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Downregulation of Cyclin B1 mediates nagilactone E-induced G2 phase cell cycle arrest in non-small cell lung cancer cells Journal article
EUROPEAN JOURNAL OF PHARMACOLOGY, 2018,Volume: 830,Page: 17-25
Authors:  Zhang, Le-Le;  Feng, Zhe-Ling;  Su, Min-Xia;  Jiang, Xiao-Ming;  Chen, Xiuping;  Wang, Yitao;  Li, Ao;  Lin, Li-Gen;  Lu, Jin-Jian
View  |  Adobe PDF(3226Kb)  |  Favorite  |  View/Download:143/20  |  Submit date:2018/10/30
Nagilactone e  Non-small Cell Lung Cancer  Cyclin B1  Cell Cycle  Apoptosis  
Targeting the Hsp90-Cdc37-client protein interaction to disrupt Hsp90 chaperone machinery Journal article
JOURNAL OF HEMATOLOGY & ONCOLOGY, 2018,Volume: 11
Authors:  Li, Ting;  Jiang, Hu-Lin;  Tong, Yun-Guang;  Lu, Jin-Jian
Favorite  |  View/Download:14/0  |  Submit date:2018/10/30
Hsp90 Chaperone Machinery  Cdc37  Kinase Client  Protein Interaction  
Garcinone E induces apoptosis and inhibits migration and invasion in ovarian cancer cells Journal article
SCIENTIFIC REPORTS, 2017,Volume: 7
Authors:  Xu, Xiao-Huang;  Liu, Qian-Yu;  Li, Ting;  Liu, Jian-Lin;  Chen, Xin;  Huang, Li;  Qiang, Wen-An;  Chen, Xiuping;  Wang, Yitao;  Lin, Li-Gen;  Lu, Jin-Jian
View  |  Adobe PDF(5330Kb)  |  Favorite  |  View/Download:99/9  |  Submit date:2018/10/30
Novel Hsp90 inhibitor platycodin D disrupts Hsp90/Cdc37 complex and enhances the anticancer effect of mTOR inhibitor Journal article
TOXICOLOGY AND APPLIED PHARMACOLOGY, 2017,Volume: 330,Page: 65-73
Authors:  Li, Ting;  Chen, Xin;  Dai, Xiao-Yang;  Wei, Bin;  Weng, Qin-Jie;  Chen, Xiuping;  Ouyang, De-Fang;  Yan, Ru;  Huang, Zhang-Jian;  Jiang, Hu-Lin;  Zhu, Hong;  Lu, Jin-Jian
Favorite  |  View/Download:7/0  |  Submit date:2018/10/30
Everolimus  Platycodin d  Hsp90  Cdc37  Egfr  Igf1r  
Chikusetsusaponin IVa methyl ester induces G1 cell cycle arrest, triggers apoptosis and inhibits migration and invasion in ovarian cancer cells Journal article
PHYTOMEDICINE, 2017,Volume: 29,Page: E1-E1
Authors:  Chen, Xin;  Wu, Qiu-Shuang;  Meng, Fan-Cheng;  Tang, Zheng-Hai;  Chen, Xiuping;  Lin, Li-Gen;  Chen, Ping;  Qiang, Wen-An;  Wang, Yi-Tao;  Zhang, Qing-Wen;  Lu, Jin-Jian
Favorite  |  View/Download:16/0  |  Submit date:2018/10/30
Osthole inhibited TGF beta-induced epithelial-mesenchymal transition (EMT) by suppressing NF-kappa B mediated Snail activation in lung cancer A549 cells Journal article
CELL ADHESION & MIGRATION, 2017,Volume: 11,Issue: 5-6,Page: 464-475
Authors:  Feng, Haitao;  Lu, Jin-Jian;  Wang, Yitao;  Pei, Lixia;  Chen, Xiuping
View  |  Adobe PDF(1506Kb)  |  Favorite  |  View/Download:66/7  |  Submit date:2018/10/30
Emt  Nf-kappa b  Osthole Snail  Tgf-beta 1  
Cytotoxic and pro-apoptotic effects of cassane diterpenoids from the seeds of Caesalpinia sappan in cancer cells Journal article
Molecules, 2016,Volume: 21,Issue: 6
Authors:  Bao H.;  Zhang L.-L.;  Liu Q.-Y.;  Feng L.;  Ye Y.;  Lu J.-J.;  Lin L.-G.
Favorite  |  View/Download:3/0  |  Submit date:2018/12/28
Caesalpinia Sappan  Cassane Diterpenoids  Cytotoxicity  Apoptosis  P53  
Cucurbitacin B inhibits proliferation, induces G2/M cycle arrest and autophagy without affecting apoptosis but enhances MTT reduction in PC12 cells Journal article
Bangladesh Journal of Pharmacology, 2016,Volume: 11,Issue: 1,Page: 110-118
Authors:  Wu C.;  Bao J.;  He C.;  Lu J.;  Chen X.
Favorite  |  View/Download:2/0  |  Submit date:2018/12/28
Apoptosis  Autophagy  Cucurbitacin b  G2/m Cycle  Mtt  Pc12 Cell  
Effects of alisol B 23-acetate on ovarian cancer cells: G1 phase cell cycle arrest, apoptosis, migration and invasion inhibition Journal article
Phytomedicine, 2016,Volume: 23,Issue: 8,Page: 800
Authors:  Zhang L.-L.;  Xu Y.-L.;  Tang Z.-H.;  Xu X.-H.;  Chen X.;  Li T.;  Ding C.-Y.;  Huang M.-Q.;  Chen X.-P.;  Wang Y.-T.;  Yuan X.-F.;  Lu J.-J.
Favorite  |  View/Download:5/0  |  Submit date:2018/10/31
Alisol b 23-acetate  Apoptosis  Cell Cycle Arrest  Invasion  Migration  Ovarian Cancer  
A Systematic Review of the Anticancer Properties of Compounds Isolated from Licorice (Gancao) Journal article
Planta Medica, 2015,Volume: 81,Issue: 18,Page: 1670-1687
Authors:  Tang ZH;  Li T;  Tong YG;  Chen XJ;  Chen XP;  Wang YT;  Lu JJ
Favorite  |  View/Download:8/0  |  Submit date:2019/01/07
Glycyrrhiza Glabra  Leguminosae  Licorice  Anticancer  Mechanism  Triterpenoids  Flavonoids