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A dual-specific IGF-I/II human engineered antibody domain inhibits IGF signaling in breast cancer cells Journal article
International Journal of Biological Sciences, 2018,Volume: 14,Issue: 7,Page: 799–806
作者:  Zhizhen Chen;  Jie Liu;  Dafeng Chu;  Yaming Shan;  Guixing Ma;  Hongmin Zhang;  Xiaohua Douglas Zhang;  Pu Wang;  Qiang Chen;  Chuxia Deng;  Weizao Chen;  Dimiter Dimitrov;  Qi Zhao
收藏  |  浏览/下载:7/0  |  提交时间:2018/12/17
Insulin-like Growth Factor  Yeast Display  Affinity Maturation  Ead  
Discovery and preliminary SAR of 14-aryloxy-andrographolide derivatives as antibacterial agents with immunosuppressant activity Journal article
RSC ADVANCES, 2018,Volume: 8,Issue: 17,Page: 9440-9456
作者:  Li, Feng;  Li, Xiao-Min;  Sheng, Dekuan;  Chen, Shao-Ru;  Nie, Xin;  Liu, Zhuyun;  Wang, Decai;  Zhao, Qi;  Wang, Yitao;  Wang, Ying;  Zhou, Guo-Chun
浏览  |  Adobe PDF(583Kb)  |  收藏  |  浏览/下载:158/10  |  提交时间:2018/10/30
A new bispecific antibody targeting non-overlapping epitopes on IGF2: Design, in vitro characterization and pharmacokinetics in macaques Journal article
Experimental and Molecular Pathology, 2014,Volume: 97,Issue: 3,Page: 359-367
作者:  Feng Y.;  Zhao Q.;  Chen W.;  Wang Y.;  Crowder K.;  Dimitrov D.S.
收藏  |  浏览/下载:4/0  |  提交时间:2019/01/16
Bispecific Antibodies  Cynomolgus Macaques  Half-life  Igf Ligand  
Human monoclonal antibodies to IGF1/2 with picomolar affinity Journal article
MOLECULAR CANCER THERAPEUTICS, 2011,Volume: 10,Issue: 9,Page: 1677-1685
作者:  Qi Zhao;  Yang Feng;  Zhongyu Zhu;  Dimiter S. Dimitrov
收藏  |  浏览/下载:1/0  |  提交时间:2019/01/23
Mab  Igf2  Picomolar Affinity  Phage Display  Yeast Display  Igf1