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Effects of insulin on transcriptional response and permeability in an in vitro model of human blood-brain barrier Journal article
JOURNAL OF CELLULAR BIOCHEMISTRY, 2018,Volume: 119,Issue: 7,Page: 5657-5664
作者:  Kuai, Ziyu;  Xu, Yan;  Zhao, Qi;  Liu, Jie;  Guan, Shanshan;  Qiao, Yongbo;  Gong, Xin;  Nie, Jiaojiao;  Li, Pengju;  Liu, Dongni;  Xing, Yifan;  Li, Huiwen;  Sun, Zixiao;  Wang, Wenqi;  Ning, Chunan;  Shi, Yuhua;  Kong, Wei;  Shan, Yaming
收藏  |  浏览/下载:22/0  |  提交时间:2018/10/30
Alzheimer's Disease  Human Blood-brain Barrier  Insulin  Type 2 Diabetes  Transcriptional Response  Permeability  
SLOH, a carbazole-based fluorophore, mitigates neuropathology and behavioral impairment in the triple-transgenic mouse model of Alzheimer's disease Journal article
NEUROPHARMACOLOGY, 2018,Volume: 131,Page: 351-363
作者:  Wu, Xiaoli;  Kosaraju, Jayasankar;  Zhou, Wei;  Tam, Kin Yip
收藏  |  浏览/下载:8/0  |  提交时间:2018/10/31
Amyloid beta  Aggregation  Alzheimer's disease  3xTg-AD  Neuroprotection  SH-SY5Y  
Human amyloid β peptide and tau co-expression impairs behavior and causes specific gene expression changes in Caenorhabditis elegans Journal article
Neurobiology of Disease, 2018,Volume: 109,Page: 88-101
作者:  Wang C.;  Saar V.;  Leung K.L.;  Chen L.;  Wong G.
收藏  |  浏览/下载:6/0  |  提交时间:2018/12/18
Alzheimer's Disease  Amyloid Beta  Caenorhabditis Elegans  Rna Interference  Tau  Transcriptome Analysis  
Systemic clearance and brain distribution of carbazole-based cyanine compounds as Alzheimer's disease drug candidates Journal article
SCIENTIFIC REPORTS, 2017,Volume: 7
作者:  Zhou, Wei;  Hu, Xiaohui;  Tam, Kin Yip
收藏  |  浏览/下载:11/0  |  提交时间:2018/10/31
Linagliptin, a Dipeptidyl Peptidase-4 Inhibitor, Mitigates Cognitive Deficits and Pathology in the 3xTg-AD Mouse Model of Alzheimer's Disease Journal article
MOLECULAR NEUROBIOLOGY, 2017,Volume: 54,Issue: 8,Page: 6074-6084
作者:  Kosaraju, Jayasankar;  Holsinger, R. M. Damian;  Guo, Lixia;  Tam, Kin Yip
收藏  |  浏览/下载:4/0  |  提交时间:2018/10/31
Glucagon-like peptide-1  Glucose-dependent insulinotropic polypeptide  Amyloid beta  Tau phosphorylation  Neuroinflammation  
Modulating the phenotype of host macrophages to enhance osteogenesis in MSC-laden hydrogels: Design of a glucomannan coating material Journal article
BIOMATERIALS, 2017,Volume: 139,Page: 39-55
作者:  Niu, Yiming;  Li, Qiu;  Xie, Ruiyu;  Liu, Shang;  Wang, Ruibing;  Xing, Panfei;  Shi, Yuchen;  Wang, Yitao;  Dong, Lei;  Wang, Chunming
浏览  |  Adobe PDF(5330Kb)  |  收藏  |  浏览/下载:131/11  |  提交时间:2018/10/30
Bioactive Coating  Glucomannan Polysaccharides  Scaffold-tissue Integration  Macrophages  Osteogenesis  
Artemisinin protects PC12 cells against β-amyloid-induced apoptosis through activation of the ERK1/2 signaling pathway Journal article
Redox Biology, 2017,Volume: 12,Page: 625-633
作者:  Zeng Z.;  Xu J.;  Zheng W.
收藏  |  浏览/下载:2/0  |  提交时间:2018/12/21
Alzheimer's Disease  Artemisinin  Aβ25–35  Erk1/2  Pc12 Cells  
Neuroprotective Effect of SLM, a Novel Carbazole-Based Fluorophore, on SH-SY5Y Cell Model and 3xTg-AD Mouse Model of Alzheimer’s Disease Journal article
ACS Chemical Neuroscience, 2017,Volume: 8,Issue: 3,Page: 676-685
作者:  Wu X.;  Kosaraju J.;  Zhou W.;  Tam K.Y.
收藏  |  浏览/下载:8/0  |  提交时间:2018/12/18
3xtg-ad  Aggregation  Alzheimer’s Disease  Amyloid β  Neuroprotection  Sh-sy5y  Slm  
Chemical and Physical Approaches for the Treatment of Alzheimer's Disease Journal article
ADMET & DMPK, 2015,Volume: 3,Issue: 3,Page: 216-234
作者:  Jing Li;  WeiZhou;  Xiaoli Wu;  KinTam
收藏  |  浏览/下载:0/0  |  提交时间:2019/01/07
Alzheimer’s Disease  Β-amyloid Peptide  Tau Protein  Pharmacological Strategies  Deep Brain Stimulation  Neurobiological Pathogenesis  
Adult and neonatal astrocytes exhibit diverse gene expression profiles in response to beta amyloid ex vivo Journal article
World Journal of Neuroscience, 2012,Volume: 2,Issue: 2,Page: 57-67
作者:  Antti Kurronen;  Rea Pihlaja;  Eveliina Pollari;  Katja Kanninen;  Markus Storvik;  Garry Wong;  Milla Koistinaho;  Jari Koistinaho
收藏  |  浏览/下载:8/0  |  提交时间:2019/01/04
Alzheimer’s Disease  Astrocytes  Mice  Amyloid Beta  Gene Expression  Microarray Analysis  Endocytosis  Proteolysis