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Substantial protection against MPTP-associated Parkinson's neurotoxicity in vitro and in vivo by anti-cancer agent SU4312 via activation of MEF2D and inhibition of MAO-B Journal article
NEUROPHARMACOLOGY, 2017,Volume: 126,Page: 12-24
Authors:  Guo, Baojian;  Hu, Shengquan;  Zheng, Chengyou;  Wang, Hongyu;  Luo, Fangcheng;  Li, Haitao;  Cui, Wei;  Yang, Xifei;  Cui, Guozhen;  Mak, Shinghung;  Choi, Tony Chung-Lit;  Ma, Edmond Dik-Lung;  Wang, Yuqiang;  Lee, Simon Ming Yuen;  Zhang, Zaijun;  Han, Yifan
View  |  Adobe PDF(2766Kb)  |  Favorite  |  View/Download:119/4  |  Submit date:2018/10/31
Parkinson's disease  SU4312  Neuroprotection  Myocyte enhancer factor 2D  Monoamine oxidase-B  
Zebrafish models of cardiovascular diseases and their applications in herbal medicine research Journal article
European journal of pharmacology, 2015,Volume: 768,Page: 77-86
Authors:  Sai-Wang Seto;  Hosen Kiat;  Simon M.Y. Lee;  Alan Bensoussan;  Yu-Ting Sun;  Maggie P.M. Hoi;  Dennis Chang
Favorite  |  View/Download:2/0  |  Submit date:2019/01/22
Zebrafish  Chinese Herbal Medicine  Cardiovascular  Animal Model  Review  
Nanosuspension Development of scutellarein as an active and rapid orally absorbed precursor of its BCS class IV glycoside scutellarin Journal article
Journal of Pharmaceutical Sciences, 2014,Volume: 103,Issue: 11,Page: 3576-3584
Authors:  Yang X.;  Miao X.;  Cao F.;  Li S.;  Ai N.;  Chang Q.I.;  Lee S.M.Y.;  Zheng Y.
Favorite  |  View/Download:5/0  |  Submit date:2018/11/06
Absorption  Cerebral Hemorrhage  Metabolism  Nanotechnology  Oral Drug Delivery  Precursor  Scutellarin (Sg)  Solubility  Zebrafish  
Discovery of a benzofuran derivative (MBPTA) as a novel ROCK inhibitor that protects against MPP+-induced oxidative stress and cell death in SH-SY5Y cells Journal article
Free Radical Biology and Medicine, 2014,Volume: 74,Page: 283-293
Authors:  Chong C.-M.;  Shen M.;  Zhou Z.-Y.;  Pan P.;  Hoi P.-M.;  Li S.;  Liang W.;  Ai N.;  Zhang L.-Q.;  Li C.-W.;  Yu H.;  Hou T.;  Lee S.M.-Y.
Favorite  |  View/Download:8/0  |  Submit date:2018/11/06
Benzofuran  Free Radicals  No  Parkinson Disease  Rock  Ros  
Peptide fingerprinting of the neurotoxic fractions isolated from the secretions of sea anemones Stichodactyla helianthus and Bunodosoma granulifera. New members of the APETx-like family identified by a 454 pyrosequencing approach Journal article
Peptides, 2012,Volume: 34,Issue: 1,Page: 26
Authors:  Rodríguez A.A.;  Cassoli J.S.;  Sa F.;  Dong Z.Q.;  De Freitas J.C.;  Pimenta A.M.C.;  De Lima M.E.;  Konno K.;  Lee S.M.Y.;  Garateix A.;  Zaharenko A.J.
Favorite  |  View/Download:4/0  |  Submit date:2018/10/30
454 Sequencing  Bunodosoma Granulifera  Peptide Fingerprint  Peptidomics  Sea Anemone  Stichodactyla Helianthus  Toxin  Transcriptomics  Venom  
Panax notoginseng Reduces Atherosclerotic Lesions in ApoE-Deficient Mice and Inhibits TNF-alpha-Induced Endothelial Adhesion Molecule Expression and Monocyte Adhesion Journal article
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2009,Volume: 57,Issue: 15,Page: 6692-6697
Authors:  Wan, JB;  Lee, SMY;  Wang, JD;  Wang, N;  He, CW;  Wang, YT;  Kang, JX
View  |  Adobe PDF(1493Kb)  |  Favorite  |  View/Download:122/9  |  Submit date:2018/11/01
Panax Notoginseng  Atherosclerosis  Inflammation  Apoe-deficient Mice  Adhesion Molecules