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Serum amyloid A promotes LPS clearance and suppresses LPS-induced inflammation and tissue injury Journal article
EMBO REPORTS, 2018,Volume: 19,Issue: 10
Authors:  Cheng, Ni;  Liang, Yurong;  Du, Xiaoping;  Ye, Richard D.
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acute-phase response  inflammation  innate immunity  lipopolysaccharide  serum amyloid A  
Andrographolide derivative as STAT3 inhibitor that protects acute liver damage in mice Journal article
BIOORGANIC & MEDICINAL CHEMISTRY, 2018,Volume: 26,Issue: 18,Page: 5053-5061
Authors:  Chen, Shao-Ru;  Li, Feng;  Ding, Mo-Yu;  Wang, Decai;  Zhao, Qi;  Wang, Yitao;  Zhou, Guo-Chun;  Wang, Ying
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Andrographolide  Stat3 Inhibitor  Acute Liver Damage  Inflammation  
MK2 mediates macrophage activation and acute lung injury by regulating let-7e miRNA Journal article
AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY, 2018,Volume: 315,Issue: 3,Page: L371-L381
Authors:  Wu, Yaxian;  He, Huiqiong;  Ding, Yunhe;  Liu, Sirui;  Zhang, Depeng;  Wang, Jun;  Jiang, Hongchao;  Zhang, Dan;  Sun, Lei;  Ye, Richard D.;  Qian, Feng
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acute lung injury  let-7e  lipopolysaccharides  macrophage  MAPK-activated protein kinase 2  miRNA  MK2  
Polysaccharide PRM3 from Rhynchosia minima root enhances immune function through TLR4-NF-κB pathway Journal article
Biochimica et Biophysica Acta - General Subjects, 2018,Volume: 1862,Issue: 8,Page: 1751-1759
Authors:  Jia X.;  Liang Y.;  Zhang C.;  Wang K.;  Tu Y.;  Chen M.;  Li P.;  Wan J.-B.;  He C.
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Immunomodulation  NF-κB  Polysaccharide  Rhynchosia minima root  Toll-like receptor 4  
Polysaccharide PRM3 from Rhynchosia minima root enhances immune function through TLR4-NF-kappa B pathway Journal article
BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS, 2018,Volume: 1862,Issue: 8,Page: 1751-1759
Authors:  Jia, Xuejing;  Liang, Yeer;  Zhang, Chao;  Wang, Kai;  Tu, Yanbei;  Chen, Meiwan;  Li, Peng;  Wan, Jian-Bo;  He, Chengwei
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Rhynchosia minima root  Polysaccharide  Immunomodulation  Toll-like receptor 4  NF-kappa B  
Interference of Quercetin on Astragalus Polysaccharide-Induced Macrophage Activation Journal article
MOLECULES, 2018,Volume: 23,Issue: 7
Authors:  Li, Zhi-Peng;  Liu, Hong-Bing;  Zhang, Quan-Wei;  Li, Li-Feng;  Bao, Wan-Rong;  Ma, Dik-Lung;  Leung, Chung-Hang;  Bian, Zhao-Xiang;  Lu, Ai-Ping;  Han, Quan-Bin
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astragalus polysaccharide  quercetin  cytokines  macrophage  foods  
Elevated expression of serum amyloid A 3 protects colon epithelium against acute injury through TLR2-dependent induction of neutrophil IL-22 expression in a mouse model of colitis Journal article
Frontiers in Immunology, 2018,Volume: 9,Issue: JUN
Authors:  Zhang G.;  Liu J.;  Wu L.;  Fan Y.;  Sun L.;  Qian F.;  Chen D.;  Ye R.D.
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Colitis  Cytokines  Inflammation  Innate immunity  Neutrophils  Serum amyloid A  
Elevated Expression of Serum Amyloid A 3 Protects Colon Epithelium Against Acute Injury Through TLR2-Dependent Induction of Neutrophil IL-22 Expression in a Mouse Model of Colitis Journal article
FRONTIERS IN IMMUNOLOGY, 2018,Volume: 9
Authors:  Zhang, Gufang;  Liu, Jin;  Wu, Lehao;  Fang, Yu;  Sun, Lei;  Qian, Feng;  Chen, Daijie;  Ye, Richard D.
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serum amyloid A  inflammation  innate immunity  cytokines  colitis  neutrophils  
Discovery and preliminary SAR of 14-aryloxy-andrographolide derivatives as antibacterial agents with immunosuppressant activity Journal article
RSC ADVANCES, 2018,Volume: 8,Issue: 17,Page: 9440-9456
Authors:  Li, Feng;  Li, Xiao-Min;  Sheng, Dekuan;  Chen, Shao-Ru;  Nie, Xin;  Liu, Zhuyun;  Wang, Decai;  Zhao, Qi;  Wang, Yitao;  Wang, Ying;  Zhou, Guo-Chun
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4-Aroyl-3-hydroxy-5-phenyl-1H-pyrrol-2(5H)-ones as N-formyl peptide receptor 1 (FPR1) antagonists Journal article
BIOCHEMICAL PHARMACOLOGY, 2017,Volume: 142,Page: 120-132
Authors:  Kirpotina, Liliya N.;  Schepetkin, Igor A.;  Khlebnikov, Andrei I.;  Ruban, Olga I.;  Ge, Yunjun;  Ye, Richard D.;  Kominsky, Douglas J.;  Quinn, Mark T.
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Antagonist Formyl peptide receptor  1H-pyrrol-2(5H)-one  Neutrophil  Molecular modeling