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Downregulation of Cyclin B1 mediates nagilactone E-induced G2 phase cell cycle arrest in non-small cell lung cancer cells Journal article
EUROPEAN JOURNAL OF PHARMACOLOGY, 2018,Volume: 830,Page: 17-25
Authors:  Zhang, Le-Le;  Feng, Zhe-Ling;  Su, Min-Xia;  Jiang, Xiao-Ming;  Chen, Xiuping;  Wang, Yitao;  Li, Ao;  Lin, Li-Gen;  Lu, Jin-Jian
View  |  Adobe PDF(3226Kb)  |  Favorite  |  View/Download:254/23  |  Submit date:2018/10/30
Nagilactone e  Non-small Cell Lung Cancer  Cyclin B1  Cell Cycle  Apoptosis  
2-methoxy-6-acetyl-7-methyljuglone (MAM) induces iNOS/NO-mediated DNA damage response through activation of MAPKs pathways Journal article
Anti-Cancer Agents in Medicinal Chemistry, 2018,Volume: 18,Issue: 6,Page: 903-913
Authors:  Niu Y.;  Yuan R.;  Gao H.;  Lu J.-J.;  Kong Q.;  Chen X.
Favorite  |  View/Download:6/0  |  Submit date:2018/12/28
Atm/chk2  Dna Damage  Inos/no  L-arginine  Mam  Mapks  
Investigational Hypoxia-Activated Prodrugs: Making Sense of Future Development Journal article
Current Drug Targets, 2018,Volume: 20
Authors:  Min-Xia Su;  Le-Le Zhang;  Zhang-Jian Huang;  Jia-Jie Shi;  Jin-Jian Lu
Favorite  |  View/Download:2/0  |  Submit date:2019/01/14
Hypoxia-activated Prodrug  Topoisomerase Ii Inhibitors  Dna Alkylating Agents  Targeted Drugs  Reductases Activity  Patient Selection  Clinical Progress  
Osthole inhibited TGF beta-induced epithelial-mesenchymal transition (EMT) by suppressing NF-kappa B mediated Snail activation in lung cancer A549 cells Journal article
CELL ADHESION & MIGRATION, 2017,Volume: 11,Issue: 5-6,Page: 464-475
Authors:  Feng, Haitao;  Lu, Jin-Jian;  Wang, Yitao;  Pei, Lixia;  Chen, Xiuping
View  |  Adobe PDF(1506Kb)  |  Favorite  |  View/Download:175/8  |  Submit date:2018/10/30
Emt  Nf-kappa b  Osthole Snail  Tgf-beta 1  
PK11195-chitosan-graft-polyethylenimine-modified SPION as a mitochondria-targeting gene carrier Journal article
Journal of Drug Targeting, 2016,Volume: 24,Issue: 5,Page: 457-467
Authors:  Kim Y.-K.;  Zhang M.;  Lu J.-J.;  Xu F.;  Chen B.-A.;  Xing L.;  Jiang H.-L.
Favorite  |  View/Download:5/0  |  Submit date:2018/12/28
Gene Therapy  Magnetofection  Mitochondria-targeting  Non-viral Vector  Superparamagnetic Iron Oxide Nanoparticles  
A luminescent G-quadruplex-selective iridium(iii) complex for the label-free detection of lysozyme Journal article
Journal of Materials Chemistry B, 2016,Volume: 4,Issue: 14,Page: 2407-2411
Authors:  Lu L.;  Wang W.;  Wang M.;  Kang T.-S.;  Lu J.-J.;  Chen X.-P.;  Han Q.-B.;  Leung C.-H.;  Ma D.-L.
Favorite  |  View/Download:4/0  |  Submit date:2018/11/06
Codelivery of Doxorubicin and shAkt1 by Poly(ethylenimine)-Glycyrrhetinic Acid Nanoparticles to Induce Autophagy-Mediated Liver Cancer Combination Therapy Journal article
Molecular Pharmaceutics, 2016,Volume: 13,Issue: 4,Page: 1298-1307
Authors:  Wang F.-Z.;  Xing L.;  Tang Z.-H.;  Lu J.-J.;  Cui P.-F.;  Qiao J.-B.;  Jiang L.;  Jiang H.-L.;  Zong L.
Favorite  |  View/Download:1/0  |  Submit date:2018/12/28
Autophagy  Combination Therapy  Glycyrrhetinic Acid  Liver Cancer Targeting  Self-assembled  
A novel dinuclear iridium(III) complex as a G-quadruplex-selective probe for the luminescent switch-on detection of transcription factor HIF-1α Journal article
Scientific Reports, 2016,Volume: 6
Authors:  Lu L.;  Wang M.;  Mao Z.;  Kang T.-S.;  Chen X.-P.;  Lu J.-J.;  Leung C.-H.;  Ma D.-L.
Favorite  |  View/Download:5/0  |  Submit date:2018/11/06
Ethanol enhances cucurbitacin B-induced apoptosis by inhibiting cucurbitacin B-induced autophagy in LO2 hepatocytes Journal article
Molecular and Cellular Toxicology, 2016,Volume: 12,Issue: 1,Page: 29-36
Authors:  Ding Q.;  Bao J.;  Zhao W.;  Lu J.;  Zhu H.;  Chen X.
Favorite  |  View/Download:3/0  |  Submit date:2018/12/28
Apoptosis  Autophagy  Cucurbitacin b  Ethanol  Hepatocyte  
PTEN activation by DNA damage induces protective autophagy in response to Cucurbitacin B in hepatocellular carcinoma cells Journal article
Oxidative Medicine and Cellular Longevity, 2016,Volume: 2016
Authors:  Niu Y.;  Sun W.;  Lu J.-J.;  Ma D.-L.;  Leung C.-H.;  Pei L.;  Chen X.
Favorite  |  View/Download:8/0  |  Submit date:2018/11/06