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Development of pyruvate dehydrogenase kinase inhibitors in medicinal chemistry with particular emphasis as anticancer agents Journal article
Drug Discovery Today, 2015,Volume: 20,Issue: 9,Page: 1112-1119
Authors:  Shao-Lin Zhang;  Xiaohui Hu;  Wen Zhang;  Huankai Yao;  Kin Yip Tam
Favorite  |  View/Download:6/0  |  Submit date:2019/01/07
NFκB up-regulation of glucose transporter 3 is essential for hyperactive mammalian target of rapamycin-induced aerobic glycolysis and tumor growth Journal article
Cancer Letters, 2015,Volume: 359,Issue: 1,Page: 97-106
Authors:  Zha X.;  Hu Z.;  Ji S.;  Jin F.;  Jiang K.;  Li C.;  Zhao P.;  Tu Z.;  Chen X.;  Di L.;  Zhou H.;  Zhang H.
Favorite  |  View/Download:4/0  |  Submit date:2018/12/21
Aerobic glycolysis  Glut3  MTOR  NFκB  Tumorigenesis  
Targeting tumor metabolism for cancer treatment: Is pyruvate dehydrogenase kinases (PDKs) a viable anticancer target? Journal article
International Journal of Biological Sciences, 2015,Volume: 11,Issue: 12,Page: 1390-1400
Authors:  Wen Zhang;  Shao-Lin Zhang;  Xiaohui Hu;  Kin Yip Tam
Favorite  |  View/Download:10/0  |  Submit date:2019/01/07
Aerobic Glycolysis  Pyruvate Dehydrogenase Kinases  Tumor Metabolism  Pyruvate Dehydrogenase Complex  
CtBP maintains cancer cell growth and metabolic homeostasis via regulating SIRT4 Journal article
Cell Death and Disease, 2015,Volume: 6,Issue: 1
Authors:  Wang L.;  Zhou H.;  Wang Y.;  Cui G.;  Di L.-J.
Favorite  |  View/Download:5/0  |  Submit date:2018/10/31
Berberine interfered with breast cancer cells metabolism, balancing energy homeostasis Journal article
Anti-Cancer Agents in Medicinal Chemistry, 2015,Volume: 15,Issue: 1,Page: 66
Authors:  Tan W.;  Li N.;  Tan R.;  Zhong Z.;  Suo Z.;  Yang X.;  Wang Y.;  Hu X.
Favorite  |  View/Download:8/0  |  Submit date:2018/10/31
Berberine  Chinese Medicine  Energy Homeostasis  Mcf-7  Reprogramming Metabolism