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Berberine upregulates P-glycoprotein in human caco-2 cells and in an experimental model of colitis in the rat via activation of Nrf2-dependent mechanismss Journal article
Journal of Pharmacology and Experimental Therapeutics, 2018,Volume: 366,Issue: 2,Page: 332
Authors:  Jing W.;  Safarpour Y.;  Zhang T.;  Guo P.;  Chen G.;  Wu X.;  Fu Q.;  Wang Y.
Favorite  |  View/Download:12/0  |  Submit date:2018/10/31
C21-steroidal pregnane sapogenins and their derivatives as anti-inflammatory agents Journal article
Bioorganic and Medicinal Chemistry, 2017,Volume: 25,Issue: 13,Page: 3512
Authors:  Huang L.-J.;  Chen S.-R.;  Yuan C.-M.;  Gu W.;  Guo B.-J.;  Wang Y.-T.;  Wang Y.;  Hao X.-J.
Favorite  |  View/Download:7/0  |  Submit date:2018/10/31
Anti-inflammation  C21-steroidal Pregnane Steroids  Nf-κb  Tlr  Traf6  
Regulation of human pregnane X receptor and its target gene cytochrome P450 3A by praeruptorin a isolated from the herbal medicine peucedanum praeruptorum Journal article
Planta Medica, 2013,Volume: 79,Issue: 16,Page: 1509-1515
Authors:  Huang L.;  Bi H.-C.;  Li Y.-H.;  Zhang J.-Q.;  Kuang S.-Y.;  Zhang L.;  Wang Y.-T.;  Huang M.
Favorite  |  View/Download:8/0  |  Submit date:2018/11/06
Apiaceae  Cytochrome P450 3a  Herb-drug Interaction  Peucedanum Praeruptorum  Praeruptorin a  Pregnane x Receptor  
Up-regulatation of CYP3A expression through pregnent X receptor by praeruptorin D isolated from Peucedanum praeruptorum Dunn Journal article
Journal of Ethnopharmacology, 2013,Volume: 148,Issue: 2,Page: 596
Authors:  Huang L.;  Huang M.;  Li Y.-H.;  Li R.-M.;  Zeng Y.;  Kuang S.-Y.;  Zhang L.;  Wang Y.-T.;  Bi H.-C.
Favorite  |  View/Download:10/0  |  Submit date:2018/10/30
Praeruptorin d Pregnane x Receptor (Pxr) Cytochrome P450 3a Induction Herb-drug Interaction  
PXR-Mediated Upregulation of CYP3A Expression by Herb Compound Praeruptorin C from Peucedanum praeruptorum Dunn Journal article
EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE, 2013
Authors:  Huang, Ling;  Wu, Qian;  Li, Yu-Hua;  Wang, Yi-Tao;  Bi, Hui-Chang
Favorite  |  View/Download:4/0  |  Submit date:2018/11/01
SRC-3 is required for CAR-regulated hepatocyte proliferation and drug metabolism Journal article
JOURNAL OF HEPATOLOGY, 2012,Volume: 56,Issue: 1,Page: 210-217
Authors:  Tenghui Chen;  Qiang Chen;  Yixiang Xu;  Qiling Zhou;  Jingwei Zhu;  Hao Zhang;  Qiao Wu;  Jianming Xu;  Chundong Yu
Favorite  |  View/Download:3/0  |  Submit date:2019/01/22
Src-3  Car  Hepatocyte Proliferation  Drug Metabolism  
Regulation of human pregnane X receptor and its target gene cytochrome P450 3A4 by Chinese herbal compounds and a molecular docking study Journal article
XENOBIOTICA, 2011,Volume: 41,Issue: 4,Page: 259-280
Authors:  Liu, YH (Liu, Ya-He);  Mo, SL (Mo, Sui-Lin);  Bi, HC (Bi, Hui-Chang);  Hu, BF (Hu, Bing-Fang);  Li, CG (Li, Chun Guang);  Wang, YT (Wang, Yi-Tao);  Huang, L (Huang, Ling);  Huang, M (Huang, Min);  Duan, W (Duan, Wei);  Liu, JP (Liu, Jun-Ping);  Wei, MQ (Wei, Ming Qian);  Zhou, SF (Zhou, Shu-Feng)
Favorite  |  View/Download:5/0  |  Submit date:2018/11/01
Constitutive Androstane Receptor  Primary Human Hepatocytes  Corepressor Silencing-mediator  Hepatoma-cell Lines  Human Cyp3a4 Gene  Nuclear Receptor  Drug-metabolism  Transcriptional Activation  Xenobiotic Receptor  Interindividual Variability