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Class I histone deacetylase inhibition is synthetic lethal with BRCA1 deficiency in breast cancer cells Journal article
Acta Pharmaceutica Sinica B, 2020,Volume: 10,Issue: 4,Page: 615-627
Authors:  Zhang,Baoyuan;  Lyu,Junfang;  Yang,Eun Ju;  Liu,Yifan;  Wu,Changjie;  Pardeshi,Lakhansing;  Tan,Kaeling;  Chen,Qiang;  Xu,Xiaoling;  Deng,Chu Xia;  Shim,Joong Sup
Favorite | View/Download:73/0 | TC[WOS]:0 TC[Scopus]:1 | Submit date:2020/09/16
BRCA1  Breast cancer  DNA damage  HDAC  Histone deacetylase  Reactive oxygen species  Synthetic lethality  
Targeted Delivery of a Ligand−Drug Conjugate via Formyl Peptide Receptor 1 through Cholesterol-Dependent Endocytosis Journal article
MOLECULAR PHARMACEUTICS, 2019,Volume: 16,Issue: 6,Page: 2636-2647
Authors:  Junlin Wang;  Meiwan Chen;  Shaoping Li;  Richard D. Ye
Favorite | View/Download:20/0 | TC[WOS]:1 TC[Scopus]:0 | Submit date:2020/01/07
g Protein-coupled Receptors  Ph-sensitive Peptides Conjugates  Formyl Peptides  Receptor Internalization  Targeted Drug Delivery  
CuS Nanoparticles as a Photodynamic Nanoswitch for Abrogating Bypass Signaling To Overcome Gefitinib Resistance Journal article
NANO LETTERS, 2019,Volume: 19,Issue: 5,Page: 3344-3352
Authors:  Xiajing Gu;  Yuanyuan Qiu;  Miao Lin;  Kai Cui;  Gaoxian Chen;  Yingzhi Chen;  Chenchen Fan;  Yongming Zhang;  Lu Xu;  Hongzhuan Chen;  Jian-Bo Wan;  Wei Lu;  Zeyu Xiao
Favorite | View/Download:11/0 | TC[WOS]:3 TC[Scopus]:0 | Submit date:2020/04/22
Gefitinib  Cus Nanoparticles  Non-small Cell Lung Cancer  Rug Resistance  Active Oxygen Species  
Aurone derivatives as Vps34 inhibitors that modulate autophagy Journal article
ACTA PHARMACEUTICA SINICA B, 2019,Volume: 9,Issue: 3,Page: 537-544
Authors:  Guodong Li;  Joshua William Boyle;  Chung-Nga Ko;  Wu Zeng;  Vincent Kam Wai Wong;  Jian-Bo Wan;  Philip Wai Hong Chan;  Dik-Lung Ma;  Chung-Hang Leung
Favorite | View/Download:13/0 | TC[WOS]:2 TC[Scopus]:0 | Submit date:2020/03/24
Autophagy  Natural Products  Vps34  Inhibitor  Structure-based Virtualscreening  Vesicle Trafficking  Heart Or Liver Damage  Aurone Derivative  
A multidirectional investigation of stem bark extracts of four African plants: HPLC-MS/MS profiling and biological potentials Journal article
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2019,Volume: 168,Page: 217-224
Authors:  Kouadio Bene;  Kouadio Ibrahime Sinan;  Gokhan Zengin;  Alina Diuzheva;  József Jekő;  Zoltán Cziáky;  Muhammad Zakariyyah Aumeeruddy;  Jianbo Xiao;  Mohamad Fawzi Mahomoodally
Favorite | View/Download:9/0 | TC[WOS]:1 TC[Scopus]:0 | Submit date:2020/04/24
Senna Siamea  Distemonanthus Benthamianus  Harrisonia Abyssinica  Pycnanthus Angolensis  Enzyme Inhibitors  Bio-pharmaceutical  
Structure-Based in Silico Screening Identifies a Potent Ebolavirus Inhibitor from a Traditional Chinese Medicine Library Journal article
Journal of Medicinal Chemistry, 2019,Volume: 62,Issue: 6,Page: 2928-2937
Authors:  Shaikh F.;  Zhao Y.;  Alvarez L.;  Iliopoulou M.;  Lohans C.;  Schofield C.J.;  Padilla-Parra S.;  Siu S.W.I.;  Fry E.E.;  Ren J.;  Stuart D.I.
Favorite | View/Download:15/0 | TC[WOS]:3 TC[Scopus]:0 | Submit date:2019/04/04
Synthesis and Evaluation of Dibenzothiophene Analogues as Pin1 Inhibitors for Cervical Cancer Therapy Journal article
ACS OMEGA, 2019,Volume: 4,Issue: 5,Page: 9228-9234
Authors:  Wu, KJ;  Liu, X;  Wong, SY;  Zhou, YY;  Ma, DL;  Leung, CH
Favorite | View/Download:13/0 | TC[WOS]:1 TC[Scopus]:0 | Submit date:2020/03/24
Small molecules for fat combustion: targeting obesity Journal article
ACTA PHARMACEUTICA SINICA B, 2019,Volume: 9,Issue: 2,Page: 220-236
Authors:  Liu, JX;  Wang, YT;  Lin, LG
Favorite | View/Download:9/0 | TC[WOS]:5 TC[Scopus]:0 | Submit date:2020/03/20
Obesity  Thermogenesis  Brown Adipose Tissue  Beige Cells  Uncoupling Protein 1  
Structure-Based Discovery of a Selective KDM5A Inhibitor that Exhibits Anti-Cancer Activity via Inducing Cell Cycle Arrest and Senescence in Breast Cancer Cell Lines Journal article
CANCERS, 2019,Volume: 11,Issue: 1
Authors:  Yang, GJ;  Ko, CN;  Zhong, HJ;  Leung, CH;  Ma, DL
Favorite | View/Download:12/0 | TC[WOS]:7 TC[Scopus]:0 | Submit date:2020/03/24
Cell Cycle Arrest  Kdm5a  Jumonji Domain  Histone Demethylation  Protein-protein Interaction  Virtual Screening  Breast Cancer  Cell Senescence  
Investigation of the impact of ferrous species on the performance of common oilfield scale inhibitors for mineral scale control Journal article
JOURNAL OF PETROLEUM SCIENCE AND ENGINEERING, 2019,Volume: 172,Page: 288-296
Authors:  Zhang, Ping;  Zhang, Zhang;  Liu, Yuan;  Kan, Amy T.;  Tomson, Mason B.
Favorite | View/Download:15/0 | TC[WOS]:3 TC[Scopus]:0 | Submit date:2019/01/17
Scale inhibitor  Barium sulfate  Ferrous  Anoxic  Inhibition efficiency