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| The emerging role of KDM5A in human cancer Journal article
Journal of Hematology and Oncology, 2021,Volume: 14,Issue: 1
Authors: Yang，Guan Jun; Zhu，Ming Hui; Lu，Xin Jiang; Liu，Yan Jun; Lu，Jian Fei; Leung，Chung Hang; Ma，Dik Lung; Chen，Jiong
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Cancer Drug resistance Histone methylation Jumonji C domain KDM5A Targeted therapy |
| Simultaneous blocking of the pan-RAF and S100B pathways as a synergistic therapeutic strategy against malignant melanoma Journal article
Journal of Cellular and Molecular Medicine, 2021,Volume: 25,Issue: 4,Page: 1972-1981
Authors: Wu，Ke Jia; Ho，Shih Hsin; Wu，Chun; Wang，Hui Min D.; Ma，Dik Lung; Leung，Chung Hang
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drug discovery malignant melanoma pan-RAF S100B-p53 interaction synergistic |
| Time-resolved luminescent high-throughput screening platform for lysosomotropic compounds in living cells Journal article
ACS Sensors, 2021
Authors: Wu，Ke Jia; Wu，Chun; Chen，Feng; Cheng，Sha Sha; Ma，Dik Lung; Leung，Chung Hang
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High-throughput screening Iridium-based pH probe Lysosomotropic compounds Mitoxantrone Time-resolved emission spectroscopy |
| Licochalcone A inhibits interferon-gamma-induced programmed death-ligand 1 in lung cancer cells Journal article
Phytomedicine, 2021,Volume: 80
Authors: Yuan，Luo Wei; Jiang，Xiao Ming; Xu，Yu Lian; Huang，Mu Yang; Chen，Yu Chi; Yu，Wei Bang; Su，Min Xia; Ye，Zi Han; Chen，Xiuping ; Wang，Yitao; Lu，Jin Jian
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IFN-γ Licochalcone A Natural products PD-L1 Protein synthesis inhibitor ROS |
| A 7-methoxybicoumarin derivative selectively inhibits BRD4 BD2 for anti-melanoma therapy Journal article
International Journal of Biological Macromolecules, 2020,Volume: 164,Page: 3204-3220
Authors: Yang，Guan Jun; Wang，Wanhe; Lei，Pui Man; Leung，Chung Hang; Ma，Dik Lung
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BRD4 Bromodomain domain Cell metastasis and invasion Histone acetylation Melanoma Protein–protein interaction Virtual screening |
| Structure-guided discovery of a luminescent theranostic toolkit for living cancer cells and the imaging behavior effect Journal article
Chemical Science, 2020,Volume: 11,Issue: 42,Page: 11404-11412
Authors: Wu，Chun; Wu，Ke Jia; Liu，Jin Biao; Wang，Wanhe; Leung，Chung Hang; Ma，Dik Lung
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| Peptide-Conjugated Long-Lived Theranostic Imaging for Targeting GRPr in Cancer and Immune Cells Journal article
Angewandte Chemie - International Edition, 2020,Volume: 59,Issue: 41,Page: 17897-17902
Authors: Wang，Wanhe; Wu，Ke Jia; Vellaisamy，Kasipandi; Leung，Chung Hang; Ma，Dik Lung
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gastrin-releasing peptide receptor (GRPr) peptide-conjugated transition-metal complexes theranostic agents time-resolved emission spectroscopy |
| Natural alkaloid 8-oxo-epiberberine inhibited TGF-β1-triggred epithelial-mesenchymal transition by interfering Smad3 Journal article
Toxicology and Applied Pharmacology, 2020,Volume: 404
Authors: Liu，Xin; Zhang，Yiying; ZHOU，Guang Ju; Hou，Ying; Kong，Qi; Lu，Jin Jian; Zhang，Qingwen; Chen，Xiuping
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8-Oxo-epiberberine Epithelial-mesenchymal transition Metastasis TGF-β1 |
| Interfering with S100B–effector protein interactions for cancer therapy Journal article
Drug Discovery Today, 2020,Volume: 25,Issue: 9,Page: 1754-1761
Authors: Wu，Ke Jia; Wang，Wanhe; Wang，Hui Min David; Leung，Chung Hang; Ma，Dik Lung
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| Nagilactone E increases PD-L1 expression through activation of c-Jun in lung cancer cells Journal article
Chinese Journal of Natural Medicines, 2020,Volume: 18,Issue: 7,Page: 517-525
Authors: CHEN，Yu Chi; HUANG，Mu Yang; ZHANG，Le Le; FENG，Zhe Ling; JIANG，Xiao Ming; YUAN，Luo Wei; HUANG，Run Yue; LIU，Bo; YU，Hua; WANG，Yi Tao; CHEN，Xiu Ping; LIN，Li Gen; LU，Jin Jian
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c-Jun JNK Lung cancer Nagilactone E Programmed death ligand 1 |
