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Toosendanin, a natural product, inhibited TGF-1-induced epithelial-mesenchymal transition through ERK/Snail pathway Journal article
PHYTOTHERAPY RESEARCH, 2018,Volume: 32,Issue: 10,Page: 2009-2020
Authors:  Luo, Weiwei;  Liu, Xin;  Sun, Wen;  Lu, Jin-Jian;  Wang, Yitao;  Chen, Xiuping
View  |  Adobe PDF(2621Kb)  |  Favorite  |  View/Download:497/30  |  Submit date:2018/10/30
Emt  Erk1/2  Snail  Lung Cancer  Toosendanin  
Downregulation of Cyclin B1 mediates nagilactone E-induced G2 phase cell cycle arrest in non-small cell lung cancer cells Journal article
EUROPEAN JOURNAL OF PHARMACOLOGY, 2018,Volume: 830,Page: 17-25
Authors:  Zhang, Le-Le;  Feng, Zhe-Ling;  Su, Min-Xia;  Jiang, Xiao-Ming;  Chen, Xiuping;  Wang, Yitao;  Li, Ao;  Lin, Li-Gen;  Lu, Jin-Jian
View  |  Adobe PDF(3226Kb)  |  Favorite  |  View/Download:257/23  |  Submit date:2018/10/30
Nagilactone e  Non-small Cell Lung Cancer  Cyclin B1  Cell Cycle  Apoptosis  
Diethyl blechnic, a novel natural product isolated from salvia miltiorrhiza bunge, inhibits doxorubicin-induced apoptosis by inhibiting ROS and activating JNK1/2 Journal article
International Journal of Molecular Sciences, 2018,Volume: 19,Issue: 6
Authors:  Yu J.;  Gao H.;  Wu C.;  Xu Q.-M.;  Lu J.-J.;  Chen X.
Favorite  |  View/Download:5/0  |  Submit date:2018/12/28
Cardiotoxicity  Diethyl Blechnic  Dox  Jnk1/2  Ros  
Garcinone E induces apoptosis and inhibits migration and invasion in ovarian cancer cells Journal article
SCIENTIFIC REPORTS, 2017,Volume: 7
Authors:  Xu, Xiao-Huang;  Liu, Qian-Yu;  Li, Ting;  Liu, Jian-Lin;  Chen, Xin;  Huang, Li;  Qiang, Wen-An;  Chen, Xiuping;  Wang, Yitao;  Lin, Li-Gen;  Lu, Jin-Jian
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Induction of reactive oxygen species-stimulated distinctive autophagy by chelerythrine in non-small cell lung cancer cells Journal article
REDOX BIOLOGY, 2017,Volume: 12,Page: 367-376
Authors:  Tang, Zheng-Hai;  Cao, Wen-Xiang;  Wang, Zhao-Yu;  Lu, Jia-Hong;  Liu, Bo;  Chen, Xiuping;  Lu, Jin-Jian
Favorite  |  View/Download:12/0  |  Submit date:2018/10/30
Chelerythrine  Autophagy  Apoptosis  Ros  Nsclc  
Osimertinib induces autophagy and apoptosis via reactive oxygen species generation in non-small cell lung cancer cells Journal article
TOXICOLOGY AND APPLIED PHARMACOLOGY, 2017,Volume: 321,Page: 18-26
Authors:  Tang, Zheng-Hai;  Cao, Wen-Xiang;  Su, Min-Xia;  Chen, Xiuping;  Lu, Jin-Jian
Favorite  |  View/Download:13/0  |  Submit date:2018/10/30
Osimertinib  Azd9291  Autophagy  Apoptosis  Ros  
Osthole inhibited TGF beta-induced epithelial-mesenchymal transition (EMT) by suppressing NF-kappa B mediated Snail activation in lung cancer A549 cells Journal article
CELL ADHESION & MIGRATION, 2017,Volume: 11,Issue: 5-6,Page: 464-475
Authors:  Feng, Haitao;  Lu, Jin-Jian;  Wang, Yitao;  Pei, Lixia;  Chen, Xiuping
View  |  Adobe PDF(1506Kb)  |  Favorite  |  View/Download:179/8  |  Submit date:2018/10/30
Emt  Nf-kappa b  Osthole Snail  Tgf-beta 1  
Baicalein Induces Beclin 1-and Extracellular Signal-Regulated Kinase-Dependent Autophagy in Ovarian Cancer Cells Journal article
AMERICAN JOURNAL OF CHINESE MEDICINE, 2017,Volume: 45,Issue: 1,Page: 123-136
Authors:  Wang, Ya-Fang;  Xu, Yu-Lian;  Tang, Zheng-Hai;  Li, Ting;  Zhang, Le-Le;  Chen, Xiuping;  Lu, Jia-Hong;  Leung, Chung-Hang;  Ma, Dik-Lung;  Qiang, Wen-An;  Wang, Yi-Tao;  Lu, Jin-Jian
Favorite  |  View/Download:17/0  |  Submit date:2018/10/30
Baicalein  Ovarian Cancer  Autophagy  Beclin 1  Erk  
Ethanol enhances cucurbitacin B-induced apoptosis by inhibiting cucurbitacin B-induced autophagy in LO2 hepatocytes Journal article
Molecular and Cellular Toxicology, 2016,Volume: 12,Issue: 1,Page: 29-36
Authors:  Ding Q.;  Bao J.;  Zhao W.;  Lu J.;  Zhu H.;  Chen X.
Favorite  |  View/Download:3/0  |  Submit date:2018/12/28
Apoptosis  Autophagy  Cucurbitacin b  Ethanol  Hepatocyte  
Cucurbitacin B inhibits proliferation, induces G2/M cycle arrest and autophagy without affecting apoptosis but enhances MTT reduction in PC12 cells Journal article
Bangladesh Journal of Pharmacology, 2016,Volume: 11,Issue: 1,Page: 110-118
Authors:  Wu C.;  Bao J.;  He C.;  Lu J.;  Chen X.
Favorite  |  View/Download:2/0  |  Submit date:2018/12/28
Apoptosis  Autophagy  Cucurbitacin b  G2/m Cycle  Mtt  Pc12 Cell