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Class I histone deacetylase inhibition is synthetic lethal with BRCA1 deficiency in breast cancer cells Journal article
Acta Pharmaceutica Sinica B, 2020,Volume: 10,Issue: 4,Page: 615-627
Authors:  Zhang,Baoyuan;  Lyu,Junfang;  Yang,Eun Ju;  Liu,Yifan;  Wu,Changjie;  Pardeshi,Lakhansing;  Tan,Kaeling;  Chen,Qiang;  Xu,Xiaoling;  Deng,Chu Xia;  Shim,Joong Sup
Favorite | View/Download:76/0 | TC[WOS]:0 TC[Scopus]:4 | Submit date:2020/09/16
BRCA1  Breast cancer  DNA damage  HDAC  Histone deacetylase  Reactive oxygen species  Synthetic lethality  
BRCA1 Deficiency Impairs Mitophagy and Promotes Inflammasome Activation and Mammary Tumor Metastasis Journal article
Advanced Science, 2020,Volume: 7,Issue: 6
Authors:  Chen,Qiang;  Lei,Josh Haipeng;  Bao,Jiaolin;  Wang,Haitao;  Hao,Wenhui;  Li,Licen;  Peng,Cheng;  Masuda,Takaaki;  Miao,Kai;  Xu,Jun;  Xu,Xiaoling;  Deng,Chu Xia
Favorite | View/Download:79/0 | TC[WOS]:2 TC[Scopus]:8 | Submit date:2020/09/16
ATM-AMPK-DRP1  BRCA1  inflammasomes  mitochondrial dynamics  mitophagy  
Expression of Programmed Cell Death-Ligands in Hepatocellular Carcinoma: Correlation With Immune Microenvironment and Survival Outcomes Journal article
FRONTIERS IN ONCOLOGY, 2019,Volume: 9
Authors:  Haotian Liao;  Wen Chen;  Yunlu Dai;  Joseph J. Richardson;  Junling Guo;  Kefei Yuan;  Yong Zeng;  Kunlin Xie
Favorite | View/Download:46/0 | TC[WOS]:2 TC[Scopus]:12 | Submit date:2020/05/12
Programmed Cell Death-ligands  Macrophage  Tumor Immune Stroma  Tumor Microenvironment  Antipd-1 Axis Therapy  Hepatocellular Carcinoma  
Novel Findings from Determination of Common Expressed Plasma Exosomal microRNAs in Patients with Psoriatic Arthritis, Psoriasis Vulgaris, Rheumatoid Arthritis, and Gouty Arthritisw Journal article
DISCOVERY MEDICINE, 2019,Volume: 28,Issue: 151,Page: 47-68
Authors:  Xiu-Min Chen;  Yue Zhao;  Xiao-Dong Wu;  Mao-Jie Wang;  Hua Yu;  Jin-Jian Lu;  Yuan-Jia Hu;  Qing-Chun Huang;  Run-Yue Huang;  Chuan-Jian Lu
Favorite | View/Download:27/0 | TC[WOS]:2 TC[Scopus]:0 | Submit date:2020/07/13
Non-classical estrogen signaling in ovarian cancer improves chemo-sensitivity and patients outcome Journal article
THERANOSTICS, 2019,Volume: 9,Issue: 13,Page: 3952-3965
Authors:  Dapeng Hao;  Jingjing Li;  Jianlin Wang;  Yuan Meng;  Zhiqiang Zhao;  Chao Zhang;  Kai Miao;  Chuxia Deng;  Benjamin K. Tsang;  Li Wang;  Li-jun Di
Favorite | View/Download:27/0 | TC[WOS]:2 TC[Scopus]:3 | Submit date:2020/05/21
Ovarian Cancer  Estrogen Signaling  Deficiency Of Homologous-recombination  Chemotherapy  Hormone Replacement  
Building Potent Chimeric Antigen Receptor T Cells With CRISPR Genome Editing Journal article
FRONTIERS IN IMMUNOLOGY, 2019,Volume: 10
Authors:  Jie Liu;  Guangyu Zhou;  Li Zhang;  Qi Zhao
Favorite | View/Download:9/0 | TC[WOS]:8 TC[Scopus]:24 | Submit date:2020/05/14
Chimeric Antigen Receptor  Crispr  Gene Editing  Immunotherapy  Cancer  Car t  
Rapid discrimination of colon cancer cells with single base mutation in KRAS gene segment using laser tweezers Raman spectroscopy Journal article
JOURNAL OF BIOPHOTONICS, 2019,Volume: 12,Issue: 3
Authors:  Mengmeng Liu;  Xiujie Liu;  Zufang Huang;  Xiaoqiong Tang;  Xueliang Lin;  Yunchao Xu;  Guannan Chen;  Hang Fai Kwok;  Yao Lin;  Shangyuan Feng
Favorite | View/Download:14/0 | TC[WOS]:3 TC[Scopus]:4 | Submit date:2020/05/20
Cancer Cell Screening  Kras Mutant  Optical Tweezers  Raman Spectroscopy  Single Base Mutation  
Combined use of arginase and dichloroacetate exhibits anti-proliferative effects in triple negative breast cancer cells Journal article
JOURNAL OF PHARMACY AND PHARMACOLOGY, 2019,Volume: 71,Issue: 3,Page: 306-315
Authors:  Angela Verma;  Yau-Min Lam;  Yun-Chung Leung;  Xiaohui Hu;  Xin Chen;  Edwin Cheung;  Kin Yip Tam
Favorite | View/Download:29/0 | TC[WOS]:3 TC[Scopus]:8 | Submit date:2020/05/21
Bacillus Caldovelox Arginase  Breast Cancer  Dichloroacetate  Drug Combination  Pegyated Human Arginase  
PP2AC alpha deficiency impairs early cortical development through inducing DNA damage in neuroprojenitor cells Journal article
INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY, 2019,Volume: 109,Page: 40-58
Authors:  Bo Liu;  Lin Lin;  Saima Riazuddin;  Ahmed Zubair;  Li Wang;  Li-Jun Di;  Rui Li;  Ting-Ting Dong;  Chu-Xia Deng;  Wei-Min Tong
Favorite | View/Download:18/0 | TC[WOS]:0 TC[Scopus]:0 | Submit date:2020/05/26
Protein Phosphorylation  Brain Development  Dna Damage  Stem Cell  Signaling Cascade  
CBX6 is negatively regulated by EZH2 and plays a potential tumor suppressor role in breast cancer Journal article
SCIENTIFIC REPORTS, 2019,Volume: 9
Authors:  Houliang Deng;  Xiaowen Guan;  Longcai Gong;  Jianming Zeng;  Hongjie Zhang;  Mike Y. Chen;  Gang Li
Favorite | View/Download:9/0 | TC[WOS]:1 TC[Scopus]:8 | Submit date:2020/06/22