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Pinostrobin Exerts Neuroprotective Actions in Neurotoxin-Induced Parkinson's Disease Models through Nrf2 Induction Journal article
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2018,Volume: 66,Issue: 31,Page: 8307-8318
Authors:  Li, Chuwen;  Tang, Benqin;  Feng, Yu;  Tang, Fan;  Hoi, Maggie Pui-Man;  Su, Ziren;  Lee, Simon Ming-Yuen
Favorite  |  View/Download:7/0  |  Submit date:2018/10/31
Pinostrobin  Parkinson's Disease  Neurotoxin  Nrf2  
Substantial protection against MPTP-associated Parkinson's neurotoxicity in vitro and in vivo by anti-cancer agent SU4312 via activation of MEF2D and inhibition of MAO-B Journal article
NEUROPHARMACOLOGY, 2017,Volume: 126,Page: 12-24
Authors:  Guo, Baojian;  Hu, Shengquan;  Zheng, Chengyou;  Wang, Hongyu;  Luo, Fangcheng;  Li, Haitao;  Cui, Wei;  Yang, Xifei;  Cui, Guozhen;  Mak, Shinghung;  Choi, Tony Chung-Lit;  Ma, Edmond Dik-Lung;  Wang, Yuqiang;  Lee, Simon Ming Yuen;  Zhang, Zaijun;  Han, Yifan
View  |  Adobe PDF(2766Kb)  |  Favorite  |  View/Download:119/4  |  Submit date:2018/10/31
Parkinson's disease  SU4312  Neuroprotection  Myocyte enhancer factor 2D  Monoamine oxidase-B  
Synergistic effects of Chuanxiong-Chishao herb-pair on promoting angiogenesis at network pharmacological and pharmacodynamic levels Journal article
CHINESE JOURNAL OF INTEGRATIVE MEDICINE, 2017,Volume: 23,Issue: 9,Page: 654-662
Authors:  Wang Yan;  Guo Gang;  Yang Bin-rui;  Xin Qi-qi;  Liao Qi-wen;  Lee Simon Ming-Yuen;  Hu Yuan-jia;  Chen Ke-jj;  Cong Wei-hong
Favorite  |  View/Download:15/0  |  Submit date:2018/10/30
Tetramethylpyrazine  Paeoniflorin  Angiogenesis  Network Pharmacology  
A long-lived phosphorescence iridium(III) complex as a switch on-off-on probe for live zebrafish monitoring of endogenous sulfide generation Journal article
BIOSENSORS & BIOELECTRONICS, 2017,Volume: 94,Page: 575-583
Authors:  Ko, Chung-Nga;  Yang, Chao;  Lin, Sheng;  Li, Shengnan;  Dong, Zhenzhen;  Liu, Jinbiao;  Lee, Simon Ming-Yuen;  Leung, Chung-Hang;  Ma, Dik-Lung
Favorite  |  View/Download:14/0  |  Submit date:2018/10/30
Iridum(Iii) Complex  Endogenous Sulfide Production  Sulfide Detection In livIng Organism  
Small-Sized mPEG PLGA Nanoparticles of Schisantherin A with Sustained Release for Enhanced Brain Uptake and Anti-Parkinsonian Activity Journal article
ACS APPLIED MATERIALS & INTERFACES, 2017,Volume: 9,Issue: 11,Page: 9516-9527
Authors:  Chen, Tongkai;  Li, Chuwen;  Li, Ye;  Yi, Xiang;  Wang, Ruibing;  Lee, Simon Ming-Yuen;  Zheng, Ying
Favorite  |  View/Download:14/0  |  Submit date:2018/10/30
Brain Delivery  Cellular Uptake  Fluorescence Resonance Energy Transfer (Fret)  Mpeg-plga Nanoparticles  Oral Bioavailability  Schisantherin a  
Supramolecular alleviation of cardiotoxicity of a small-molecule kinase inhibitor Journal article
Organic and Biomolecular Chemistry, 2017,Volume: 15,Issue: 38,Page: 8046-8053
Authors:  Yang X.;  Huang Q.;  Bardelang D.;  Wang C.;  Lee S.M.Y.;  Wang R.
Favorite  |  View/Download:5/0  |  Submit date:2018/11/06
Zebrafish models of cardiovascular diseases and their applications in herbal medicine research Journal article
European journal of pharmacology, 2015,Volume: 768,Page: 77-86
Authors:  Sai-Wang Seto;  Hosen Kiat;  Simon M.Y. Lee;  Alan Bensoussan;  Yu-Ting Sun;  Maggie P.M. Hoi;  Dennis Chang
Favorite  |  View/Download:1/0  |  Submit date:2019/01/22
Zebrafish  Chinese Herbal Medicine  Cardiovascular  Animal Model  Review  
VEGFR tyrosine kinase inhibitor II (VRI) induced vascular insufficiency in zebrafish as a model for studying vascular toxicity and vascular preservation Journal article
Toxicology and Applied Pharmacology, 2014,Volume: 280,Issue: 3,Page: 408-420
Authors:  Li S.;  Dang Y.Y.;  Oi Lam Che G.;  Kwan Y.W.;  Chan S.W.;  Leung G.P.H.;  Lee S.M.Y.;  Hoi M.P.M.
Favorite  |  View/Download:3/0  |  Submit date:2018/11/06
Cardiovascular Protective Agents  Cardiovascular Toxicity  Vascular Insufficiency  Zebrafish Model  
Discovery of a natural product-like iNOS inhibitor by molecular docking with potential neuroprotective effects in vivo Journal article
PLoS ONE, 2014,Volume: 9,Issue: 4
Authors:  Zhong H.-J.;  Liu L.-J.;  Chong C.-M.;  Lu L.;  Wang M.;  Chan D.S.-H.;  Chan P.W.H.;  Lee S.M.-Y.;  Ma D.-L.;  Leung C.-H.
Favorite  |  View/Download:4/0  |  Submit date:2018/11/06
The novel tetramethylpyrazine bis-nitrone (TN-2) protects against MPTP/MPP+-induced neurotoxicity via inhibition of mitochondrial-dependent apoptosis Journal article
Journal of Neuroimmune Pharmacology, 2014,Volume: 9,Issue: 2,Page: 245-258
Authors:  Xu D.;  Duan H.;  Zhang Z.;  Cui W.;  Wang L.;  Sun Y.;  Lang M.;  Hoi P.M.;  Han Y.;  Wang Y.;  Lee S.M.
Favorite  |  View/Download:5/0  |  Submit date:2018/11/06
Dopaminergic Neuron  Mitochondrial-dependent Apoptosis  Mptp  Parkinson's Disease