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Toosendanin, a natural product, inhibited TGF-1-induced epithelial-mesenchymal transition through ERK/Snail pathway Journal article
PHYTOTHERAPY RESEARCH, 2018,Volume: 32,Issue: 10,Page: 2009-2020
Authors:  Luo, Weiwei;  Liu, Xin;  Sun, Wen;  Lu, Jin-Jian;  Wang, Yitao;  Chen, Xiuping
View  |  Adobe PDF(2621Kb)  |  Favorite  |  View/Download:244/23  |  Submit date:2018/10/30
Emt  Erk1/2  Snail  Lung Cancer  Toosendanin  
2-methoxy-6-acetyl-7-methyljuglone (MAM) induces iNOS/NO-mediated DNA damage response through activation of MAPKs pathways Journal article
Anti-Cancer Agents in Medicinal Chemistry, 2018,Volume: 18,Issue: 6,Page: 903-913
Authors:  Niu Y.;  Yuan R.;  Gao H.;  Lu J.-J.;  Kong Q.;  Chen X.
Favorite  |  View/Download:6/0  |  Submit date:2018/12/28
Atm/chk2  Dna Damage  Inos/no  L-arginine  Mam  Mapks  
Osimertinib (AZD9291) decreases programmed death ligand-1 in EGFR-mutated non-small cell lung cancer cells Journal article
ACTA PHARMACOLOGICA SINICA, 2017,Volume: 38,Issue: 11,Page: 1512-1520
Authors:  Jiang, Xiao-Ming;  Xu, Yu-Lian;  Huang, Mu-Yang;  Zhang, Le-Le;  Su, Min-Xia;  Chen, Xiuping;  Lu, Jin-Jian
Favorite  |  View/Download:15/0  |  Submit date:2018/10/30
Non-small Cell Lung Cancer  Egfr  Osimertinib  Pd-l1  Ubiquitin-proteasome System  Mg-132  Bortezomib  Gsk3 Beta  Licl  
Natural autophagy blockers, dauricine (DAC) and daurisoline (DAS), sensitize cancer cells to camptothecin-induced toxicity Journal article
ONCOTARGET, 2017,Volume: 8,Issue: 44,Page: 77673-77684
Authors:  Wu, Ming-Yue;  Wang, Sheng-Fang;  Cai, Cui-Zan;  Tan, Jie-Qiong;  Li, Min;  Lu, Jin-Jian;  Chen, Xiu-Ping;  Wang, Yi-Tao;  Zheng, Wei;  Lu, Jia-Hong
Favorite  |  View/Download:14/0  |  Submit date:2018/10/30
Dauricine  Daurisoline  Autophagy Blocker  Cancer Cells  Cell Toxicity  
Garcinone E induces apoptosis and inhibits migration and invasion in ovarian cancer cells Journal article
SCIENTIFIC REPORTS, 2017,Volume: 7
Authors:  Xu, Xiao-Huang;  Liu, Qian-Yu;  Li, Ting;  Liu, Jian-Lin;  Chen, Xin;  Huang, Li;  Qiang, Wen-An;  Chen, Xiuping;  Wang, Yitao;  Lin, Li-Gen;  Lu, Jin-Jian
View  |  Adobe PDF(5330Kb)  |  Favorite  |  View/Download:128/10  |  Submit date:2018/10/30
Novel Hsp90 inhibitor platycodin D disrupts Hsp90/Cdc37 complex and enhances the anticancer effect of mTOR inhibitor Journal article
TOXICOLOGY AND APPLIED PHARMACOLOGY, 2017,Volume: 330,Page: 65-73
Authors:  Li, Ting;  Chen, Xin;  Dai, Xiao-Yang;  Wei, Bin;  Weng, Qin-Jie;  Chen, Xiuping;  Ouyang, De-Fang;  Yan, Ru;  Huang, Zhang-Jian;  Jiang, Hu-Lin;  Zhu, Hong;  Lu, Jin-Jian
Favorite  |  View/Download:7/0  |  Submit date:2018/10/30
Everolimus  Platycodin d  Hsp90  Cdc37  Egfr  Igf1r  
Tert-butyl hydroperoxide (t-BHP) induced apoptosis and necroptosis in endothelial cells: Roles of NOX4 and mitochondrion Journal article
REDOX BIOLOGY, 2017,Volume: 11,Page: 524-534
Authors:  Zhao, Wenwen;  Feng, Haitao;  Sun, Wen;  Liu, Kang;  Lu, Jin-Jian;  Chen, Xiuping
Favorite  |  View/Download:9/0  |  Submit date:2018/10/30
Apoptosis  Necroptosis  Reactive Oxygen Species  Nox4  Mitochondria  Endothelial Cells  
Platycodin D potentiates proliferation inhibition and apoptosis induction upon AKT inhibition via feedback blockade in non-small cell lung cancer cells Journal article
Scientific Reports, 2016,Volume: 6
Authors:  Li T.;  Chen X.;  Chen X.;  Ma D.L.;  Leung C.H.;  Lu J.J.
Favorite  |  View/Download:6/0  |  Submit date:2018/11/06
Cucurbitacin e induces caspase-dependent apoptosis and protective autophagy mediated by ROS in lung cancer cells Journal article
Chemico-Biological Interactions, 2016,Volume: 253,Page: 1
Authors:  Ma G.;  Luo W.;  Lu J.;  Ma D.-L.;  Leung C.-H.;  Wang Y.;  Chen X.
Favorite  |  View/Download:2/0  |  Submit date:2018/10/31
Apoptosis  Autophagy  Cancer  Cucurbitacin e  Reactive Oxygen Species  
Total tanshinones-induced apoptosis and autophagy via reactive oxygen species in lung cancer 95D Cells Journal article
American Journal of Chinese Medicine, 2015,Volume: 43,Issue: 6,Page: 1265-1279
Authors:  Gao H.;  Sun W.;  Zhao W.;  Hao W.;  Leung C.-H.;  Lu J.;  Chen X.
Favorite  |  View/Download:2/0  |  Submit date:2018/11/06
Apoptosis  Autophagy  Reactive Oxygen Species  Total Tanshinones