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Targeting cancer metabolism to develop human lactate dehydrogenase (hLDH)5 inhibitors Journal article
DRUG DISCOVERY TODAY, 2018,Volume: 23,Issue: 7,Page: 1407-1415
Authors:  Zhang, Shao-Lin;  He, Yun;  Tam, Kin Yip
Favorite  |  View/Download:11/0  |  Submit date:2018/10/30
Development of pyruvate dehydrogenase kinase inhibitors in medicinal chemistry with particular emphasis as anticancer agents Journal article
Drug Discovery Today, 2015,Volume: 20,Issue: 9,Page: 1112-1119
Authors:  Shao-Lin Zhang;  Xiaohui Hu;  Wen Zhang;  Huankai Yao;  Kin Yip Tam
Favorite  |  View/Download:2/0  |  Submit date:2019/01/07
Discovery of 4-{4-[(3R)-3-methylmorpholin-4-yl]-6-[1-(methylsulfonyl) cyclopropyl]pyrimidin-2-yl}-1H-indole (AZ20): A potent and selective inhibitor of ATR protein kinase with monotherapy in vivo antitumor activity Journal article
Journal of Medicinal Chemistry, 2013,Volume: 56,Issue: 5,Page: 2125-2138
Authors:  Foote K.M.;  Blades K.;  Cronin A.;  Fillery S.;  Guichard S.S.;  Hassall L.;  Hickson I.;  Jacq X.;  Jewsbury P.J.;  McGuire T.M.;  Nissink J.W.M.;  Odedra R.;  Page K.;  Perkins P.;  Suleman A.;  Tam K.;  Thommes P.;  Broadhurst R.;  Wood C.
Favorite  |  View/Download:3/0  |  Submit date:2018/12/18