocrinology, 2017,Volume: 447,Page: 71-78
Authors:  Wang R.;  Yan F.;  Liao R.;  Wan P.;  Little P.J.;  Zheng W.
Favorite  |  View/Download:2/0  |  Submit date:2018/12/21
HPA axis  Neuropeptide W  Neurotrophins  PI3K/Akt  
Potent Protection Against MPP+-Induced Neurotoxicity via Activating Transcription Factor MEF2D by a Novel Derivative of Naturally Occurring Danshensu/Tetramethylpyrazine Journal article
NeuroMolecular Medicine, 2016,Volume: 18,Issue: 4,Page: 561-572
Authors:  Hu S.;  Wang L.;  Mak S.;  Zhang Z.;  Xu D.;  Li H.;  Li Y.;  Hu Y.;  Lee S.M.Y.;  Wang Y.;  Han Y.
Favorite  |  View/Download:4/0  |  Submit date:2018/11/06
Danshensu/tetramethylpyrazine derivative  GSK3β  MEF2D  MPP+  Neuroprotection  Parkinson’s disease  
Neuroprotection against glutamate-induced excitotoxicity and induction of neurite outgrowth by T-006, a novel multifunctional derivative of tetramethylpyrazine in neuronal cell models Journal article
Neurochemistry International, 2016,Volume: 99,Page: 194-205
Authors:  Xu D.;  Chen H.;  Mak S.;  Hu S.;  Tsim K.W.K.;  Hu Y.;  Sun Y.;  Zhang G.;  Wang Y.;  Zhang Z.;  Han Y.
Favorite  |  View/Download:2/0  |  Submit date:2018/12/28
Alzheimer's disease  Excitotoxicity  Neurite outgrowth  Neuroprotection  Tetramethylpyrazine derivative  
A novel Nogo-66 receptor antagonist peptide promotes neurite regeneration in vitro Journal article
Molecular and Cellular Neuroscience, 2016,Volume: 71,Page: 80-91
Authors:  Sun Z.;  Dai X.;  Li Y.;  Jiang S.;  Lou G.;  Cao Q.;  Hu R.;  Huang Y.;  Su Z.;  Chen M.;  Luo H.;  Lin X.;  Sun J.;  Xiao F.
Favorite  |  View/Download:4/0  |  Submit date:2018/12/27
Antagonist peptide  Neurite regeneration  Nogo-66 receptor  Phage display  
Chemically bonding of amantadine with gardenamide A enhances the neuroprotective effects against corticosterone-induced insults in PC12 cells Journal article
International Journal of Molecular Sciences, 2015,Volume: 16,Issue: 9,Page: 22795-22810
Authors:  Zhao J.;  Peng L.;  Zheng W.;  Wang R.;  Zhang L.;  Yang J.;  Chen H.
Favorite  |  View/Download:4/0  |  Submit date:2018/12/21
Amantadine  eNOS  Gardenamide A  Neuroprotection  NMDA  nNOS