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Cyclin B1 stability is increased by interaction with BRCA1, and its overexpression suppresses the progression of BRCA1-associated mammary tumors Journal article
Experimental and Molecular Medicine, 2018,Volume: 50,Page: 136
Authors:  Choi, Eun Kyung;  Lim, Jeong-A;  Kim, Jong Kwang;  Jang, Moon Sun;  Kim, Sun Eui;  Baek, Hye Jung;  Park, Eun Jung;  Kim, Tae Hyun;  Deng, Chu-Xia;  Wang, Rui-Hong;  Kim, Sang Soo
Favorite | View/Download:36/0 | TC[WOS]:2 TC[Scopus]:0 | Submit date:2018/10/30
BRCA1 deficiency sensitizes breast cancer cells to bromodomain and extra-terminal domain (BET) inhibition Journal article
Oncogene, 2018,Issue: 37,Page: 6341–6356
Authors:  Baoyuan Zhang;  Junfang Lyu;  Yifan Liu;  Changjie Wu;  Eun Ju Yang;  Lakhansing Pardeshi;  Kaeling Tan;  Koon Ho Wong;  Qiang Chen;  Xiaoling Xu;  Chu-Xia Deng;  Joong Sup Shim
Favorite | View/Download:29/0 | TC[WOS]:2 TC[Scopus]:0 | Submit date:2018/12/17
Single-cell RNA-Seq reveals cell heterogeneity and hierarchy within mouse mammary epithelia Journal article
JOURNAL OF BIOLOGICAL CHEMISTRY, 2018,Volume: 293,Issue: 22,Page: 8315-8329
Authors:  Sun, Heng;  Miao, Zhengqiang;  Zhang, Xin;  Chan, Un In;  Su, Sek Man;  Guo, Sen;  Wong, Chris Koon Ho;  Xu, Xiaoling;  Deng, Chu-Xia
Favorite | View/Download:57/0 | TC[WOS]:6 TC[Scopus]:0 | Submit date:2018/10/30
Mammary Gland  Development  Breast Cancer  Biomarker  Cell Differentiation  Stem Cells  cdh5+cell  Mammary Stem Cells (Mascs)  Single Cell Rna-seq  
BRCA1 function in the intra-S checkpoint is activated by acetylation via a pCAF/SIRT1 axis Journal article
ONCOGENE, 2018,Volume: 37,Issue: 17,Page: 2343-2350
Authors:  Lahusen, Tyler J.;  Kim, Seung-Jin;  Miao, Kai;  Huang, Zebin;  Xu, Xiaoling;  Deng, Chu-Xia
Favorite | View/Download:31/0 | TC[WOS]:6 TC[Scopus]:0 | Submit date:2018/10/30
Inhibition of Estrogen Signaling Reduces the Incidence of BRCA1-associated Mammary Tumor Formation Journal article
International journal of biological sciences, 2018,Volume: 14,Issue: 12,Page: 1755-1768
Authors:  Baek H.J.;  Kim S.E.;  Choi E.K.;  Kim J.K.;  Shin D.H.;  Park E.J.;  Kim T.H.;  Kim J.-Y.;  Kim K.G.;  Deng C.-X.;  Kim S.S.
Favorite | View/Download:12/0 | TC[WOS]:1 TC[Scopus]:0 | Submit date:2018/12/13
Brca1  Cancer Prevention  Estrogen  Fulvestrant  
Inhibition of AKT suppresses the initiation and progression of BRCA1-associated mammary tumors Journal article
International journal of biological sciences, 2018,Volume: 14,Issue: 13,Page: 1769-1781
Authors:  Baek H.J.;  Kim S.E.;  Kim J.K.;  Shin D.H.;  Kim T.H.;  Kim K.G.;  Deng C.-X.;  Kim S.S.
Favorite | View/Download:11/0 | TC[WOS]:3 TC[Scopus]:0 | Submit date:2018/12/13
Akt  Brca1  Mk-2206  Precision Medicine  
A dual-specific IGF-I/II human engineered antibody domain inhibits IGF signaling in breast cancer cells Journal article
International Journal of Biological Sciences, 2018,Volume: 14,Issue: 7,Page: 799–806
Authors:  Zhizhen Chen;  Jie Liu;  Dafeng Chu;  Yaming Shan;  Guixing Ma;  Hongmin Zhang;  Xiaohua Douglas Zhang;  Pu Wang;  Qiang Chen;  Chuxia Deng;  Weizao Chen;  Dimiter Dimitrov;  Qi Zhao
Favorite | View/Download:15/0 | TC[WOS]:3 TC[Scopus]:0 | Submit date:2018/12/17
Insulin-like Growth Factor  Yeast Display  Affinity Maturation  Ead  
A comprehensive genomic meta-analysis identifies confirmatory role of OBSCN gene in breast tumorigenesis Journal article
ONCOTARGET, 2017,Volume: 8,Issue: 60,Page: 102263-102276
Authors:  Rajendran, Barani Kumar;  Deng, Chu-Xia
Favorite | View/Download:24/0 | TC[WOS]:1 TC[Scopus]:0 | Submit date:2018/10/30
Breast Cancer  Obscn Gene  Obscurin  Cell Adhesion  Emt  
Potential therapeutic targets of triple-negative breast cancer based on its intrinsic subtype Journal article
ONCOTARGET, 2017,Volume: 8,Issue: 42,Page: 73329-73344
Authors:  Shao, Fangyuan;  Sun, Heng;  Deng, Chu-Xia
Favorite | View/Download:20/0 | TC[WOS]:25 TC[Scopus]:0 | Submit date:2018/10/30
Cancer Therapy  Tnbc Subtype  Cscs  Drug Resistance  Cancer Targets  
Characterization of potential driver mutations involved in human breast cancer by computational approaches Journal article
ONCOTARGET, 2017,Volume: 8,Issue: 30,Page: 50252-50272
Authors:  Rajendran, Barani Kumar;  Deng, Chu-Xia
Favorite | View/Download:20/0 | TC[WOS]:14 TC[Scopus]:0 | Submit date:2018/10/30
Driver Mutations  Breast Cancer  Cancer Drivers  Breast Cancer Driver Genes  Genetic Mutations