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Tricyclic thiazoles are a new class of angiogenesis inhibitors Journal article
Bioorganic and Medicinal Chemistry Letters, 2013,Volume: 23,Issue: 9,Page: 2733-2737
Authors:  Bhat S.;  Shim J.S.;  Liu J.O.
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Angiogenesis  Endothelial cells  Tricyclic thiazoles  
Substituted 3-(4-(1,3,5-triazin-2-yl)-phenyl)-2-aminopropanoic acids as novel tryptophan hydroxylase inhibitors Journal article
Bioorganic and Medicinal Chemistry Letters, 2009,Volume: 19,Issue: 17,Page: 5229-5232
Authors:  Jin H.;  Cianchetta G.;  Devasagayaraj A.;  Gu K.;  Marinelli B.;  Samala L.;  Scott S.;  Stouch T.;  Tunoori A.;  Wang Y.;  Zang Y.;  Zhang C.;  David Kimball S.;  Main A.J.;  Ding Z.-M.;  Sun W.;  Yang Q.;  Yu X.-Q.;  Powell D.R.;  Wilson A.;  Liu Q.;  Shi Z.-C.
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5-HT  Gastrointestinal disorders  TPH1  Tryptophan hydroxylase  
The discovery of AZD5597, a potent imidazole pyrimidine amide CDK inhibitor suitable for intravenous dosing Journal article
Bioorganic and Medicinal Chemistry Letters, 2008,Volume: 18,Issue: 24,Page: 6369-6373
Authors:  Jones C.D.;  Andrews D.M.;  Barker A.J.;  Blades K.;  Daunt P.;  East S.;  Geh C.;  Graham M.A.;  Johnson K.M.;  Loddick S.A.;  McFarland H.M.;  McGregor A.;  Moss L.;  Rudge D.A.;  Simpson P.B.;  Swain M.L.;  Tam K.Y.;  Tucker J.A.;  Walker M.
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Anti-cancer  Cdk  Cell Cycle  Cyclin-dependent Kinase  Imidazole Amide  Kinase  Kinase Inhibitor  
Synthesis and evaluation of heteroaryl-ketone derivatives as a novel class of VEGFR-2 inhibitors Journal article
Bioorganic and Medicinal Chemistry Letters, 2008,Volume: 18,Issue: 15,Page: 4344-4347
Authors:  Piatnitski Chekler E.L.;  Katoch-Rouse R.;  Kiselyov A.S.;  Sherman D.;  Ouyang X.;  Kim K.;  Wang Y.;  Hadari Y.R.;  Doody J.F.
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Angiogenesis  Kinase inhibitor  Vascular endothelial growth factor  
Novel tricyclic azepine derivatives: Biological evaluation of pyrimido[4,5-b]-1,4-benzoxazepines, thiazepines, and diazepines as inhibitors of the epidermal growth factor receptor tyrosine kinase Journal article
Bioorganic and Medicinal Chemistry Letters, 2006,Volume: 16,Issue: 19,Page: 5102-5106
Authors:  Smith II L.;  Wong W.C.;  Kiselyov A.S.;  Burdzovic-Wizemann S.;  Mao Y.;  Xu Y.;  Duncton M.A.J.;  Kim K.;  Piatnitski E.L.;  Doody J.F.;  Wang Y.;  Rosler R.L.;  Milligan D.;  Columbus J.;  Balagtas C.;  Lee S.P.;  Konovalov A.;  Hadari Y.R.
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Diazepine  Epidermal growth factor receptor  Kinase inhibitor  Oxazepine  Thiazepine  
Tricyclic azepine derivatives: Pyrimido[4,5-b]-1,4-benzoxazepines as a novel class of epidermal growth factor receptor kinase inhibitors Journal article
Bioorganic and Medicinal Chemistry Letters, 2006,Volume: 16,Issue: 6,Page: 1643-1646
Authors:  Smith II L.;  Piatnitski E.L.;  Kiselyov A.S.;  Ouyang X.;  Chen X.;  Burdzovic-Wizemann S.;  Xu Y.;  Wang Y.;  Rosler R.L.;  Patel S.N.;  Chiang H.-H.;  Milligan D.L.;  Columbus J.;  Wong W.C.;  Doody J.F.;  Hadari Y.R.
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Benzoxazepine  Epidermal growth factor receptor  Kinase inhibitor  Kinase selectivity  
Synthesis and structure-activity relationships of 1,2,4-triazoles as a novel class of potent tubulin polymerization inhibitors Journal article
Bioorganic and Medicinal Chemistry Letters, 2005,Volume: 15,Issue: 23,Page: 5154-5159
Authors:  Ouyang X.;  Chen X.;  Piatnitski E.L.;  Kiselyov A.S.;  He H.-Y.;  Mao Y.;  Pattaropong V.;  Yu Y.;  Kim K.H.;  Kincaid J.;  Smith II L.;  Wong W.C.;  Lee S.P.;  Milligan D.L.;  Malikzay A.;  Fleming J.;  Gerlak J.;  Deevi D.;  Doody J.F.;  Chiang H.-H.;  Patel S.N.;  Wang Y.;  Rolser R.L.;  Kussie P.;  Labelle M.;  Tuma M.C.
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1,2,4-Triazole  Antimitotic  Tubulin inhibitor  Tubulin polymerization  Tumor vasculature  Vascular disrupting agent