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Sodium tanshinone IIA sulfonate promotes endothelial integrity via regulating VE-cadherin dynamics and RhoA/ROCK-mediated cellular contractility and prevents atorvastatin-induced intracerebral hemorrhage in zebrafish Journal article
TOXICOLOGY AND APPLIED PHARMACOLOGY, 2018,Volume: 350,Page: 32-42
Authors:  Zhou, Zhong-Yan;  Huang, Bin;  Li, Shang;  Huang, Xiao-Hui;  Tang, Jing-Yi;  Kwan, Yiu Wa;  Hoi, Pui Man;  Lee, Simon Ming-Yuen
Favorite | View/Download:39/0 | TC[WOS]:5 TC[Scopus]:9 | Submit date:2018/10/30
Sodium Tanshinone Iia Sulfonate  Salvia Miltiorrhiza  Hemorrhagic Stroke  Atorvastatin  Rock  
Tanshinone I prevents atorvastatin-induced cerebral hemorrhage in zebrafish and stabilizes endothelial cell-cell adhesion by inhibiting. VE-cadherin internalization and actin-myosin contractility Journal article
PHARMACOLOGICAL RESEARCH, 2018,Volume: 128,Page: 389-398
Authors:  Huang, Bin;  Zhou, Zhong-Yan;  Li, Shang;  Huang, Xiao-Hui;  Tang, Jing-Yi;  Hoi, Maggie Pui Man;  Lee, Simon Ming Yuen
Favorite | View/Download:43/0 | TC[WOS]:2 TC[Scopus]:5 | Submit date:2018/10/30
Tanshinone i  Vascular Integrity  Endothelial Cell Adhesion  Hemorrhagic Stroke  Zebrafish  Huvecs  
Discovery of a ROCK inhibitor, FPND, which prevents cerebral hemorrhage through maintaining vascular integrity by interference with VE-cadherin Journal article
CELL DEATH DISCOVERY, 2017,Volume: 3
Authors:  Shang Li;  Nana Ai;  Mingyun Shen;  Yuanye Dang;  Cheong-Meng Chong;  Peichen Pan;  Yiu Wa Kwan;  Shun Wan Chan;  George Pak Heng Leung;  Maggie Pui Man Hoi;  Tingjun Hou;  Simon Ming-Yuen Lee
Favorite | View/Download:252/0 | TC[WOS]:5 TC[Scopus]:8 | Submit date:2020/01/16