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NOTCH1 activation compensates BRCA1 deficiency and promotes triple-negative breast cancer formation Journal article
Nature Communications, 2020,Volume: 11,Issue: 1
Authors:  Miao,Kai;  Lei,Josh Haipeng;  Valecha,Monica Vishnu;  Zhang,Aiping;  Xu,Jun;  Wang,Lijian;  Lyu,Xueying;  Chen,Si;  Miao,Zhengqiang;  Zhang,Xin;  Su,Sek Man;  Shao,Fangyuan;  Rajendran,Barani Kumar;  Bao,Jiaolin;  Zeng,Jianming;  Sun,Heng;  Chen,Ping;  Tan,Kaeling;  Chen,Qiang;  Wong,Koon Ho;  Xu,Xiaoling;  Deng,Chu Xia
Favorite | View/Download:258/0 | TC[WOS]:0 TC[Scopus]:1 | Submit date:2020/09/16
Rmrp Mutation Disrupts Chondrogenesis and Bone Ossification in Zebrafish Model of Cartilage-Hair Hypoplasia via Enhanced Wnt/β-Catenin Signaling Journal article
Journal of Bone and Mineral Research, 2019,Volume: 34,Issue: 11,Page: 2101-2116
Authors:  Sun,Xianding;  Zhang,Ruobin;  Liu,Mi;  Chen,Hangang;  Chen,Liang;  Luo,Fengtao;  Zhang,Dali;  Huang,Junlan;  Li,Fangfang;  Ni,Zhenhong;  Qi,Huabing;  Su,Nan;  Jin,Min;  Yang,Jing;  Tan,Qiaoyan;  Du,Xiaolan;  Chen,Bo;  Huang,Haiyang;  Chen,Shuai;  Yin,Liangjun;  Xu,Xiaoling;  Deng,Chuxia;  Luo,Lingfei;  Xie,Yangli;  Chen,Lin
Favorite | View/Download:75/0 | TC[WOS]:2 TC[Scopus]:3 | Submit date:2020/09/16
CARTILAGE-HAIR HYPOPLASIA  RMRP  SKELETAL DEVELOPMENT  WNT/Β-CATENIN  ZEBRAFISH  
Elevated Exogenous Pyruvate Potentiates Mesodermal Differentiation through Metabolic Modulation and AMPK/mTOR Pathway in Human Embryonic Stem Cells Journal article
STEM CELL REPORTS, 2019,Volume: 13,Issue: 2,Page: 338-351
Authors:  Chengcheng Song;  Faxiang Xu;  Zhili Ren;  Yumeng Zhang;  Ya Meng;  Yiqi Yang;  Shreyas Lingadahalli;  Edwin Cheung;  Gang Li;  Weiwei Liu;  Jianbo Wan;  Yang Zhao;  Guokai Chen
Favorite | View/Download:23/0 | TC[WOS]:1 TC[Scopus]:3 | Submit date:2020/04/22
Hescs  Pyruvate  Bmp4  Glycolysis  Tca Cycle  Ampk  Wnt  Metabolism  Mesoderm  Differentiation  
Development of functional dendrisomes based on a single molecule of polyesterbenzylether dendrimer and their application in cancer stem cell therapy Journal article
NPG ASIA MATERIALS, 2019,Volume: 11
Authors:  Li-Min Mu;  Lei Liu;  Rui Liu;  Jia-Lun Duan;  Shuang Ma;  Xue-Qi Li;  Yi-Nuo Cui;  Zhan-Bo Su;  Xiao Zhang;  Jian-Xing Hu;  Ying Xie;  Ying Zheng;  Wan-Liang Lu
Favorite | View/Download:17/0 | TC[WOS]:0 TC[Scopus]:1 | Submit date:2020/04/08
Combined use of arginase and dichloroacetate exhibits anti-proliferative effects in triple negative breast cancer cells Journal article
JOURNAL OF PHARMACY AND PHARMACOLOGY, 2019,Volume: 71,Issue: 3,Page: 306-315
