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Optimizing CRISPR/Cas9 technology for precise correction of the Fgfr3-Gly374Arg mutation in achondroplasia in mice Journal article
The Journal of Biological Chemistry, 2018
Authors:  Kai Miao;  Xin Zhang;  Sek Man Su;  Jianming Zeng;  Zebin Huang;  Un In Chan;  Xiaoling Xu;  Chu-Xia Deng
Favorite  |  View/Download:15/0  |  Submit date:2018/12/17
Fgfr3  Crispr/cas9  Protein  Targeted Correction  Off-target  Achondroplasia  Dwarfism  Genome Editing  Gene Therapy  
The chromatin accessibility landscape of primary human cancers Journal article
Science, 2018,Volume: 362,Issue: 6413
Authors:  Corces M.R.;  Granja J.M.;  Shams S.;  Louie B.H.;  Seoane J.A.;  Zhou W.;  Silva T.C.;  Groeneveld C.;  Wong C.K.;  Cho S.W.;  Satpathy A.T.;  Mumbach M.R.;  Hoadley K.A.;  Robertson A.G.;  Sheffield N.C.;  Felau I.;  Castro M.A.A.;  Berman B.P.;  Staudt L.M.;  Zenklusen J.C.;  Laird P.W.;  Curtis C.;  Greenleaf W.J.;  Chang H.Y.
Favorite  |  View/Download:4/0  |  Submit date:2019/01/16
Cyclin B1 stability is increased by interaction with BRCA1, and its overexpression suppresses the progression of BRCA1-associated mammary tumors Journal article
Experimental and Molecular Medicine, 2018,Volume: 50,Page: 136
Authors:  Choi, Eun Kyung;  Lim, Jeong-A;  Kim, Jong Kwang;  Jang, Moon Sun;  Kim, Sun Eui;  Baek, Hye Jung;  Park, Eun Jung;  Kim, Tae Hyun;  Deng, Chu-Xia;  Wang, Rui-Hong;  Kim, Sang Soo
Favorite  |  View/Download:13/0  |  Submit date:2018/10/30
Vascular endothelial growth factor gene transfer therapy for coronary artery disease: A systematic review and meta-analysis Journal article
CARDIOVASCULAR THERAPEUTICS, 2018,Volume: 36,Issue: 5
Authors:  Yuan, Rong;  Xin, Qiqi;  Shi, Weili;  Liu, Wei;  Lee, Simon-M.;  Hoi, Puiman;  Li, Lin;  Zhao, Jun;  Cong, Weihong;  Chen, Keji
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Angina Pectoris  Angiogenesis Inducing Agents  Coronary Artery Disease  Genetic Therapy  Myocardial Ischemia  Vascular Endothelial Growth Factor  
Andrographolide derivative as STAT3 inhibitor that protects acute liver damage in mice Journal article
BIOORGANIC & MEDICINAL CHEMISTRY, 2018,Volume: 26,Issue: 18,Page: 5053-5061
Authors:  Chen, Shao-Ru;  Li, Feng;  Ding, Mo-Yu;  Wang, Decai;  Zhao, Qi;  Wang, Yitao;  Zhou, Guo-Chun;  Wang, Ying
View  |  Adobe PDF(2009Kb)  |  Favorite  |  View/Download:305/44  |  Submit date:2018/10/30
Andrographolide  Stat3 Inhibitor  Acute Liver Damage  Inflammation  
Toosendanin, a natural product, inhibited TGF-1-induced epithelial-mesenchymal transition through ERK/Snail pathway Journal article
PHYTOTHERAPY RESEARCH, 2018,Volume: 32,Issue: 10,Page: 2009-2020
Authors:  Luo, Weiwei;  Liu, Xin;  Sun, Wen;  Lu, Jin-Jian;  Wang, Yitao;  Chen, Xiuping
View  |  Adobe PDF(2621Kb)  |  Favorite  |  View/Download:242/23  |  Submit date:2018/10/30
Emt  Erk1/2  Snail  Lung Cancer  Toosendanin  
Neural stem cells for disease modeling and evaluation of therapeutics for Tay-Sachs disease Journal article
ORPHANET JOURNAL OF RARE DISEASES, 2018,Volume: 13
Authors:  Vu, Mylinh;  Li, Rong;  Baskfield, Amanda;  Lu, Billy;  Farkhondeh, Atena;  Gorshkov, Kirill;  Motabar, Omid;  Beers, Jeanette;  Chen, Guokai;  Zou, Jizhong;  Espejo-Mojica, Angela J.;  Rodriguez-Lopez, Alexander;  Almeciga-Diaz, Carlos J.;  Barrera, Luis A.;  Jiang, Xuntian;  Ory, Daniel S.;  Marugan, Juan J.;  Zheng, Wei
Favorite  |  View/Download:17/0  |  Submit date:2018/10/30
Tay-Sachs disease  Induced pluripotent stem cells  Neural stem cells  Cyclodextrin  HP beta CD  delta-tocopherol  Enzyme replacement therapy  Hexosaminidase A  GM2 gangliosidosis  High throughput screening  Drug discovery  
MK2 mediates macrophage activation and acute lung injury by regulating let-7e miRNA Journal article
AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY, 2018,Volume: 315,Issue: 3,Page: L371-L381
Authors:  Wu, Yaxian;  He, Huiqiong;  Ding, Yunhe;  Liu, Sirui;  Zhang, Depeng;  Wang, Jun;  Jiang, Hongchao;  Zhang, Dan;  Sun, Lei;  Ye, Richard D.;  Qian, Feng
View  |  Adobe PDF(2092Kb)  |  Favorite  |  View/Download:109/7  |  Submit date:2018/10/30
acute lung injury  let-7e  lipopolysaccharides  macrophage  MAPK-activated protein kinase 2  miRNA  MK2  
Universal corneal epithelial-like cells derived from human embryonic stem cells for cellularization of a corneal scaffold Journal article
Translational Vision Science and Technology, 2018,Volume: 7,Issue: 5
Authors:  Yang J.;  Park J.W.;  Zheng D.;  Xu R.-H.
Favorite  |  View/Download:7/0  |  Submit date:2018/12/20
B2m Knockout  Corneal Epithelial Cells  Decellularized Cornea  Differentiation  Human Embryonic Stem Cells  Immunogenicity  
cAMP Response Element-Binding Protein (CREB): A Possible Signaling Molecule Link in the Pathophysiology of Schizophrenia Journal article
FRONTIERS IN MOLECULAR NEUROSCIENCE, 2018,Volume: 11
Authors:  Wang, Haitao;  Xu, Jiangping;  Lazarovici, Philip;  Quirion, Remi;  Zheng, Wenhua
Favorite  |  View/Download:5/0  |  Submit date:2018/10/30
CREB  schizophrenia  neurotransmitter  neurodevelopment  dopamine