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Generation of Human Fatty Livers Using Custom-Engineered Induced Pluripotent Stem Cells with Modifiable SIRT1 Metabolism Journal article
Cell Metabolism, 2019,Volume: 30,Issue: 2,Page: 385-401.e9
Authors:  Collin de l'Hortet,Alexandra;  Takeishi,Kazuki;  Guzman-Lepe,J.;  Morita,Kazutoyo;  Achreja,Abhinav;  Popovic,Branimir;  Wang,Yang;  Handa,Kan;  Mittal,Anjali;  Meurs,Noah;  Zhu,Z.;  Weinberg,F.;  Salomon,Michael;  Fox,I. J.;  Deng,Chu Xia;  Nagrath,Deepak;  Soto-Gutierrez,Alejandro
Favorite | View/Download:72/0 | TC[WOS]:10 TC[Scopus]:11 | Submit date:2020/09/16
cellular engineering  hepatic differentiation  human fatty liver  human iPSCs  liver metabolism  NAFLD  NASH  SIRT1  
Andrographolide derivative as STAT3 inhibitor that protects acute liver damage in mice Journal article
BIOORGANIC & MEDICINAL CHEMISTRY, 2018,Volume: 26,Issue: 18,Page: 5053-5061
Authors:  Chen, Shao-Ru;  Li, Feng;  Ding, Mo-Yu;  Wang, Decai;  Zhao, Qi;  Wang, Yitao;  Zhou, Guo-Chun;  Wang, Ying
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Andrographolide  Stat3 Inhibitor  Acute Liver Damage  Inflammation  
Water soluble fraction from ethanolic extract of Clausena lansium seeds alleviates obesity and insulin resistance, and changes the composition of gut microbiota in high-fat diet-fed mice Journal article
JOURNAL OF FUNCTIONAL FOODS, 2018,Volume: 47,Page: 192-199
Authors:  Shen, Shengnan;  Liao, Qiwen;  Huang, Li;  Li, Dan;  Zhang, Qingwen;  Wang, Yitao;  Lee, Simon Ming-Yuen;  Lin, Ligen
View | Adobe PDF | Favorite | View/Download:745/40 | TC[WOS]:3 TC[Scopus]:0 | Submit date:2018/10/30
Clausena Lansium  Fat Mass Gain  Insulin Sensitivity  Gut Microbiota  Wampee  
Downregulation of Cyclin B1 mediates nagilactone E-induced G2 phase cell cycle arrest in non-small cell lung cancer cells Journal article
EUROPEAN JOURNAL OF PHARMACOLOGY, 2018,Volume: 830,Page: 17-25
Authors:  Zhang, Le-Le;  Feng, Zhe-Ling;  Su, Min-Xia;  Jiang, Xiao-Ming;  Chen, Xiuping;  Wang, Yitao;  Li, Ao;  Lin, Li-Gen;  Lu, Jin-Jian
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Nagilactone e  Non-small Cell Lung Cancer  Cyclin B1  Cell Cycle  Apoptosis  
UPLC/Q-TOFMS-Based Metabolomics Approach to Reveal the Protective Role of Other Herbs in An-Gong-Niu-Huang Wan Against the Hepatorenal Toxicity of Cinnabar and Realgar Journal article
FRONTIERS IN PHARMACOLOGY, 2018,Volume: 9
Authors:  Xia, Fangbo;  Li, Ao;  Chai, Yushuang;  Xiao, Xiao;  Wan, Jianbo;  Li, Peng;  Wang, Yitao
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An-gong-niu-huang Wan  Cinnabar  Realgar  Metabonomics  Detoxification  Inflammation  
Pinocembrin from Penthorum chinense Pursh suppresses hepatic stellate cells activation through a unified SIRT3-TGF-beta-Smad signaling pathway Journal article
TOXICOLOGY AND APPLIED PHARMACOLOGY, 2018,Volume: 341,Page: 38-50
Authors:  Zhou, Fayang;  Wang, Anqi;  Li, Dan;  Wang, Yitao;  Lin, Ligen
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Liver Fibrosis  Hepatic Stellate Cells  Penthorum Chinense Pursh  Pinocembrin  Sma- And Mad-related Proteins  Silent Mating Type Information Regulation 2 Homolog 3  
gamma-Mangostin, a xanthone from mangosteen, attenuates oxidative injury in liver via NRF2 and SIRT1 induction Journal article
JOURNAL OF FUNCTIONAL FOODS, 2018,Volume: 40,Page: 544-553
Authors:  Wang, Anqi;  Li, Dan;  Wang, Shengpeng;  Zhou, Fayang;  Li, Peng;  Wang, Yitao;  Lin, Ligen
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Gamma-mangostin  Mangosteen  Liver Oxidative Injury  Nrf2  Sirt1  Pgc-1 Alpha  
Cleavable Multifunctional Targeting Mixed Micelles with Sequential pH-Triggered TAT Peptide Activation for Improved Antihepatocellular Carcinoma Efficacy Journal article
MOLECULAR PHARMACEUTICS, 2017,Volume: 14,Issue: 11,Page: 3644-3659
Authors:  Zhang, Jinming;  Zheng, Yifeng;  Xie, Xi;  Wang, Lan;  Su, Ziren;  Wang, Yitao;  Leong, Kam W.;  Chen, Meiwan
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Tumor-targeting  Glycyrrhetinic Acid  Ph-sensitive  Tat Exposure  Mixed Micelles  
Mori Cortex regulates P-glycoprotein in Caco-2 cells and colons from rats with experimental colitis via direct and gut microbiota-mediated mechanisms Journal article
RSC ADVANCES, 2017,Volume: 7,Issue: 5,Page: 2594-2605
Authors:  Jing, Wanghui;  Gao, Xuejiao;  Han, Beilei;  Wei, Bin;  Hu, Nan;  Li, Sai;  Yan, Ru;  Wang, Yitao
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SIRT1 disruption in human fetal hepatocytes leads to increased accumulation of glucose and lipids Journal article
PLoS ONE, 2016,Volume: 11,Issue: 2
Authors:  Tobita T.;  Guzman-Lepe J.;  Takeishi K.;  Nakao T.;  Wang Y.;  Meng F.;  Deng C.-X.;  De L'Hortet A.C.;  Soto-Gutierrez A.
Favorite | View/Download:10/0 | TC[WOS]:21 TC[Scopus]:0 | Submit date:2018/12/13