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SIRT1 deacetylates TopBP1 and modulates intra-sphase checkpoint and DNA replication origin firing Journal article
International Journal of Biological Sciences, 2014,Volume: 10,Issue: 10,Page: 1193-1202
Authors:  Wang R.-H.;  Lahusen T.J.;  Chen Q.;  Xu X.;  Miller Jenkins L.M.;  Leo E.;  Fu H.;  Aladjem M.;  Pommier Y.;  Appella E.;  Deng C.-X.
Favorite  |  View/Download:7/0  |  Submit date:2018/12/13
Dna Replication Fork  Genetic Stability  Intra-s-phase Checkpoint  Sirt1  Topbp1  
Induction of angiogenesis in zebrafish embryos and proliferation of endothelial cells by an active fraction isolated from the root of astragalus membranaceus using bioassay-guided fractionation Journal article
Journal of Traditional and Complementary Medicine, 2014,Volume: 4,Issue: 4,Page: 239-245
Authors:  Lai P.;  Chan J.;  Kwok H.-F.;  Cheng L.;  Yu H.;  Lau C.-P.;  Leung P.-C.;  Fung K.-P.;  Lau C.
Favorite  |  View/Download:2/0  |  Submit date:2019/01/17
Astragali Radix  Glycoproteins  Traditional Chinese Medicine  Wound healing  
Identification of an old antibiotic clofoctol as a novel activator of unfolded protein response pathways and an inhibitor of prostate cancer Journal article
British Journal of Pharmacology, 2014,Volume: 171,Issue: 19,Page: 4478-4489
Authors:  Wang M.;  Shim J.S.;  Li R.-J.;  Dang Y.;  He Q.;  Das M.;  Liu J.O.
Favorite  |  View/Download:3/0  |  Submit date:2019/01/15
Chemopreventive effects of oplopantriol A, a novel compound isolated from oplopanax horridus, on colorectal cancer Journal article
Nutrients, 2014,Volume: 6,Issue: 7,Page: 2668-2680
Authors:  Zhang Z.;  Yu C.;  Zhang C.-F.;  Wu X.-H.;  Wen X.-D.;  Anderson S.;  Yuan C.-S.;  Du W.;  Huang W.-H.;  Li S.-P.;  Wang C.-Z.
Favorite  |  View/Download:3/0  |  Submit date:2018/11/06
Apoptosis  Cell Cycle  Chemoprevention  Colorectal Cancer  Death Receptor Signaling Pathway  Hct-116  Oplopanax Horridus  Oplopantriol a  Opt a  Sw-480  Tumor Necrosis Factors  
Drug repurposing screen identifies lestaurtinib amplifies the ability of the poly (ADP-ribose) polymerase 1 inhibitor AG14361 to kill breast cancer associated gene-1 mutant and wild type breast cancer cells Journal article
Breast Cancer Research, 2014,Volume: 16,Issue: 3
Authors:  Vazquez-Ortiz G.;  Chisholm C.;  Xu X.;  Lahusen T.J.;  Li C.;  Sakamuru S.;  Huang R.;  Thomas C.J.;  Xia M.;  Deng C.
Favorite  |  View/Download:7/0  |  Submit date:2018/12/13
Metabolic characterization of (+/-)-praeruptorin A in vitro and in vivo by high performance liquid chromatography coupled with hybrid triple quadrupole-linear ion trap mass spectrometry and time-of-fl Journal article
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2014,Volume: 90,Issue: 5,Page: 98-110
Authors:  Song, Yue-Lin;  Jing, Wang-Hui;  Yan, Ru;  Wang, Yi-Tao
View  |  Adobe PDF(3404Kb)  |  Favorite  |  View/Download:55/7  |  Submit date:2018/11/01
(+/-)-praeruptorin a  Metabolism  Lightsight (Tm) Software  In Vivo  Peucedani Radix  
H-1 nuclear magnetic resonance based-metabolomic characterization of Peucedani Radix and simultaneous determination of praeruptorin A and praeruptorin B Journal article
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2014,Volume: 93,Issue: SI,Page: 86-94
Authors:  Song, Yue-Lin;  Jing, Wang-Hui;  Chen, Yan-Gan;  Yuan, Yun-Fei;  Yan, Ru;  Wang, Yi-Tao
View  |  Adobe PDF(1142Kb)  |  Favorite  |  View/Download:102/15  |  Submit date:2018/11/01
Peucedani Radix  Metabolomic Profile  Quantitative H-1 Nmr  Praeruptorin a  Praeruptorin b  
Simultaneously enantiospecific determination of (+)-trans-khellactone, (+/-)-praeruptorin A, (+/-)-praeruptorin B, (+)-praeruptorin E, and their metabolites, (+/-)-cis-khellactone, in rat plasma using Journal article
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2014,Volume: 88,Issue: 1,Page: 269-277
Authors:  Song, Yuelin;  Jing, Wanghui;  Yang, Fengqing;  Shi, Zhan;  Yao, Meicun;  Yan, Ru;  Wang, Yitao
View  |  Adobe PDF(488Kb)  |  Favorite  |  View/Download:101/13  |  Submit date:2018/11/01
Online Spe  Chiral Lc-ms/ms  Enantiospecific  Peucedani Radix  Pharmacokinetics  
Snail1-dependent control of embryonic stem cell pluripotency and lineage commitment Journal article
Nature Communications, 2014,Volume: 5
Authors:  Lin Y.;  Li X.-Y.;  Willis A.L.;  Liu C.;  Chen G.;  Weiss S.J.
Favorite  |  View/Download:2/0  |  Submit date:2018/12/21
Emodin elicits cytotoxicity in human lung adenocarcinoma A549 cells through inducing apoptosis Journal article
Inflammopharmacology, 2014,Volume: 22,Issue: 2,Page: 127-134
Authors:  Li W.-Y.;  Ng Y.-F.;  Zhang H.;  Guo Z.-D.;  Guo D.-J.;  Kwan Y.-W.;  Leung G.P.-H.;  Lee S.M.-Y.;  Yu P.H.-F.;  Chan S.-W.
Favorite  |  View/Download:3/0  |  Submit date:2018/11/06
Cell cycle arrest  DNA fragmentation  Emodin  Growth inhibition