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Postnatal deletion of Alk5 gene in meniscal cartilage accelerates age-dependent meniscal degeneration in mice Journal article
Journal of Cellular Physiology, 2019,Volume: 234,Issue: 1,Page: 595-605
Authors:  Wang Q.;  Tan Q.;  Xu W.;  Kuang L.;  Zhang B.;  Wang Z.;  Ni Z.;  Su N.;  Jin M.;  Li C.;  Jiang W.;  Huang J.;  Li F.;  Zhu Y.;  Chen H.;  Du X.;  Chen D.;  Deng C.;  Qi H.;  Xie Y.;  Chen L.
Favorite  |  View/Download:18/0  |  Submit date:2018/12/13
Activing Receptor-like Kinases 5 (Alk5)  Matrix Degradation  Meniscal Degeneration  Transforming Growth Factor-β (Tgf-β) Signaling  
Adeno-Associated Virus-Mediated RNAi against Mutant Alleles Attenuates Abnormal Calvarial Phenotypes in an Apert Syndrome Mouse Model Journal article
Molecular Therapy - Nucleic Acids, 2018,Volume: 13,Page: 291-302
Authors:  Luo F.;  Xie Y.;  Wang Z.;  Huang J.;  Tan Q.;  Sun X.;  Li F.;  Li C.;  Liu M.;  Zhang D.;  Xu M.;  Su N.;  Ni Z.;  Jiang W.;  Chang J.;  Chen H.;  Chen S.;  Xu X.;  Deng C.;  Wang Z.;  Du X.;  Chen L.
Favorite  |  View/Download:14/0  |  Submit date:2018/12/13
Adeno-associated Virus  Apert Syndrome  Craniosynostosis  Fgfr2  Molecular Therapy  Rnai  
A novel FGFR1-binding peptide attenuates the degeneration ofarticular cartilage in adult mice Journal article
Osteoarthritis and Cartilage, 2018,Volume: 26,Issue: 12,Page: 1733-1743
Authors:  Q. Tan;  B. Chen;  Q. Wang;  W.Xu;  Y.Wang;  Z. Lin;  F.Luo;  S. Huang;  Y.Zhu;  N. Su;  M. Jin;  C.Li;  L. Kuang;  H.Qi;  Z.Ni;  Z. Wang;  X. Luo;  W. Jiang;  H. Chen;  S. Chen;  F.Li;  B. Zhang;  J. Huang;  R. Zhang;  K. Jin;  X.Xu;  C. Deng;  X.Du;  Y. Xie;  L. Chen
Favorite  |  View/Download:16/0  |  Submit date:2018/12/17
Fgfr1  Peptide  Osteoarthritis  Mice  
Andrographolide derivative as STAT3 inhibitor that protects acute liver damage in mice Journal article
BIOORGANIC & MEDICINAL CHEMISTRY, 2018,Volume: 26,Issue: 18,Page: 5053-5061
Authors:  Chen, Shao-Ru;  Li, Feng;  Ding, Mo-Yu;  Wang, Decai;  Zhao, Qi;  Wang, Yitao;  Zhou, Guo-Chun;  Wang, Ying
View  |  Adobe PDF(2009Kb)  |  Favorite  |  View/Download:285/38  |  Submit date:2018/10/30
Andrographolide  Stat3 Inhibitor  Acute Liver Damage  Inflammation  
Vascular ADAM17 (a Disintegrin and Metalloproteinase Domain 17) Is Required for Angiotensin II/β-Aminopropionitrile-Induced Abdominal Aortic Aneurysm Journal article
Hypertension, 2017,Volume: 70,Issue: 5,Page: 959-963
Authors:  Kawai T.;  Takayanagi T.;  Forrester S.J.;  Preston K.J.;  Obama T.;  Tsuji T.;  Kobayashi T.;  Boyer M.J.;  Cooper H.A.;  Kwok H.F.;  Hashimoto T.;  Scalia R.;  Rizzo V.;  Eguchi S.
Favorite  |  View/Download:2/0  |  Submit date:2018/12/19
Aneurysm  Angiotensin Ii  Hypertension  Rupture  Signal Transduction  
Intravital imaging of osteocytes in mouse calvaria using third harmonic generation microscopy Journal article
PLOS ONE, 2017,Volume: 12,Issue: 10
Authors:  Tokarz, Danielle;  Cisek, Richard;  Wein, Marc N.;  Turcotte, Raphael;  Haase, Christa;  Yeh, Shu-Chi A.;  Bharadwaj, Srinidhi;  Raphael, Anthony P.;  Paudel, Hari;  Alt, Clemens;  Liu, Tzu-Ming;  Kronenberg, Henry M.;  Lin, Charles P.
Favorite  |  View/Download:13/0  |  Submit date:2018/10/30
Modulating the phenotype of host macrophages to enhance osteogenesis in MSC-laden hydrogels: Design of a glucomannan coating material Journal article
BIOMATERIALS, 2017,Volume: 139,Page: 39-55
Authors:  Niu, Yiming;  Li, Qiu;  Xie, Ruiyu;  Liu, Shang;  Wang, Ruibing;  Xing, Panfei;  Shi, Yuchen;  Wang, Yitao;  Dong, Lei;  Wang, Chunming
View  |  Adobe PDF(5330Kb)  |  Favorite  |  View/Download:94/4  |  Submit date:2018/10/30
Bioactive Coating  Glucomannan Polysaccharides  Scaffold-tissue Integration  Macrophages  Osteogenesis  
Development of a specific affinity-matured exosite inhibitor to MT1-MMP that efficiently inhibits tumor cell invasion in vitro and metastasis in vivo Journal article
Oncotarget, 2016,Volume: 7,Issue: 13,Page: 16773-16792
Authors:  Botkjaer K.A.;  Kwok H.F.;  Terp M.G.;  Karatt-Vellatt A.;  Santamaria S.;  McCafferty J.;  Andreasen P.A.;  Itoh Y.;  Ditzel H.J.;  Murphy G.
Favorite  |  View/Download:5/0  |  Submit date:2018/12/19
Antibody  In Vivo targetIng  Metastasis  Mt1-mmp  Non-catalytic Sites  
Integrating the GPCR transactivation-dependent and biased signalling paradigms in the context of PAR1 signalling Journal article
British Journal of Pharmacology, 2016,Volume: 173,Issue: 20,Page: 2992-3000
Authors:  Little P.J.;  Hollenberg M.D.;  Kamato D.;  Thomas W.;  Chen J.;  Wang T.;  Zheng W.;  Osman N.
Favorite  |  View/Download:10/0  |  Submit date:2018/12/21
Pharmacokinetics screening for multi-components absorbed in the rat plasma after oral administration of traditional Chinese medicine Flos Lonicerae Japonicae-Fructus Forsythiae herb couple by sequential negative and positive ionization ultra-high-performance liquid chromatography/tandem triple quadrupole mass spectrometric detection Journal article
Journal of Chromatography A, 2015,Volume: 1376,Page: 84-97
Authors:  Zhou W.;  Tam K.Y.;  Meng M.;  Shan J.;  Wang S.;  Ju W.;  Cai B.;  Di L.
Favorite  |  View/Download:2/0  |  Submit date:2018/12/18
Dilution Technology  Flos Lonicerae Japonicae-fructus Forsythiae Herb Couple  Liquid-liquid Extraction  Matrix Effect  Multi-compounds  Pharmacokinetics