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Downregulation of Cyclin B1 mediates nagilactone E-induced G2 phase cell cycle arrest in non-small cell lung cancer cells Journal article
EUROPEAN JOURNAL OF PHARMACOLOGY, 2018,Volume: 830,Page: 17-25
Authors:  Zhang, Le-Le;  Feng, Zhe-Ling;  Su, Min-Xia;  Jiang, Xiao-Ming;  Chen, Xiuping;  Wang, Yitao;  Li, Ao;  Lin, Li-Gen;  Lu, Jin-Jian
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Nagilactone e  Non-small Cell Lung Cancer  Cyclin B1  Cell Cycle  Apoptosis  
Authentic compound-free strategy for simultaneous determination of primary coumarins in Peucedani Radix using offline high performance liquid chromatography-nuclear magnetic resonance spectroscopy-tandem mass spectrometry Journal article
ACTA PHARMACEUTICA SINICA B, 2018,Volume: 8,Issue: 4,Page: 645-654
Authors:  Liu, Yao;  Song, Qingqing;  Liu, Wenjing;  Li, Peng;  Li, Jun;  Zhao, Yunfang;  Zhang, Liang;  Tu, Pengfei;  Wang, Yitao;  Song, Yuelin
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Authentic Compound-independent Quantitation  Offline Lcnmrms/ms  Automated Fraction Collection Module  Quantitative H-1 Nmr  Peucedani Radix  Regio-specific Monitoring  
UPLC/Q-TOFMS-Based Metabolomics Approach to Reveal the Protective Role of Other Herbs in An-Gong-Niu-Huang Wan Against the Hepatorenal Toxicity of Cinnabar and Realgar Journal article
FRONTIERS IN PHARMACOLOGY, 2018,Volume: 9
Authors:  Xia, Fangbo;  Li, Ao;  Chai, Yushuang;  Xiao, Xiao;  Wan, Jianbo;  Li, Peng;  Wang, Yitao
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An-gong-niu-huang Wan  Cinnabar  Realgar  Metabonomics  Detoxification  Inflammation  
Integrated work-flow for quantitative metabolome profiling of plants, Peucedani Radix as a case Journal article
ANALYTICA CHIMICA ACTA, 2017,Volume: 953,Page: 40-47
Authors:  Song, Yuelin;  Song, Qingqing;  Liu, Yao;  Li, Jun;  Wan, Jian-Bo;  Wang, Yitao;  Jiang, Yong;  Tu, Pengfei
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Quantitative Metabolome  Integrated Work-flow  Offline Two Dimensional Liquid  Chromatography  Linear Range  Peucedani Radix  Isomer  
Exploring the Existing Drug Space for Novel pTyr Mimetic and SHP2 Inhibitors Journal article
ACS Medicinal Chemistry Letters, 2015,Volume: 6,Issue: 7,Page: 782-786
Authors:  He R.;  Yu Z.-H.;  Zhang R.-Y.;  Wu L.;  Gunawan A.M.;  Lane B.S.;  Shim J.S.;  Zeng L.-F.;  He Y.;  Chen L.;  Wells C.D.;  Liu J.O.;  Zhang Z.-Y.
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anticancer agents  fragment-based library  Protein tyrosine phosphatase  pTyr mimetics  SHP2 inhibitors  
Adiponectin, an Unlocking Adipocytokine Journal article
CARDIOVASCULAR THERAPEUTICS, 2009,Volume: 27,Issue: 1,Page: 59-75
Authors:  Sun, YY;  Xun, KL;  Wang, CG;  Zhao, HY;  Bi, HC;  Chen, XP;  Wang, YT
View  |  Adobe PDF(741Kb)  |  Favorite  |  View/Download:253/6  |  Submit date:2018/11/01
Adiponecitn  Biomarker  Drug Target  Exercise  Gender Difference  Inflammation  
High throughput solubility determination with application to selection of compounds for fragment screening Journal article
Bioorganic and Medicinal Chemistry, 2008,Volume: 16,Issue: 13,Page: 6611-6616
Authors:  Colclough N.;  Hunter A.;  Kenny P.W.;  Kittlety R.S.;  Lobedan L.;  Tam K.Y.;  Timms M.A.
Favorite  |  View/Download:4/0  |  Submit date:2018/12/18
Automation  Fragment Screening  Fragment-based Drug Discovery  Physicochemical Properties  Screening Library  Solubility  Structure-property Relationship  Uv/vis Spectroscopy