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Identification and pharmaceutical evaluation of novel frog skin-derived serine proteinase inhibitor peptide PE-BBI (Pelophylax esculentus Bowman-Birk inhibitor) for the potential treatment of cancer Journal article
SCIENTIFIC REPORTS, 2018,Volume: 8
Authors:  Lyu, Peng;  Ge, Lilin;  Ma, Rui;  Wei, Ran;  McCrudden, Cian M.;  Chen, Tianbao;  Shaw, Chris;  Kwok, Hang Fai
Favorite  |  View/Download:12/0  |  Submit date:2018/10/30
Triggering of cancer cell cycle arrest by a novel scorpion venom-derived peptide-Gonearrestide Journal article
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE, 2018,Volume: 22,Issue: 9,Page: 4460-4473
Authors:  Li, Bin;  Lyu, Peng;  Xi, Xinping;  Ge, Lilin;  Mahadevappa, Ravikiran;  Shaw, Chris;  Kwok, Hang Fai
Favorite  |  View/Download:10/0  |  Submit date:2018/10/30
Anticancer Mechanism  Binding Sites  Ms  Ms Proteome  Ngs Transcriptome  Signalling Pathways  Venom Library  
Evaluation in zebrafish model of the toxicity of rhodamine B-conjugated crotamine, a peptide potentially useful for diagnostics and therapeutics Journal article
JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY, 2017,Volume: 31,Issue: 11
Authors:  Chan, Judy Yuet-Wa;  Zhou, Hefeng;  Kwan, Yiu Wa;  Chan, Shun Wan;  Radis-Baptista, Gandhi;  Lee, Simon Ming-Yuen
Favorite  |  View/Download:20/0  |  Submit date:2018/10/30
acute toxicity  rhodamine B-crotamine  screening of pharmaceuticals  venom-derived peptides  zebrafish model  
The structure of helokinestatin-5 and its biosynthetic precursor from Gila monster (Heloderma suspectum) venom: Evidence for helokinestatin antagonism of bradykinin-induced relaxation of rat tail artery smooth muscle Journal article
Peptides, 2010,Volume: 31,Issue: 8,Page: 1555-1561
Authors:  Zhang Y.;  Wang L.;  Zhou M.;  Zhou Z.;  Chen X.;  Chen T.;  Kwok H.;  Ivanyi C.;  Shaw C.
Favorite  |  View/Download:4/0  |  Submit date:2018/12/19
Antagonist  Bradykinin  Lizard  Mass Spectrometry  Molecular Cloning  Venom