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Synthesis and biological evaluation of (R)-3,3,3-trifluoro-2-hydroxy-2methylpropionamides as pyruvate dehydrogenase kinase 1 (PDK1) inhibitors to reduce the growth of cancer cells Conference paper
Authors:  Zhang, Shao-Lin;  Zhang, Wen;  Yang, Zheng;  Hu, Xiaohui;  Tam, Kin Yip
Favorite  |  View/Download:6/0  |  Submit date:2018/10/30
Pyruvate dehydrogenase kinase  Pyruvate dehydrogenase complex  Anti-proliferation  Binding affinity  
Phenyl butyrate inhibits pyruvate dehydrogenase kinase 1 and contributes to its anti-cancer effect Conference paper
EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, Zhuhai, PEOPLES R CHINA, 2016-8-23-26
Authors:  Zhang, Wen;  Zhang, Shao-Lin;  Hu, Xiaohui;  Tam, Kin Yip
Favorite  |  View/Download:13/0  |  Submit date:2018/10/30
Phenyl Butyrate  Cancer  Pyruvate Dehydrogenase  Pyruvate Dehydrogenase Kinase 1  Tumor Metabolism  
Synthesis and biological evaluation of (R)-3,3,3-trifluoro-2-hydroxy-2-methylpropionamides as pyruvate dehydrogenase kinase 1 (PDK1) inhibitors to reduce the growth of cancer cells Journal article
European Journal of Pharmaceutical Sciences, 2017,Volume: 110,Page: 87-92
Authors:  Zhang S.-L.;  Zhang W.;  Yang Z.;  Hu X.;  Tam K.Y.
Favorite  |  View/Download:11/0  |  Submit date:2018/12/18
Anti-proliferation  Binding affinity  Pyruvate dehydrogenase complex  Pyruvate dehydrogenase kinase  
An insight into anti-diabetic properties of dietary phytochemicals Conference paper
PHYTOCHEMISTRY REVIEWS, Fuzhou, PEOPLES R CHINA, APR 07-10, 2017
Authors:  Vinayagam, Ramachandran;  Xiao, Jianbo;  Xu, Baojun
Favorite  |  View/Download:9/0  |  Submit date:2018/10/30
Diabetes Mellitius  Botanical Foods  Phytochemicals  Anti-diabetic  Mechanism