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Substantial protection against MPTP-associated Parkinson's neurotoxicity in vitro and in vivo by anti-cancer agent SU4312 via activation of MEF2D and inhibition of MAO-B Journal article
NEUROPHARMACOLOGY, 2017,Volume: 126,Page: 12-24
Authors:  Guo, Baojian;  Hu, Shengquan;  Zheng, Chengyou;  Wang, Hongyu;  Luo, Fangcheng;  Li, Haitao;  Cui, Wei;  Yang, Xifei;  Cui, Guozhen;  Mak, Shinghung;  Choi, Tony Chung-Lit;  Ma, Edmond Dik-Lung;  Wang, Yuqiang;  Lee, Simon Ming Yuen;  Zhang, Zaijun;  Han, Yifan
View  |  Adobe PDF(2766Kb)  |  Favorite  |  View/Download:213/5  |  Submit date:2018/10/31
Parkinson's disease  SU4312  Neuroprotection  Myocyte enhancer factor 2D  Monoamine oxidase-B  
Cleavable Multifunctional Targeting Mixed Micelles with Sequential pH-Triggered TAT Peptide Activation for Improved Antihepatocellular Carcinoma Efficacy Journal article
MOLECULAR PHARMACEUTICS, 2017,Volume: 14,Issue: 11,Page: 3644-3659
Authors:  Zhang, Jinming;  Zheng, Yifeng;  Xie, Xi;  Wang, Lan;  Su, Ziren;  Wang, Yitao;  Leong, Kam W.;  Chen, Meiwan
View  |  Adobe PDF(2484Kb)  |  Favorite  |  View/Download:487/46  |  Submit date:2018/10/30
Tumor-targeting  Glycyrrhetinic Acid  Ph-sensitive  Tat Exposure  Mixed Micelles  
SIRT3 protects hepatocytes from oxidative injury by enhancing ROS scavenging and mitochondrial integrity Journal article
CELL DEATH & DISEASE, 2017,Volume: 8
Authors:  Liu, Jingxin;  Li, Dan;  Zhang, Tian;  Tong, Qiang;  Ye, Richard Dequan;  Lin, Ligen
Favorite  |  View/Download:16/0  |  Submit date:2018/10/30
Triphenylphosphonium-modified poly(ethylene glycol)-poly(epsilon-caprolactone) micelles for mitochondria- targeted gambogic acid delivery Journal article
INTERNATIONAL JOURNAL OF PHARMACEUTICS, 2017,Volume: 522,Issue: 1-2,Page: 21-33
Authors:  Xu, Yingqi;  Wang, Shengpeng;  Chan, Hon Fai;  Liu, Yuling;  Li, Hui;  He, Chengwei;  Li, Zeyong;  Chen, Meiwan
Favorite  |  View/Download:13/0  |  Submit date:2018/10/30
Gambogic Acid  Polymeric Micelles  Mitochondrial Targeting  Lung Cancer  
Tert-butyl hydroperoxide (t-BHP) induced apoptosis and necroptosis in endothelial cells: Roles of NOX4 and mitochondrion Journal article
REDOX BIOLOGY, 2017,Volume: 11,Page: 524-534
Authors:  Zhao, Wenwen;  Feng, Haitao;  Sun, Wen;  Liu, Kang;  Lu, Jin-Jian;  Chen, Xiuping
Favorite  |  View/Download:11/0  |  Submit date:2018/10/30
Apoptosis  Necroptosis  Reactive Oxygen Species  Nox4  Mitochondria  Endothelial Cells