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Cyclin B1 stability is increased by interaction with BRCA1, and its overexpression suppresses the progression of BRCA1-associated mammary tumors Journal article
Experimental and Molecular Medicine, 2018,Volume: 50,Page: 136
Authors:  Choi, Eun Kyung;  Lim, Jeong-A;  Kim, Jong Kwang;  Jang, Moon Sun;  Kim, Sun Eui;  Baek, Hye Jung;  Park, Eun Jung;  Kim, Tae Hyun;  Deng, Chu-Xia;  Wang, Rui-Hong;  Kim, Sang Soo
Favorite  |  View/Download:12/0  |  Submit date:2018/10/30
Chaetominine induces cell cycle arrest in human leukemia K562 and colon cancer SW1116 cells Journal article
ONCOLOGY LETTERS, 2018,Volume: 16,Issue: 4,Page: 4671-4678
Authors:  Yao, Jingyun;  Xiao, Jianbo;  Wei, Xing;  Lu, Yanhua
Favorite  |  View/Download:14/0  |  Submit date:2018/10/30
cell cycle arrest  cyclin  cyclin-dependent kinase  chaetominine  K562 cells  SW1116 cells  
Triggering of cancer cell cycle arrest by a novel scorpion venom-derived peptide-Gonearrestide Journal article
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE, 2018,Volume: 22,Issue: 9,Page: 4460-4473
Authors:  Li, Bin;  Lyu, Peng;  Xi, Xinping;  Ge, Lilin;  Mahadevappa, Ravikiran;  Shaw, Chris;  Kwok, Hang Fai
Favorite  |  View/Download:9/0  |  Submit date:2018/10/30
Anticancer Mechanism  Binding Sites  Ms  Ms Proteome  Ngs Transcriptome  Signalling Pathways  Venom Library  
Downregulation of Cyclin B1 mediates nagilactone E-induced G2 phase cell cycle arrest in non-small cell lung cancer cells Journal article
EUROPEAN JOURNAL OF PHARMACOLOGY, 2018,Volume: 830,Page: 17-25
Authors:  Zhang, Le-Le;  Feng, Zhe-Ling;  Su, Min-Xia;  Jiang, Xiao-Ming;  Chen, Xiuping;  Wang, Yitao;  Li, Ao;  Lin, Li-Gen;  Lu, Jin-Jian
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Nagilactone e  Non-small Cell Lung Cancer  Cyclin B1  Cell Cycle  Apoptosis  
Physalin B induces cell cycle arrest and triggers apoptosis in breast cancer cells through modulating p53-dependent apoptotic pathway Journal article
BIOMEDICINE & PHARMACOTHERAPY, 2018,Volume: 101,Page: 334-341
Authors:  Wang, Anqi;  Wang, Shengpeng;  Zhou, Fayang;  Li, Peng;  Wang, Yitao;  Gan, Lishe;  Lin, Ligen
View  |  Adobe PDF(1614Kb)  |  Favorite  |  View/Download:105/11  |  Submit date:2018/10/30
Physalin b  Breast Cancer  Cell Cycle  Apoptosis  P53  Akt  
Flavopiridol inhibits TGF-b-stimulated biglycan synthesis by blocking linker region phosphorylation and nuclear translocation of Smad2 Journal article
Journal of Pharmacology and Experimental Therapeutics, 2018,Volume: 365,Issue: 1,Page: 156-164
Authors:  Rostam M.A.;  Shajimoon A.;  Kamato D.;  Mitra P.;  Piva T.J.;  Getachew R.;  Cao Y.;  Zheng W.;  Osman N.;  Little P.J.
Favorite  |  View/Download:1/0  |  Submit date:2018/12/21
Flavopiridol Inhibits TGF-beta-Stimulated Biglycan Synthesis by Blocking Linker Region Phosphorylation and Nuclear Translocation of Smad2 Journal article
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, 2018,Volume: 365,Issue: 1,Page: 156-164
Authors:  Rostam, Muhamad A.;  Shajimoon, Aravindra;  Kamato, Danielle;  Mitra, Partha;  Piva, Terrence J.;  Getachew, Robel;  Cao, Yingnan;  Zheng, Wenhua;  Osman, Narin;  Little, Peter J.
Favorite  |  View/Download:8/0  |  Submit date:2018/10/30
Forkhead box protein O3 suppresses uveal melanoma development by increasing the expression of Bcl-2-like protein 11 and cyclin-dependent kinase inhibitor 1B Journal article
MOLECULAR MEDICINE REPORTS, 2018,Volume: 17,Issue: 2,Page: 3109-3114
Authors:  Yan, Fengxia;  Liao, Rifang;  Lin, Shaofen;  Deng, Xianguo;  Little, Peter J.;  Zheng, Wenhua
Favorite  |  View/Download:12/0  |  Submit date:2018/10/30
uveal melanoma  forkhead box protein O3  cell cycle phase  uveal melanoma cells  
Substantial protection against MPTP-associated Parkinson's neurotoxicity in vitro and in vivo by anti-cancer agent SU4312 via activation of MEF2D and inhibition of MAO-B Journal article
NEUROPHARMACOLOGY, 2017,Volume: 126,Page: 12-24
Authors:  Guo, Baojian;  Hu, Shengquan;  Zheng, Chengyou;  Wang, Hongyu;  Luo, Fangcheng;  Li, Haitao;  Cui, Wei;  Yang, Xifei;  Cui, Guozhen;  Mak, Shinghung;  Choi, Tony Chung-Lit;  Ma, Edmond Dik-Lung;  Wang, Yuqiang;  Lee, Simon Ming Yuen;  Zhang, Zaijun;  Han, Yifan
View  |  Adobe PDF(2766Kb)  |  Favorite  |  View/Download:100/4  |  Submit date:2018/10/31
Parkinson's disease  SU4312  Neuroprotection  Myocyte enhancer factor 2D  Monoamine oxidase-B  
Up-regulation of CDK16 by multiple mechanisms in hepatocellular carcinoma promotes tumor progression Journal article
JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH, 2017,Volume: 36
Authors:  Wang, Yitao;  Qin, Xian;  Guo, Tao;  Liu, Pengpeng;  Wu, Ping;  Liu, Zhisu
Favorite  |  View/Download:2/0  |  Submit date:2018/11/01
Hepatocellular carcinoma (HCC)  Cyclin dependent Kinase 16 (CDK16)  Epithelial mesenchymal transition (EMT)  E2F1 transcription factor  miR-125b-5p