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Vascular endothelial growth factor gene transfer therapy for coronary artery disease: A systematic review and meta-analysis Journal article
CARDIOVASCULAR THERAPEUTICS, 2018,Volume: 36,Issue: 5
Authors:  Yuan, Rong;  Xin, Qiqi;  Shi, Weili;  Liu, Wei;  Lee, Simon-M.;  Hoi, Puiman;  Li, Lin;  Zhao, Jun;  Cong, Weihong;  Chen, Keji
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Angina Pectoris  Angiogenesis Inducing Agents  Coronary Artery Disease  Genetic Therapy  Myocardial Ischemia  Vascular Endothelial Growth Factor  
Water soluble fraction from ethanolic extract of Clausena lansium seeds alleviates obesity and insulin resistance, and changes the composition of gut microbiota in high-fat diet-fed mice Journal article
JOURNAL OF FUNCTIONAL FOODS, 2018,Volume: 47,Page: 192-199
Authors:  Shen, Shengnan;  Liao, Qiwen;  Huang, Li;  Li, Dan;  Zhang, Qingwen;  Wang, Yitao;  Lee, Simon Ming-Yuen;  Lin, Ligen
View  |  Adobe PDF(1563Kb)  |  Favorite  |  View/Download:591/37  |  Submit date:2018/10/30
Clausena Lansium  Fat Mass Gain  Insulin Sensitivity  Gut Microbiota  Wampee  
N-Propargyl Caffeamide (PACA) Ameliorates Dopaminergic Neuronal Loss and Motor Dysfunctions in MPTP Mouse Model of Parkinson's Disease and in MPP+-Induced Neurons via Promoting the Conversion of proNGF to NGF Journal article
MOLECULAR NEUROBIOLOGY, 2018,Volume: 55,Issue: 3,Page: 2258-2267
Authors:  Luo, Dan;  Zhao, Jia;  Cheng, Yuanyuan;  Lee, Simon Ming-Yuen;  Rong, Jianhui
Favorite  |  View/Download:10/0  |  Submit date:2018/10/31
Parkinson's disease  Neuroprotection  N-propargyl caffeamide (PACA)  NGF/TrkApathway  PI3K/Akt  ERK1/2  
Substantial protection against MPTP-associated Parkinson's neurotoxicity in vitro and in vivo by anti-cancer agent SU4312 via activation of MEF2D and inhibition of MAO-B Journal article
NEUROPHARMACOLOGY, 2017,Volume: 126,Page: 12-24
Authors:  Guo, Baojian;  Hu, Shengquan;  Zheng, Chengyou;  Wang, Hongyu;  Luo, Fangcheng;  Li, Haitao;  Cui, Wei;  Yang, Xifei;  Cui, Guozhen;  Mak, Shinghung;  Choi, Tony Chung-Lit;  Ma, Edmond Dik-Lung;  Wang, Yuqiang;  Lee, Simon Ming Yuen;  Zhang, Zaijun;  Han, Yifan
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Parkinson's disease  SU4312  Neuroprotection  Myocyte enhancer factor 2D  Monoamine oxidase-B  
Potent Protection Against MPP+ -Induced Neurotoxicity via Activating Transcription Factor MEF2D by a Novel Derivative of Naturally Occurring Danshensu/Tetramethylpyrazine Journal article
NEUROMOLECULAR MEDICINE, 2016,Volume: 18,Issue: 4,Page: 561-572
Authors:  Shengquan Hu;  Liang Wang;  Shinghung Mak;  Zaijun Zhang;  Daping Xu;  Haitao Li;  Yide Li;  Yuanjia Hu;  Simon Ming Yuen Lee;  Yuqiang Wang;  Yifan Han
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Parkinson’s Disease  Mef2d  Neuroprotection  Mpp++++  Gsk3β  Danshensu/tetramethylpyrazine Derivative  
Discovery, synthesis, and functional characterization of a novel neuroprotective natural product from the fruit of alpinia oxyphylla for use in Parkinson's disease through LC/MS-based multivariate data analysis-guided fractionation Journal article
Journal of Proteome Research, 2016,Volume: 15,Issue: 8,Page: 2595-2606
Authors:  Guohui Li;  Zaijun Zhang;  Quan Quan;  Renwang Jiang;  Samuel S.W. Szeto;  Shuai Yuan;  Wing-tak Wong;  Herman H. C. Lam;  Simon Ming-Yuen Lee;  Ivan K. Chu
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Natural Products  Neuroprotective  Nrf2  Parkinson's Disease  Proteomics  
Examining the neuroprotective effects of protocatechuic acid and chrysin on in vitro and in vivo models of Parkinson disease Journal article
Free Radical Biology and Medicine, 2015,Volume: 84,Page: 331
Authors:  Zaijun Zhang;  Guohui Li;  Samuel S.W. Szeto;  Cheong Meng Chong;  Quan Quan;  Chen Huang;  Wei Cui;  Baojian Guo;  Yuqiang Wang;  Yifan Han;  K.W. Michael Siu;  Simon Ming Yuen Lee;  Ivan K. Chu
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Anti-inflammation  Freeradicals  Neuroprotection  Nrf2 Nf-κb  Parkinsondisease  Proteomics  
Unexpected Neuronal Protection of SU5416 against 1-Methyl-4-Phenylpyridinium Ion-Induced Toxicity via Inhibiting Neuronal Nitric Oxide Synthase Journal article
PLoS ONE, 2012,Volume: 7,Issue: 9
Authors:  Cui W.;  Zhang Z.;  Li W.;  Mak S.;  Hu S.;  Zhang H.;  Yuan S.;  Rong J.;  Choi T.C.;  Lee S.M.Y.;  Han Y.
Favorite  |  View/Download:6/0  |  Submit date:2018/11/06
Pro-angiogenic activity of astragaloside IV in HUVECs in vitro and zebrafish in vivo Journal article
Molecular Medicine Reports, 2012,Volume: 5,Issue: 3,Page: 805-811
Authors:  Yi Zhang;  Guang Hu;  Shang Li;  Zhen Hua Li;  Che Oi Lam;  Si-Jia Hong;  iu‑Wa Kwan;  Shun Wan Chan;  George Pak-Heng Leung;  Simon Ming-Yuen Lee
Favorite  |  View/Download:22/0  |  Submit date:2018/10/30
Angiogenesis  Astragaloside Iv  Human Umbilical Vein Endothelial Cell  Radix Astragali  Zebrafish  
Resveratrol derivative, trans-3,5,4′-trimethoxystilbene, exerts antiangiogenic and vascular-disrupting effects in zebrafish through the downregulation of VEGFR2 and cell-cycle modulation Journal article
Journal of Cellular Biochemistry, 2010,Volume: 109,Issue: 2,Page: 339
Authors:  Alex D.;  Leong E.C.;  Zhang Z.-J.;  Yan G.T.H.;  Cheng S.-H.;  Leong C.-W.;  Li Z.-H.;  Lam K.-H.;  Chan S.-W.;  Lee S.M.-Y.
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3,5,4′-trimethoxystilbene  Angiogenesis  Cell Cycle  Huvec  Vegfr2  Zebrafish