Authors:  Angela Verma;  Yau-Min Lam;  Yun-Chung Leung;  Xiaohui Hu;  Xin Chen;  Edwin Cheung;  Kin Yip Tam
Favorite | View/Download:25/0 | TC[WOS]:3 TC[Scopus]:5 | Submit date:2020/05/21
Bacillus Caldovelox Arginase  Breast Cancer  Dichloroacetate  Drug Combination  Pegyated Human Arginase  
CBX6 is negatively regulated by EZH2 and plays a potential tumor suppressor role in breast cancer Journal article
SCIENTIFIC REPORTS, 2019,Volume: 9
Authors:  Houliang Deng;  Xiaowen Guan;  Longcai Gong;  Jianming Zeng;  Hongjie Zhang;  Mike Y. Chen;  Gang Li
Favorite | View/Download:7/0 | TC[WOS]:1 TC[Scopus]:5 | Submit date:2020/06/22
Genetic Analysis of Candida auris Implicates Hsp90 in Morphogenesis and Azole Tolerance and Cdr1 in Azole Resistance Journal article
MBIO, 2019,Volume: 10,Issue: 1
Authors:  Sang Hu Kim;  Kali R. Iyer;  Lakhansing Pardeshi;  José F. Muñoz;  Nicole Robbins;  Christina A. Cuomo;  Koon Ho Wong;  Leah E. Cowen
Favorite | View/Download:14/0 | TC[WOS]:13 TC[Scopus]:25 | Submit date:2020/06/12
Antifungal Drug Resistance  Candida Albicans  Candida Auris  Cdr1  Developmental Program  Emerging Pathogen  Fungal Morphogenesis  Fungal Pathogen  Hsp90  Transcriptional Program  
Astragalus Polysaccharide RAP Selectively Attenuates Paclitaxel-Induced Cytotoxicity Toward RAW 264.7 Cells by Reversing Cell Cycle Arrest and Apoptosis Journal article
FRONTIERS IN PHARMACOLOGY, 2019,Volume: 9
Authors:  Bao, WR;  Li, ZP;  Zhang, QW;  Li, LF;  Liu, HB;  Ma, DL;  Leung, CH;  Lu, AP;  Bian, Z;  Han, QB
Favorite | View/Download:14/0 | TC[WOS]:1 TC[Scopus]:2 | Submit date:2020/03/24
Cell Cycle  Astragalus Polysaccharide  Cytotoxicity  Protective Effect  Apoptosis  
Structure-Based Discovery of a Selective KDM5A Inhibitor that Exhibits Anti-Cancer Activity via Inducing Cell Cycle Arrest and Senescence in Breast Cancer Cell Lines Journal article
CANCERS, 2019,Volume: 11,Issue: 1
Authors:  Yang, GJ;  Ko, CN;  Zhong, HJ;  Leung, CH;  Ma, DL
Favorite | View/Download:13/0 | TC[WOS]:7 TC[Scopus]:8 | Submit date:2020/03/24
Cell Cycle Arrest  Kdm5a  Jumonji Domain  Histone Demethylation  Protein-protein Interaction  Virtual Screening  Breast Cancer  Cell Senescence  
Cyclin B1 stability is increased by interaction with BRCA1, and its overexpression suppresses the progression of BRCA1-associated mammary tumors Journal article
Experimental and Molecular Medicine, 2018,Volume: 50,Page: 136
Authors:  Choi, Eun Kyung;  Lim, Jeong-A;  Kim, Jong Kwang;  Jang, Moon Sun;  Kim, Sun Eui;  Baek, Hye Jung;  Park, Eun Jung;  Kim, Tae Hyun;  Deng, Chu-Xia;  Wang, Rui-Hong;  Kim, Sang Soo
Favorite | View/Download:40/0 | TC[WOS]:2 TC[Scopus]:4 | Submit date:2018/10/30