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Neuroprotective Effects of BHDPC, a Novel Neuroprotectant, on Experimental Stroke by Modulating Microglia Polarization
Journal article
ACS CHEMICAL NEUROSCIENCE, 2019,Volume: 10,Issue: 5,Page: 2434-2449
Authors:
Chuwen Li
;
Yaqi Bian
;
Yu Feng
;
Fan Tang
;
Liang Wang
;
Maggie Pui Man Hoi
;
Dan Ma
;
Chao Zhao
;
Simon Ming Yuen Lee
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View/Download:231/0
|
TC[WOS]:
4
TC[Scopus]:
10
|
Submit date:2020/01/16
Bhdpc
Ischemic Stroke
Microglia
Nf-κb
Creb
Pka
Sodium tanshinone IIA sulfonate promotes endothelial integrity via regulating VE-cadherin dynamics and RhoA/ROCK-mediated cellular contractility and prevents atorvastatin-induced intracerebral hemorrhage in zebrafish
Journal article
TOXICOLOGY AND APPLIED PHARMACOLOGY, 2018,Volume: 350,Page: 32-42
Authors:
Zhou, Zhong-Yan
;
Huang, Bin
;
Li, Shang
;
Huang, Xiao-Hui
;
Tang, Jing-Yi
;
Kwan, Yiu Wa
;
Hoi, Pui Man
;
Lee, Simon Ming-Yuen
Favorite
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View/Download:39/0
|
TC[WOS]:
5
TC[Scopus]:
9
|
Submit date:2018/10/30
Sodium Tanshinone Iia Sulfonate
Salvia Miltiorrhiza
Hemorrhagic Stroke
Atorvastatin
Rock
Substantial protection against MPTP-associated Parkinson's neurotoxicity in vitro and in vivo by anti-cancer agent SU4312 via activation of MEF2D and inhibition of MAO-B
Journal article
NEUROPHARMACOLOGY, 2017,Volume: 126,Page: 12-24
Authors:
Guo, Baojian
;
Hu, Shengquan
;
Zheng, Chengyou
;
Wang, Hongyu
;
Luo, Fangcheng
;
Li, Haitao
;
Cui, Wei
;
Yang, Xifei
;
Cui, Guozhen
;
Mak, Shinghung
;
Choi, Tony Chung-Lit
;
Ma, Edmond Dik-Lung
;
Wang, Yuqiang
;
Lee, Simon Ming Yuen
;
Zhang, Zaijun
;
Han, Yifan
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View/Download:533/13
|
TC[WOS]:
7
TC[Scopus]:
13
|
Submit date:2018/10/31
Parkinson's disease
SU4312
Neuroprotection
Myocyte enhancer factor 2D
Monoamine oxidase-B
Zebrafish: A promising in vivo model for assessing the delivery of natural products, fluorescence dyes and drugs across the blood-brain barrier
Journal article
PHARMACOLOGICAL RESEARCH, 2017,Volume: 125,Page: 246-257
Authors:
Li, Ye
;
Chen, Tongkai
;
Miao, Xiaoqing
;
Yi, Xiang
;
Wang, Xueqing
;
Zhao, Haitao
;
Lee, Simon Ming-Yuen
;
Zheng, Ying
Favorite
|
View/Download:39/0
|
TC[WOS]:
12
TC[Scopus]:
20
|
Submit date:2018/10/30
Blood Brain Barrier (Bbb)
Zebrafish
Fluorescence Dyes
Natural Products
Drug Delivery Systems
Permeability
Pluronic P85/F68 Micelles of Baicalein Could Interfere with Mitochondria to Overcome MRP2-Mediated Efflux and Offer Improved Anti-Parkinsonian Activity
Journal article
Molecular Pharmaceutics, 2017,Volume: 14,Issue: 10,Page: 3331-3342
Authors:
Tongkai Chen
;
Ye Li
;
Chuwen Li
;
Xiang Yi
;
Ruibing Wang
;
Simon Ming-Yuen Lee
;
Ying Zheng
Favorite
|
View/Download:21/0
|
TC[WOS]:
8
TC[Scopus]:
14
|
Submit date:2018/11/06
Baicalein
Fluorescence Resonance Energy Transfer (Fret)
Micelles
Mitochondria
Multidrug Resistance-associated Protein 2 (Mrp2)
Neuroprotective Effect
Zebrafish as a visual and dynamic model to study the transport of nanosized drug delivery systems across the biological barriers
Journal article
Colloids and Surfaces B: Biointerfaces, 2017,Volume: 156,Page: 227-235
Authors:
Li Y.
;
Miao X.
;
Chen T.
;
Yi X.
;
Wang R.
;
Zhao H.
;
Lee S.M.-Y.
;
Wang X.
;
Zheng Y.
Favorite
|
View/Download:18/0
|
TC[WOS]:
16
TC[Scopus]:
20
|
Submit date:2018/11/06
Biological Barriers
Nanocrystals
Transport
Zebrafish
Small-Sized mPEG PLGA Nanoparticles of Schisantherin A with Sustained Release for Enhanced Brain Uptake and Anti-Parkinsonian Activity
Journal article
ACS APPLIED MATERIALS & INTERFACES, 2017,Volume: 9,Issue: 11,Page: 9516-9527
Authors:
Chen, Tongkai
;
Li, Chuwen
;
Li, Ye
;
Yi, Xiang
;
Wang, Ruibing
;
Lee, Simon Ming-Yuen
;
Zheng, Ying
Favorite
|
View/Download:78/0
|
TC[WOS]:
21
TC[Scopus]:
34
|
Submit date:2018/10/30
Brain Delivery
Cellular Uptake
Fluorescence Resonance Energy Transfer (Fret)
Mpeg-plga Nanoparticles
Oral Bioavailability
Schisantherin a
Tetramethylpyrazine nitrone, a multifunctional neuroprotective agent for ischemic stroke therapy
Journal article
Scientific Reports, 2016,Volume: 6
Authors:
Zaijun Zhang
;
Gaoxiao Zhang
;
Yewei Sun
;
Samuel S. W. Szeto
;
Henry C. H. Law
;
Quan Quan
;
Guohui Li
;
Pei Yu
;
Eiketsu Sho
;
Michael K. W. Siu
;
Simon M. Y. Lee
;
Ivan K. Chu
;
Yuqiang Wang
Favorite
|
View/Download:18/0
|
TC[WOS]:
11
TC[Scopus]:
22
|
Submit date:2018/11/06
A microfluidic linear node array for the study of protein-ligand interactions
Journal article
Lab on a Chip, 2014,Volume: 14,Issue: 20,Page: 3993-3999
Authors:
Li C.-W.
;
Yu G.
;
Jiang J.
;
Lee S.M.-Y.
;
Yi C.
;
Yue W.
;
Yang M.
Favorite
|
View/Download:15/0
|
TC[WOS]:
1
TC[Scopus]:
1
|
Submit date:2018/11/06
Unexpected Neuronal Protection of SU5416 against 1-Methyl-4-Phenylpyridinium Ion-Induced Toxicity via Inhibiting Neuronal Nitric Oxide Synthase
Journal article
PLoS ONE, 2012,Volume: 7,Issue: 9
Authors:
Cui W.
;
Zhang Z.
;
Li W.
;
Mak S.
;
Hu S.
;
Zhang H.
;
Yuan S.
;
Rong J.
;
Choi T.C.
;
Lee S.M.Y.
;
Han Y.
Favorite
|
View/Download:10/0
|
TC[WOS]:
18
TC[Scopus]:
21
|
Submit date:2018/11/06