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Rhodium(III)-Based Inhibitor of the JMJD3-H3K27me3 Interaction and Modulator of the Inflammatory Response Journal article
INORGANIC CHEMISTRY, 2018,Volume: 57,Issue: 22,Page: 14023-14026
作者:  Kang, Tian-Shu;  Ko, Chung-Nga;  Zhang, Jia-Tong;  Wu, Chun;  Wong, Chun-Yuen;  Ma, Dik-Lung;  Leung, Chung-Hang
收藏  |  浏览/下载:6/0  |  提交时间:2019/01/17
Selective Inhibition of Lysine-Specific Demethylase 5A (KDM5A) Using a Rhodium(III) Complex for Triple-Negative Breast Cancer Therapy Journal article
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2018,Volume: 57,Issue: 40,Page: 13091-13095
作者:  Yang, Guan-Jun;  Wang, Wanhe;  Mok, Simon Wing Fai;  Wu, Chun;  Law, Betty Yuen Kwan;  Miao, Xiang-Min;  Wu, Ke-Jia;  Zhong, Hai-Jing;  Wong, Chun-Yuen;  Wong, Vincent Kam Wai;  Ma, Dik-Lung;  Leung, Chung-Hang
收藏  |  浏览/下载:28/0  |  提交时间:2018/10/30
Drug Discovery  Epigenetics  Medicinal Chemistry  Triple-negative Breast Cancer  
Identification of a rhodium(III) complex as a Wee1 inhibitor against TP53-mutated triple-negative breast cancer cells Journal article
CHEMICAL COMMUNICATIONS, 2018,Volume: 54,Issue: 20,Page: 2463-2466
作者:  Yang, Guan-Jun;  Zhong, Hai-Jing;  Ko, Chung-Nga;  Wong, Suk-Yu;  Vellaisamy, Kasipandi;  Ye, Min;  Ma, Dik-Lung;  Leung, Chung-Hang
浏览  |  Adobe PDF(355Kb)  |  收藏  |  浏览/下载:203/24  |  提交时间:2018/10/30
Identification of a rhodium(III) complex as a Wee1 inhibitor against: TP53 -mutated triple-negative breast cancer cells Journal article
Chemical Communications, 2018,Volume: 54,Issue: 20,Page: 2463-2466
作者:  Yang G.-J.;  Zhong H.-J.;  Ko C.-N.;  Wong S.-Y.;  Vellaisamy K.;  Ye M.;  Ma D.-L.;  Leung C.-H.
收藏  |  浏览/下载:6/0  |  提交时间:2018/11/06
An anti-prostate cancer benzofuran-conjugated iridium(III) complex as a dual inhibitor of STAT3 and NF-kappa B Journal article
CANCER LETTERS, 2017,Volume: 396,Page: 76-84
作者:  Kang, Tian-Shu;  Wang, Wanhe;  Zhong, Hai-Jing;  Dong, Zhen-Zhen;  Huang, Qi;  Mok, Simon Wing Fai;  Leung, Chung-Hang;  Wong, Vincent Kam Wai;  Ma, Dik-Lung
收藏  |  浏览/下载:10/0  |  提交时间:2018/10/30
Benzofuran-conjugated iridium(III) complex  STAT3  NF-kappa B  Prostate cells  Dual inhibitors  
A Rhodium(III)-Based Inhibitor of Lysine-Specific Histone Demethylase 1 as an Epigenetic Modulator in Prostate Cancer Cells Journal article
JOURNAL OF MEDICINAL CHEMISTRY, 2017,Volume: 60,Issue: 6,Page: 2597-2603
作者:  Yang, Chao;  Wang, Wanhe;  Liang, Jia-Xin;  Li, Guodong;  Vellaisamy, Kasipandi;  Wong, Chun-Yuen;  Ma, Dik-Lung;  Leung, Chung-Hang
收藏  |  浏览/下载:13/0  |  提交时间:2018/10/30
A rhodium(III)-based inhibitor of autotaxin with antiproliferative activity Journal article
BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS, 2017,Volume: 1861,Issue: 2,Page: 256-263
作者:  Kang, Tian-Shu;  Wang, Wanhe;  Zhong, Hai-Jing;  Liang, Jia-Xin;  Ko, Chung-Nga;  Lu, Jin-Jian;  Chen, Xiu-Ping;  Ma, Dik-Lung;  Leung, Chung-Hang
收藏  |  浏览/下载:17/0  |  提交时间:2018/10/30
Rhodium Complex  Anticancer  Melanoma  Autotaxin  Inhibitor  
A Rhodium(III) Complex as an Inhibitor of Neural Precursor Cell Expressed, Developmentally Down-Regulated 8-Activating Enzyme with in Vivo Activity against Inflammatory Bowel Disease Journal article
JOURNAL OF MEDICINAL CHEMISTRY, 2017,Volume: 60,Issue: 1,Page: 497-503
作者:  Zhong, Hai-Jing;  Wang, Wanhe;  Kang, Tian-Shu;  Yan, Hui;  Yang, Yali;  Xu, Lipeng;  Wang, Yuqiang;  Ma, Dik-Lung;  Leung, Chung-Hang
浏览  |  Adobe PDF(3570Kb)  |  收藏  |  浏览/下载:139/7  |  提交时间:2018/10/30
An anti-prostate cancer benzofuran-conjugated iridium(III) complex as a dual inhibitor of STAT3 and NF-κB Journal article
Cancer Letters, 2017,Volume: 396,Page: 76
作者:  Kang T.-S.;  Wang W.;  Zhong H.-J.;  Dong Z.-Z.;  Huang Q.;  Mok S.W.F.;  Leung C.-H.;  Wong V.K.W.;  Ma D.-L.
收藏  |  浏览/下载:8/0  |  提交时间:2018/10/30
Benzofuran-conjugated Iridium(Iii) Complex  Dual Inhibitors  Nf-κb  Prostate Cells  Stat3  
Rhodium complexes as therapeutic agents Journal article
Dalton Transactions, 2016,Volume: 45,Issue: 7,Page: 2762-2771
作者:  Ma D.-L.;  Wang M.;  Mao Z.;  Yang C.;  Ng C.-T.;  Leung C.-H.
收藏  |  浏览/下载:0/0  |  提交时间:2018/11/06