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Deciphering the Pharmacological Mechanisms of the Huayu-Qiangshen-Tongbi Formula Through Integrating Network Pharmacology and In Vitro Pharmacological Investigation Journal article
FRONTIERS IN PHARMACOLOGY, 2019,Volume: 10
Authors:  Zihao Wang;  Ke-Gang Linghu;  Yuanjia Hu;  Huali Zuo;  Hao Yi;  Shi-Hang Xiong;  Jinjian Lu;  Ging Chan;  Hua Yu;  Run-Yue Huang
Favorite  |  View/Download:1/0  |  Submit date:2019/12/04
Rheumatoid Arthritis  Network Pharmacology  Traditional Chinese Medicine  Huayu-qiangshen-tongbi Formula  In Vitro Validation  
Downregulation of Cyclin B1 mediates nagilactone E-induced G2 phase cell cycle arrest in non-small cell lung cancer cells Journal article
EUROPEAN JOURNAL OF PHARMACOLOGY, 2018,Volume: 830,Page: 17-25
Authors:  Zhang, Le-Le;  Feng, Zhe-Ling;  Su, Min-Xia;  Jiang, Xiao-Ming;  Chen, Xiuping;  Wang, Yitao;  Li, Ao;  Lin, Li-Gen;  Lu, Jin-Jian
View  |  Adobe PDF(3226Kb)  |  Favorite  |  View/Download:156/21  |  Submit date:2018/10/30
Nagilactone e  Non-small Cell Lung Cancer  Cyclin B1  Cell Cycle  Apoptosis  
Garcinone E induces apoptosis and inhibits migration and invasion in ovarian cancer cells Journal article
SCIENTIFIC REPORTS, 2017,Volume: 7
Authors:  Xu, Xiao-Huang;  Liu, Qian-Yu;  Li, Ting;  Liu, Jian-Lin;  Chen, Xin;  Huang, Li;  Qiang, Wen-An;  Chen, Xiuping;  Wang, Yitao;  Lin, Li-Gen;  Lu, Jin-Jian
View  |  Adobe PDF(5330Kb)  |  Favorite  |  View/Download:128/10  |  Submit date:2018/10/30
Cytosolic calcium mediates RIP1/RIP3 complex-dependent necroptosis through JNK activation and mitochondrial ROS production in human colon cancer cells Journal article
FREE RADICAL BIOLOGY AND MEDICINE, 2017,Volume: 108,Page: 433-444
Authors:  Sun, Wen;  Wu, Xiaxia;  Gao, Hongwei;  Yu, Jie;  Zhao, Wenwen;  Lu, Jin-Jian;  Wang, Jinhua;  Du, Guanhua;  Chen, Xiuping
Favorite  |  View/Download:11/0  |  Submit date:2018/10/30
Necroptosis  C-jun N-terminal Kinase  Calcium  Ros  
Osthole inhibited TGF beta-induced epithelial-mesenchymal transition (EMT) by suppressing NF-kappa B mediated Snail activation in lung cancer A549 cells Journal article
CELL ADHESION & MIGRATION, 2017,Volume: 11,Issue: 5-6,Page: 464-475
Authors:  Feng, Haitao;  Lu, Jin-Jian;  Wang, Yitao;  Pei, Lixia;  Chen, Xiuping
View  |  Adobe PDF(1506Kb)  |  Favorite  |  View/Download:78/7  |  Submit date:2018/10/30
Emt  Nf-kappa b  Osthole Snail  Tgf-beta 1  
Alkaloids Isolated from Natural Herbs as the Anticancer Agents Journal article
EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE, 2012,Issue: 4,Page: 623-644
Authors:  Lu, JJ (Lu, Jin-Jian);  Bao, JL (Bao, Jiao-Lin);  Chen, XP (Chen, Xiu-Ping);  HHuang, M (Huang, Min);  Wang, YT (Wang, Yi-Tao)
View  |  Adobe PDF(2331Kb)  |  Favorite  |  View/Download:107/12  |  Submit date:2018/11/01
Cell-cycle Arrest  Sanguinarine-induced Apoptosis  Suppresses Tumor-growth  Swiss Albino Mice  Matrine Inhibits Proliferation  Hepatocellular-carcinoma Cells  Mediated Multidrug-resistance  Buccal Pouch Carcinogenesis  Berberine-induced Apoptosis  Induced Lung Carcinogenesis  
Multi-Target Drugs: The Trend of Drug Research and Development Journal article
PLOS ONE, 2012,Volume: 7,Issue: 6,Page: 30-46
Authors:  Lu, JJ (Lu, Jin-Jian);  Pan, W (Pan, Wei);  Hu, YJ (Hu, Yuan-Jia);  Wang, YT (Wang, Yi-Tao
View  |  Adobe PDF(1050Kb)  |  Favorite  |  View/Download:84/3  |  Submit date:2018/11/01
Cancer-therapy  Alzheimers-disease  Parkinsons-disease  Attractive Target  Natural-products  b Inhibitors  Discovery  Atherosclerosis  Acetylcholinesterase  Proliferation