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Insulin-like growth factor-1 activates PI3K/Akt signalling to protect human retinal pigment epithelial cells from amiodarone-induced oxidative injury Journal article
BRITISH JOURNAL OF PHARMACOLOGY, 2018,Volume: 175,Issue: 1,Page: 125-139
Authors:  Liao, Rifang;  Yan, Fengxia;  Zeng, Zhuanping;  Wang, Haitao;  Qiu, Kaifeng;  Xu, Jinying;  Zheng, Wenhua
Favorite  |  View/Download:14/0  |  Submit date:2018/10/30
A dual-specific IGF-I/II human engineered antibody domain inhibits IGF signaling in breast cancer cells Journal article
International Journal of Biological Sciences, 2018,Volume: 14,Issue: 7,Page: 799–806
Authors:  Zhizhen Chen;  Jie Liu;  Dafeng Chu;  Yaming Shan;  Guixing Ma;  Hongmin Zhang;  Xiaohua Douglas Zhang;  Pu Wang;  Qiang Chen;  Chuxia Deng;  Weizao Chen;  Dimiter Dimitrov;  Qi Zhao
Favorite  |  View/Download:7/0  |  Submit date:2018/12/17
Insulin-like Growth Factor  Yeast Display  Affinity Maturation  Ead  
Discovery and preliminary SAR of 14-aryloxy-andrographolide derivatives as antibacterial agents with immunosuppressant activity Journal article
RSC ADVANCES, 2018,Volume: 8,Issue: 17,Page: 9440-9456
Authors:  Li, Feng;  Li, Xiao-Min;  Sheng, Dekuan;  Chen, Shao-Ru;  Nie, Xin;  Liu, Zhuyun;  Wang, Decai;  Zhao, Qi;  Wang, Yitao;  Wang, Ying;  Zhou, Guo-Chun
View  |  Adobe PDF(583Kb)  |  Favorite  |  View/Download:300/13  |  Submit date:2018/10/30
Amiodarone-Induced Retinal Neuronal Cell Apoptosis Attenuated by IGF-1 via Counter Regulation of the PI3k/Akt/FoxO3a Pathway Journal article
MOLECULAR NEUROBIOLOGY, 2017,Volume: 54,Issue: 9,Page: 6931-6943
Authors:  Liao, Rifang;  Yan, Fengxia;  Zeng, Zhuanping;  Farhan, Mohd;  Little, Peter;  Quirion, Remi;  Srivastava, Lalit K.;  Zheng, Wenhua
Favorite  |  View/Download:12/0  |  Submit date:2018/10/30
Amiodarone  Foxo3a  Akt  Antiarrhythmic  Apoptosis  Neuroprotection  
H2O2 attenuates IGF-1R tyrosine phosphorylation and its survival signaling properties in neuronal cells via NR2B containing NMDA receptor Journal article
ONCOTARGET, 2017,Volume: 8,Issue: 39,Page: 65313-65328
Authors:  Zeng, Zhiwen;  Wang, Dejun;  Gaur, Uma;  Liao Rifang;  Wang, Haitao;  Zheng, Wenhua
Favorite  |  View/Download:10/0  |  Submit date:2018/10/30
H2o2  Sh-sy5y  Nr2b  Nmda  Igf-1r  
Differential regulation of kit ligand A (kitlga) expression in the zebrafish ovarian follicle cells - Evidence for the existence of a cyclic adenosine 3 ', 5 ' monophosphate-mediated binary regulatory system during folliculogenesis Journal article
MOLECULAR AND CELLULAR ENDOCRINOLOGY, 2015,Volume: 402,Issue: C,Page: 21-31
Authors:  Yao, Kai;  Ge, Wei
Favorite  |  View/Download:6/0  |  Submit date:2018/12/10
Kit Ligand a  Camp  Pka  Epac  Ovary  Zebrafish  
A new bispecific antibody targeting non-overlapping epitopes on IGF2: Design, in vitro characterization and pharmacokinetics in macaques Journal article
Experimental and Molecular Pathology, 2014,Volume: 97,Issue: 3,Page: 359-367
Authors:  Feng Y.;  Zhao Q.;  Chen W.;  Wang Y.;  Crowder K.;  Dimitrov D.S.
Favorite  |  View/Download:4/0  |  Submit date:2019/01/16
Bispecific Antibodies  Cynomolgus Macaques  Half-life  Igf Ligand  
The type 2 diabetes mellitus susceptibility gene IGF2BP2 is associated with schizophrenia in a Han Chinese Population Journal article
Journal of Clinical Psychiatry, 2013,Volume: 74,Issue: 4
Authors:  Zhang X.;  Hui L.;  Liu Y.;  Wang Z.-Q.;  You Y.;  Miao L.-N.;  Sun S.-L.;  Guan S.-L.;  Xiang Y.;  Kosten T.R.;  Zhang X.Y.
Favorite  |  View/Download:1/0  |  Submit date:2018/12/18
Thermal stability of fibroblast growth factor protein is a determinant factor in regulating self-renewal, differentiation, and reprogramming in human pluripotent stem cells Journal article
Stem Cells, 2012,Volume: 30,Issue: 4,Page: 623-630
Authors:  Chen G.;  Gulbranson D.R.;  Yu P.;  Hou Z.;  Thomson J.A.
Favorite  |  View/Download:3/0  |  Submit date:2018/12/21
Differentiation  Fibroblast Growth Factor  Map Kinase  Pluripotency  Pluripotent Stem Cells  Thermal Stability  
Proline-rich Akt substrate of 40 kDa (PRAS40): A novel downstream target of PI3k/Akt signaling pathway Journal article
CELLULAR SIGNALLING, 2012,Volume: 24,Issue: 1,Page: 17-24
Authors:  Wang, HT;  Zhang, QS;  Wen, Q;  Zheng, YX;  Philip, L;  Jiang, H;  Lin, J;  Zheng, WH
Favorite  |  View/Download:6/0  |  Submit date:2019/01/10
Pras40  Tumorigenesis  Insulin Resistance  Pi3k/akt  Mtorc1