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Combined transcriptomic and proteomic analysis reveals a diversity of venom-related and toxin-like peptides expressed in the mat anemone Zoanthus natalensis (Cnidaria, Hexacorallia) Journal article
ARCHIVES OF TOXICOLOGY, 2019,Volume: 93,Issue: 6,Page: 1745-1767
Authors:  Qiwen Liao;  Guiyi Gong;  Terence C. W. Poon;  Irene L. Ang;  Kate M. K. Lei;  Shirley Weng In Siu;  Clarence Tsun Ting Wong;  Gandhi Rádis-Baptista;  Simon Ming-Yuen Lee
Favorite | View/Download:230/0 | TC[WOS]:0 TC[Scopus]:0 | Submit date:2020/01/16
Cnidaria  Neuroprotection  Proteomic  Transcriptomic  Venom-derived Peptide  Zoantharian  
Neuroprotective Effects of BHDPC, a Novel Neuroprotectant, on Experimental Stroke by Modulating Microglia Polarization Journal article
ACS CHEMICAL NEUROSCIENCE, 2019,Volume: 10,Issue: 5,Page: 2434-2449
Authors:  Chuwen Li;  Yaqi Bian;  Yu Feng;  Fan Tang;  Liang Wang;  Maggie Pui Man Hoi;  Dan Ma;  Chao Zhao;  Simon Ming Yuen Lee
Favorite | View/Download:226/0 | TC[WOS]:4 TC[Scopus]:0 | Submit date:2020/01/16
Bhdpc  Ischemic Stroke  Microglia  Nf-κb  Creb  Pka  
Novel neurotoxic peptides from Protopalythoa variabilis virtually interact with voltage-gated sodium channel and display anti-epilepsy and neuroprotective activities in zebrafish Journal article
Archives of Toxicology, 2019,Volume: 93,Issue: 1,Page: 189-206
Authors:  Liao Q.;  Li S.;  Siu S.W.I.;  Morlighem J.-E.R.L.;  Wong C.T.T.;  Wang X.;  Radis-Baptista G.;  Lee S.M.-Y.
Favorite | View/Download:23/0 | TC[WOS]:2 TC[Scopus]:0 | Submit date:2019/04/04
Anti-epilepsy  Disulfide Bond  Neuroactive Peptides  Neuroprotection  Protein Docking  Voltage-gated Sodium Ion Channel Blocker  
Pinostrobin Exerts Neuroprotective Actions in Neurotoxin-Induced Parkinson's Disease Models through Nrf2 Induction Journal article
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2018,Volume: 66,Issue: 31,Page: 8307-8318
Authors:  Li, Chuwen;  Tang, Benqin;  Feng, Yu;  Tang, Fan;  Hoi, Maggie Pui-Man;  Su, Ziren;  Lee, Simon Ming-Yuen
Favorite | View/Download:22/0 | TC[WOS]:11 TC[Scopus]:0 | Submit date:2018/10/31
Pinostrobin  Parkinson's Disease  Neurotoxin  Nrf2  
BHDPC Is a Novel Neuroprotectant That Provides Anti-neuroinflammatory and Neuroprotective Effects by Inactivating NF-kappa B and Activating PKA/CREB Journal article
FRONTIERS IN PHARMACOLOGY, 2018,Volume: 9
Authors:  Li, Chuwen;  Chen, Tongkai;  Zhou, Hefeng;  Feng, Yu;  Hoi, Maggie P. M.;  Ma, Dan;  Zhao, Chao;  Zheng, Ying;  Lee, Simon M. Y.
Favorite | View/Download:39/0 | TC[WOS]:4 TC[Scopus]:0 | Submit date:2018/10/30
Bhdpc  Neuroinflammation  Microglia  Nf-kappa b  Creb  Pka  
BHDPC is a novel neuroprotectant that provides anti-neuroinflammatory and neuroprotective effects by inactivating NF-κB and activating PKA/CREB Journal article
Frontiers in Pharmacology, 2018,Volume: 9,Issue: JUN
Authors:  Li C.;  Chen T.;  Zhou H.;  Feng Y.;  Hoi M.P.M.;  Ma D.;  Zhao C.;  Zheng Y.;  Lee S.M.Y.
Favorite | View/Download:11/0 | TC[WOS]:4 TC[Scopus]:0 | Submit date:2018/11/06
BHDPC  CREB  Microglia  Neuroinflammation  NF-κB  PKA  
Inhibition of drug-induced seizure development in both zebrafish and mouse models by a synthetic nanoreceptor Journal article
Nanoscale, 2018,Volume: 10,Issue: 22,Page: 10333-10336
Authors:  Qiaoxian Huang;  Kit Ieng Kuok;  Xiangjun Zhang;  Ludan Yue;  Simon M. Y. Lee;  Jianxiang Zhang;  Ruibing Wang
Favorite | View/Download:12/0 | TC[WOS]:13 TC[Scopus]:0 | Submit date:2018/11/06
UPLC/Q-TOFMS-Based Metabolomics Approach to Reveal the Protective Role of Other Herbs in An-Gong-Niu-Huang Wan Against the Hepatorenal Toxicity of Cinnabar and Realgar Journal article
FRONTIERS IN PHARMACOLOGY, 2018,Volume: 9
Authors:  Xia, Fangbo;  Li, Ao;  Chai, Yushuang;  Xiao, Xiao;  Wan, Jianbo;  Li, Peng;  Wang, Yitao
View | Adobe PDF | Favorite | View/Download:549/29 | TC[WOS]:10 TC[Scopus]:0 | Submit date:2018/10/30
An-gong-niu-huang Wan  Cinnabar  Realgar  Metabonomics  Detoxification  Inflammation  
A novel ShK-like toxic peptide fromthe transcriptome of the cnidarian Palythoa caribaeorum displays neuroprotection and cardioprotection in zebrafish Journal article
Toxins, 2018,Volume: 10,Issue: 6
Authors:  Liao Q.;  Gong G.;  Siu S.W.I.;  Wong C.T.T.;  Yu H.;  Tse Y.C.;  Radis-Baptista G.;  Lee S.M.-Y.
Favorite | View/Download:15/0 | TC[WOS]:4 TC[Scopus]:0 | Submit date:2018/11/06
Animal toxins  Calcium-activated K+ ion channel  Dynamics simulation  ShK-like peptide  Voltage-gated K+ ion channel  Zoantharian  
Enriched Brain Omega-3 Polyunsaturated Fatty Acids Confer Neuroprotection against Microinfarction Journal article
EBIOMEDICINE, 2018,Volume: 32,Page: 50-61
Authors:  Luo, Chuanming;  Ren, Huixia;  Yao, Xiaoli;  Shi, Zhe;  Liang, Fengyin;  Kang, Jing X.;  Wan, Jian-bo;  Pei, Zhong;  Su, Kuan-Pin;  Su, Huanxing
Favorite | View/Download:22/0 | TC[WOS]:9 TC[Scopus]:0 | Submit date:2018/10/30
Fish Oil  Cognitive Decline  Vascular Dementia  Neuropsychiatric Disorders